| Paradigm BioCapital International Fund Ltd. |
Cayman Islands |
4119565 |
0 |
4119565 |
0 |
4119565 |
7.7 % |
14/11/2024 |
| Paradigm BioCapital Advisors LP |
Delaware |
4800000 |
0 |
4800000 |
0 |
4800000 |
8.9 % |
14/11/2024 |
| Paradigm BioCapital Advisors GP LLC |
Delaware |
4800000 |
0 |
4800000 |
0 |
4800000 |
8.9 % |
14/11/2024 |
| Senai Asefaw, M.D. |
United States of America |
4800000 |
0 |
4800000 |
0 |
4800000 |
8.9 % |
14/11/2024 |
| FMR LLC |
Delaware |
6477931 |
0 |
6479273 |
0 |
6479273 |
12.053 % |
12/11/2024 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
6479273 |
0 |
6479273 |
12.053 % |
12/11/2024 |
| BlackRock, Inc. |
Delaware |
4142828 |
0 |
4246692 |
0 |
4246692 |
7.9 % |
08/11/2024 |
| BlackRock, Inc. |
Delaware |
0 |
0 |
4246692 |
0 |
4246692 |
7.9 % |
22/10/2024 |
| Gilead Sciences, Inc. |
Delaware |
6720803 |
0 |
6720803 |
0 |
6720803 |
12.9 % |
28/12/2023 |
| Dr. Senai Asefaw |
United States America |
2422700 |
0 |
2422700 |
0 |
2422700 |
5.05 % |
21/07/2023 |
| Paradigm BioCapital Advisors LP |
Delaware |
2422700 |
0 |
2422700 |
0 |
2422700 |
5.05 % |
21/07/2023 |
| Paradigm BioCapital International Fund Ltd. |
Cayman Islands |
1954301 |
0 |
1954301 |
0 |
1954301 |
4.07 % |
21/07/2023 |
| Dr. Senai Asefaw |
United States America |
2422700 |
0 |
2422700 |
0 |
2422700 |
5.05 % |
21/07/2023 |
| Paradigm BioCapital Advisors GP LLC |
Delaware |
2422700 |
0 |
2422700 |
0 |
2422700 |
5.05 % |
21/07/2023 |
| Paradigm BioCapital International Fund Ltd. |
Cayman Islands |
1954301 |
0 |
1954301 |
0 |
1954301 |
4.07 % |
21/07/2023 |
| Paradigm BioCapital Advisors LP |
Delaware |
2422700 |
0 |
2422700 |
0 |
2422700 |
5.05 % |
21/07/2023 |
| Paradigm BioCapital Advisors GP LLC |
Delaware |
2422700 |
0 |
2422700 |
0 |
2422700 |
5.05 % |
21/07/2023 |
| BlackRock, Inc. |
Delaware |
2106823 |
0 |
2156149 |
0 |
2156149 |
4.9 % |
09/02/2023 |
| BlackRock, Inc. |
Delaware |
2155720 |
0 |
2207179 |
0 |
2207179 |
5 % |
08/02/2023 |
| Gilead Sciences, Inc. |
Delaware |
3478261 |
0 |
3478261 |
0 |
3478261 |
7.3 % |
06/02/2023 |
| Novo Holdings A/S |
Denmark |
1750000 |
0 |
1750000 |
0 |
1750000 |
4 % |
12/12/2022 |
| Novo Holdings A/S |
Denmark |
2507076 |
0 |
2507076 |
0 |
2507076 |
5.7 % |
28/11/2022 |
| Cormorant Global Healthcare GP, LLC |
Delaware |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Bihua Chen |
United States |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Cormorant Asset Management, LP |
Delaware |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Cormorant Global Healthcare GP, LLC |
Delaware |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Bihua Chen |
United States |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Cormorant Asset Management, LP |
Delaware |
|
|
|
|
2200000 |
5.02 % |
29/08/2022 |
| Averill Master Fund, Ltd. |
Cayman Islands |
0 |
2470559 |
0 |
2470559 |
2470559 |
5.8 % |
27/06/2022 |
| Aaron Cowen |
U.S.A. |
0 |
2470559 |
0 |
2470559 |
2470559 |
5.8 % |
27/06/2022 |
| Suvretta Capital Management, LLC |
Delaware |
0 |
2470559 |
0 |
2470559 |
2470559 |
5.8 % |
27/06/2022 |
| Averill Master Fund, Ltd. |
Cayman Islands |
0 |
2470559 |
0 |
2470559 |
2470559 |
5.8 % |
27/06/2022 |
| Aaron Cowen |
U.S.A. |
0 |
2470559 |
0 |
2470559 |
2470559 |
5.8 % |
27/06/2022 |
| Suvretta Capital Management, LLC |
Delaware |
0 |
2470559 |
0 |
2470559 |
2470559 |
5.8 % |
27/06/2022 |
| Novo Holdings A/S |
Denmark |
4016878 |
0 |
4016878 |
0 |
4016878 |
11.4 % |
09/02/2022 |