| Biotechnology Value Trading Fund OS LP |
|
0 |
0 |
0 |
420150 |
420150 |
1 % |
14/02/2022 |
| BVF Partners L.P. |
|
0 |
0 |
0 |
7062379 |
7062379 |
9.7 % |
14/02/2022 |
| Mark N. Lampert |
|
0 |
0 |
0 |
7062379 |
7062379 |
9.7 % |
14/02/2022 |
| BVF II GP LLC |
|
0 |
0 |
0 |
2862430 |
2862430 |
3.9 % |
14/02/2022 |
| BVF Inc. |
|
0 |
0 |
0 |
7062379 |
7062379 |
9.7 % |
14/02/2022 |
| BVF Partners OS Ltd. |
|
0 |
0 |
0 |
420150 |
420150 |
1 % |
14/02/2022 |
| Biotechnology Value Fund, L.P. |
|
0 |
0 |
0 |
3648633 |
3648633 |
5 % |
14/02/2022 |
| BVF GP Holdings LLC |
|
0 |
0 |
0 |
6511063 |
6511063 |
9 % |
14/02/2022 |
| BVF I GP LLC |
|
0 |
0 |
0 |
3648633 |
3648633 |
5 % |
14/02/2022 |
| Biotechnology Value Trading Fund II, L.P. |
|
0 |
0 |
0 |
2862430 |
2862430 |
3.9 % |
14/02/2022 |
| EcoR1 Capital Fund Qualified, L.P. |
Delaware |
0 |
664298 |
0 |
664298 |
664298 |
11 % |
14/02/2022 |
| Oleg Nodelman |
United States |
0 |
749585 |
0 |
749585 |
749585 |
11 % |
14/02/2022 |
| EcoR1 Capital, LLC |
Delaware |
0 |
749585 |
0 |
749585 |
749585 |
11 % |
14/02/2022 |
| MIG Verwaltungs AG |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| FCPB Affi GmbH |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| HMW Emissionshaus AG |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| First Capital Partner GmbH |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 4 KG |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| Athos KG |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| Affiris AG |
Germany |
0 |
0 |
0 |
0 |
7106840 |
8.46 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 15 geschlossene Investment-KG |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG Asset Trust GmbH |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 5 KG i.L. |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 7 KG i.L. |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 11 KG i.L. |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 12 geschlossene Investment-KG |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG GmbH & Co. Fonds 13 geschlossene Investment-KG |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| HMW Verwaltungs GmbH |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| Michael Motschmann |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| MIG Komplementär GmbH |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| HMW Komplementär GmbH |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| Dr. Matthias Hallweger |
Germany |
0 |
0 |
0 |
7106840 |
7106840 |
8.46 % |
05/08/2021 |
| Santo Venture Capital GmbH |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| Santo Holding (Deutschland) GmbH |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| FCP Biotech Holding GmbH |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| we holding GmbH & Co. KG |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| Wolfgang Egger |
Germany |
0 |
0 |
0 |
7106840 |
8620157 |
10.1 % |
05/08/2021 |
| Eli Lilly and Company |
|
3615328 |
0 |
3615328 |
0 |
3615328 |
5 % |
12/02/2021 |
| DH-Capital GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| OH Beteiligungen GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| dievini Hopp BioTech holding GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| Dietmar Hopp |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| Oliver Hopp |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| Daniel Hopp |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| Prof. Dr. Friedrich von Bohlen und Halbach |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| Prof. Dr. Christof Hettich |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| Dr. Mathias Hothum |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
25.1 % |
12/02/2021 |
| EcoR1 Capital Fund Qualified, L.P. |
Delaware |
0 |
3964473 |
0 |
3964473 |
3964473 |
11 % |
22/01/2021 |
| EcoR1 Capital, LLC |
Delaware |
0 |
4702160 |
0 |
4702160 |
4702160 |
11 % |
22/01/2021 |
| Oleg Nodelman |
Delaware |
0 |
4702160 |
0 |
4702160 |
4702160 |
11 % |
22/01/2021 |
| BVF GP HOLDINGS LLC |
Delaware |
0 |
0 |
0 |
7256763 |
7256763 |
10.1 % |
14/01/2021 |
| Biotechnology Value Fund, L.P. |
Delaware |
0 |
0 |
0 |
4178515 |
4178515 |
5.8 % |
14/01/2021 |
| BVF I GP LLC |
Delaware |
0 |
0 |
0 |
4178515 |
4178515 |
5.8 % |
14/01/2021 |
| Biotechnology Value Trading Fund OS LP |
Delaware |
0 |
0 |
0 |
505763 |
505763 |
1 % |
14/01/2021 |
| Mark N. Lampert |
Delaware |
0 |
0 |
0 |
7916658 |
7916658 |
11 % |
14/01/2021 |
| BVF Inc. |
Delaware |
0 |
0 |
0 |
7916658 |
7916658 |
11 % |
14/01/2021 |
| BVF Partners OS Ltd. |
Delaware |
0 |
0 |
0 |
505763 |
505763 |
1 % |
14/01/2021 |
| BVF Partners L.P. |
Delaware |
0 |
0 |
0 |
7916658 |
7916658 |
11 % |
14/01/2021 |
| BVF II GP LLC |
Delaware |
0 |
0 |
0 |
3078248 |
3078248 |
4.3 % |
14/01/2021 |
| Biotechnology Value Trading Fund II, L.P. |
Delaware |
0 |
0 |
0 |
3078248 |
3078248 |
4.3 % |
14/01/2021 |
| BVF Partners OS Ltd. |
|
0 |
0 |
0 |
815726 |
815726 |
1.2 % |
14/02/2020 |
| Biotechnology Value Fund, L.P. |
|
0 |
0 |
0 |
5605420 |
5605420 |
8.3 % |
14/02/2020 |
| BVF I GP LLC |
|
0 |
0 |
0 |
5605420 |
5605420 |
8.3 % |
14/02/2020 |
| Biotechnology Value Trading Fund II, L.P. |
|
0 |
0 |
0 |
4547527 |
4547527 |
6.7 % |
14/02/2020 |
| BVF II GP LLC |
|
0 |
0 |
0 |
4547527 |
4547527 |
6.7 % |
14/02/2020 |
| Biotechnology Value Trading Fund OS LP |
|
0 |
0 |
0 |
815726 |
815726 |
1.2 % |
14/02/2020 |
| BVF GP HOLDINGS LLC |
|
0 |
0 |
0 |
10152947 |
10152947 |
15 % |
14/02/2020 |
| BVF Partners L.P. |
|
0 |
0 |
0 |
11342505 |
11342505 |
16.8 % |
14/02/2020 |
| BVF Inc. |
|
0 |
0 |
0 |
11342505 |
11342505 |
16.8 % |
14/02/2020 |
| Mark N. Lampert |
|
0 |
0 |
0 |
11342505 |
11342505 |
16.8 % |
14/02/2020 |
| dievini Hopp BioTech holding GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
26.7 % |
06/02/2020 |
| DH-Capital GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
26.7 % |
06/02/2020 |
| OH Beteiligungen GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
26.7 % |
06/02/2020 |
| Dietmar Hopp |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
26.7 % |
06/02/2020 |
| Oliver Hopp |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
26.7 % |
06/02/2020 |
| Daniel Hopp |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
26.7 % |
06/02/2020 |
| Prof. Dr. Christof Hettich |
Germany |
174750 |
18041000 |
174750 |
18041000 |
18215750 |
27 % |
06/02/2020 |
| Prof. Dr. Friedrich von Bohlen und Halbach |
Germany |
11828 |
18041000 |
11828 |
18041000 |
18052828 |
26.7 % |
06/02/2020 |
| Biotechnology Value Fund, L.P. |
Delaware |
0 |
0 |
0 |
5580788 |
5580788 |
8.3 % |
16/09/2019 |
| BVF Inc. |
Delaware |
0 |
0 |
0 |
11297911 |
11297911 |
16.7 % |
16/09/2019 |
| BVF Partners L.P. |
Delaware |
0 |
0 |
0 |
11297911 |
11297911 |
16.7 % |
16/09/2019 |
| Biotechnology Value Trading Fund OS LP |
Delaware |
0 |
0 |
0 |
812271 |
812271 |
1.2 % |
16/09/2019 |
| BVF Partners OS Ltd. |
Delaware |
0 |
0 |
0 |
812271 |
812271 |
1.2 % |
16/09/2019 |
| Biotechnology Value Fund II, L.P. |
Delaware |
0 |
0 |
0 |
4537717 |
4537717 |
6.7 % |
16/09/2019 |
| Mark N. Lampert |
Delaware |
0 |
0 |
0 |
11297911 |
11297911 |
16.7 % |
16/09/2019 |
| Biotechnology Value Fund, L.P. |
Delaware |
0 |
0 |
0 |
3574717 |
3574717 |
5.3 % |
21/03/2019 |
| BVF Partners OS Ltd. |
Delaware |
0 |
0 |
0 |
516862 |
516862 |
1 % |
21/03/2019 |
| Biotechnology Value Fund II, L.P. |
Delaware |
0 |
0 |
0 |
2960945 |
2960945 |
4.4 % |
21/03/2019 |
| Biotechnology Value Trading Fund OS LP |
Delaware |
0 |
0 |
0 |
516862 |
516862 |
1 % |
21/03/2019 |
| Mark N. Lampert |
Delaware |
0 |
0 |
0 |
7455534 |
7455534 |
11 % |
21/03/2019 |
| BVF Partners L.P. |
Delaware |
0 |
0 |
0 |
7455534 |
7455534 |
11 % |
21/03/2019 |
| BVF Inc. |
Delaware |
0 |
0 |
0 |
7455534 |
7455534 |
11 % |
21/03/2019 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
5612758 |
0 |
5612758 |
8.321 % |
13/02/2019 |
| FMR LLC |
Delaware |
215120 |
0 |
5612758 |
0 |
5612758 |
8.321 % |
13/02/2019 |
| Dr. Friedrich von Bohlen und Halbach |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| Beteiligungen GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| Hopp |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| Hopp |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| Dr. Christof Hettich |
Germany |
174750 |
18041000 |
174750 |
0 |
18215750 |
27 % |
04/02/2019 |
| Hopp BioTech holding GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| Hopp |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| GmbH & Co. KG |
Germany |
0 |
18041000 |
0 |
0 |
18041000 |
26.8 % |
04/02/2019 |
| of 14 Pages |
Germany |
51250 |
18041000 |
51250 |
18041000 |
18092250 |
32.1 % |
14/02/2017 |
| of 14 Pages |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
32 % |
14/02/2017 |
| of 14 Pages |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
32 % |
14/02/2017 |
| of 14 Pages |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
32 % |
14/02/2017 |
| of 14 Pages |
Germany |
78750 |
18041000 |
78750 |
18041000 |
18119750 |
32.2 % |
14/02/2017 |
| of 14 Pages |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
32 % |
14/02/2017 |
| of 14 Pages |
Germany |
174750 |
18041000 |
174750 |
18041000 |
18215750 |
32.4 % |
14/02/2017 |
| of 14 Pages |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
32 % |
14/02/2017 |
| of 14 Pages |
Germany |
0 |
18041000 |
0 |
18041000 |
18041000 |
32 % |
14/02/2017 |
| Andrea Pfeifer |
German |
3076500 |
0 |
3076500 |
0 |
3076500 |
5.46 % |
13/02/2017 |
| Varuma AG |
Basel, Switzerland |
11400000 |
0 |
11400000 |
0 |
11400000 |
20.25 % |
13/02/2017 |