| (1) BlackRock, Inc. |
Delaware |
1115027 |
0 |
1115027 |
0 |
1115027 |
2.8 % |
07/10/2022 |
| Molly G. Hardie |
United States of America |
0 |
3451152 |
0 |
3451152 |
3451152 |
8.5 % |
16/02/2022 |
| Robert D. Hardie |
United States of America |
0 |
3451152 |
0 |
3451152 |
3451152 |
8.5 % |
16/02/2022 |
| The Paul B. Manning Revocable Trust dated May 10, 2000 |
Virginia |
3040193 |
0 |
3040193 |
0 |
3040193 |
7.5 % |
14/02/2022 |
| Paul B. Manning |
Delaware |
3352693 |
657985 |
3352693 |
657985 |
4010678 |
9.9 % |
14/02/2022 |
| BKB Growth Investments, LLC |
Delaware |
657985 |
0 |
657985 |
0 |
657985 |
1.6 % |
14/02/2022 |
| James B. Murray, Jr. |
|
2581057 |
0 |
2581057 |
0 |
2581057 |
6.4 % |
14/02/2022 |
| (1) BlackRock, Inc. |
Delaware |
3103996 |
0 |
3109670 |
0 |
3109670 |
7.7 % |
04/02/2022 |
| Deep Track Capital, LP |
Delaware |
0 |
2414917 |
0 |
0 |
2414917 |
5.97 % |
27/01/2022 |
| Deep Track Biotechnology Master Fund, Ltd. |
Delaware |
0 |
2414917 |
0 |
0 |
2414917 |
5.97 % |
27/01/2022 |
| David Kroin |
Delaware |
0 |
2414917 |
0 |
0 |
2414917 |
5.97 % |
27/01/2022 |
| RA Capital Management, L.P. |
Delaware |
0 |
9770773 |
0 |
10 |
9770773 |
25.3 % |
16/07/2021 |
| Peter Kolchinsky |
United States |
0 |
9770773 |
0 |
10 |
9770773 |
25.3 % |
16/07/2021 |
| Rajeev Shah |
United States |
0 |
9770773 |
0 |
10 |
9770773 |
25.3 % |
16/07/2021 |
| RA Capital Healthcare Fund, L.P. |
Delaware |
0 |
7881889 |
0 |
10 |
7881889 |
20.4 % |
16/07/2021 |
| Frank M. Sands |
State of Delaware |
0 |
3417075 |
0 |
3417075 |
3417075 |
8.84 % |
12/07/2021 |
| Sands Capital Global Venture Fund II, L.P. |
State of Delaware |
0 |
1146173 |
0 |
1146173 |
1146173 |
2.97 % |
12/07/2021 |
| Sands Capital Life Sciences Pulse Fund, LLC |
State of Delaware |
0 |
1146173 |
0 |
1146173 |
1146173 |
2.97 % |
12/07/2021 |
| Sands Capital Ventures Discovery Fund III, L.P. |
State of Delaware |
0 |
1124729 |
0 |
1124729 |
1124729 |
2.91 % |
12/07/2021 |
