| (1) BlackRock, Inc. |
Delaware |
6868108 |
0 |
0 |
0 |
6942699 |
6 % |
08/11/2024 |
| Morgan Stanley Capital Services LLC |
Delaware. |
0 |
8021388 |
0 |
8021388 |
8021388 |
7 % |
06/11/2024 |
| Morgan Stanley |
Delaware. |
0 |
9899613 |
0 |
9901213 |
9901213 |
8.6 % |
06/11/2024 |
| (1) BlackRock, Inc. |
Delaware |
0 |
0 |
6942699 |
0 |
6942699 |
6 % |
24/10/2024 |
| EIN #00-0000000 |
Jersey, Channel Islands |
0 |
6414642 |
0 |
6414642 |
6414642 |
6.1 % |
08/03/2024 |
| 00-0000000 |
Cayman Islands |
0 |
6128928 |
0 |
6128928 |
6128928 |
5.8 % |
08/03/2024 |
| Vestal Point Capital, LP |
Delaware |
0 |
4155000 |
0 |
0 |
4155000 |
5.4 % |
13/02/2024 |
| Ryan Wilder |
United States |
0 |
4155000 |
0 |
0 |
4155000 |
5.4 % |
13/02/2024 |
| Perceptive Life Sciences Master Fund, Ltd. |
Delaware |
0 |
4580249 |
0 |
4580249 |
4580249 |
5.9 % |
06/12/2023 |
| Joseph Edelman |
Delaware |
0 |
4580249 |
0 |
4580249 |
4580249 |
5.9 % |
06/12/2023 |
| Perceptive Advisors LLC |
Delaware |
0 |
4580249 |
0 |
4580249 |
4580249 |
5.9 % |
06/12/2023 |
| Shah, Nimish |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| Koh, Bong |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| Venrock Healthcare Capital Partners III, L.P. |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| VHCP Co-Investment Holdings III, LLC |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| Venrock Healthcare Capital Partners EG, L.P. |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| VHCP Management III, LLC |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| VHCP Management EG, LLC |
Delaware |
0 |
5797585 |
0 |
5797585 |
5797585 |
9.99 % |
08/05/2023 |
| Kawas |
Delaware |
0 |
2374761 |
0 |
0 |
4757382 |
9.9 % |
02/05/2023 |
| Bio Management, LLC |
Delaware |
0 |
2374761 |
0 |
0 |
4757382 |
9.9 % |
02/05/2023 |
| Propel Bio Partners LP |
Delaware |
2505381 |
0 |
2505381 |
0 |
2505381 |
5.21 % |
14/02/2023 |
| Alyeska Fund GP, LLC |
Delaware |
0 |
4805000 |
0 |
0 |
4805000 |
9.99 % |
14/02/2023 |
| Anand Parekh |
United States of America |
0 |
4805000 |
0 |
0 |
4805000 |
9.99 % |
14/02/2023 |
| Alyeska Investment Group, L.P. |
Delaware |
0 |
4805000 |
0 |
0 |
4805000 |
9.99 % |
14/02/2023 |
| Steven Boyd |
United States of America |
0 |
5333951 |
0 |
0 |
5333951 |
9.99 % |
14/02/2023 |
| Armistice Capital, LLC |
Delaware |
0 |
5333951 |
0 |
0 |
5333951 |
9.99 % |
14/02/2023 |
| FMR LLC |
Delaware |
2972371 |
0 |
2972371 |
0 |
2972371 |
6.184 % |
09/02/2023 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
2972371 |
0 |
2972371 |
6.184 % |
09/02/2023 |
| Franklin Resources, Inc. |
USA |
4 |
4 |
4 |
4 |
4775484 |
9.9 % |
30/01/2023 |
| Fred Knoll |
Florida |
0 |
3450000 |
0 |
3450000 |
3450000 |
7.18 % |
23/01/2023 |
| Shoshana Shendelman |
|
5078741 |
2492094 |
5078741 |
11 |
7570835 |
14.9 % |
14/10/2022 |
| Franklin Resources, Inc. |
USA |
4 |
4 |
4 |
4 |
4775484 |
10.3 % |
08/07/2022 |
| Alexandria Equities No. 7, LLC |
Delaware |
0 |
5043977 |
0 |
5043977 |
5043977 |
10.3 % |
29/06/2022 |
| Alexandria Venture Investments, LLC |
Delaware |
0 |
7925077 |
0 |
8390077 |
8390077 |
16.8 % |
29/06/2022 |
| Alexandria Real Estate Equities, Inc. |
Maryland |
0 |
12969054 |
0 |
13434054 |
13434054 |
19.9 % |
29/06/2022 |
| Alexandria Real Estate Equities, Inc. |
Maryland |
0 |
2969054 |
0 |
0 |
3434054 |
13.1 % |
11/02/2022 |
| Alexandria Equities No. 7, LLC |
Delaware |
0 |
1243977 |
0 |
0 |
1243977 |
4.7 % |
11/02/2022 |
| Alexandria Venture Investments, LLC |
Delaware |
0 |
1725077 |
0 |
0 |
2190077 |
8.4 % |
11/02/2022 |
| OrbiMed Capital LLC |
Delaware |
2100681 |
0 |
2100681 |
0 |
2100681 |
8 % |
11/02/2022 |
| OrbiMed Advisors LLC |
Delaware |
0 |
213000 |
0 |
0 |
213000 |
0.8 % |
11/02/2022 |
| Shoshana Shendelman |
|
4690462 |
2492094 |
4690462 |
11 |
7182556 |
25 % |
28/01/2022 |
| Point72 Asset Management, L.P. |
Citizenship or place of organization Delaware |
0 |
2549000 |
0 |
2549000 |
2549000 |
4 % |
04/01/2022 |
| Point72 Hong Kong Limited |
Citizenship or place of organization Hong Kong |
0 |
550 |
0 |
550 |
550 |
4 % |
04/01/2022 |
| Point72 Capital Advisors, Inc. |
Citizenship or place of organization Delaware |
0 |
2549000 |
0 |
2549000 |
2549000 |
4 % |
04/01/2022 |
| Cubist Systematic Strategies, LLC |
Citizenship or place of organization Delaware |
0 |
7426 |
0 |
7426 |
7426 |
4 % |
04/01/2022 |
| Steven A. Cohen |
Citizenship or place of organization United States |
0 |
2556976 |
0 |
2556976 |
2556976 |
4 % |
04/01/2022 |
| Shoshana Shendelman |
|
4162172 |
2492094 |
4162172 |
11 |
6654266 |
23.8 % |
16/04/2021 |
| Alexandria Venture Investments, LLC |
Delaware |
0 |
0 |
0 |
0 |
2146599 |
9.5 % |
12/02/2021 |
| Alexandria Equities No. 7, LLC |
Delaware |
0 |
1243977 |
0 |
0 |
1243977 |
5.5 % |
12/02/2021 |
| Alexandria Real Estate Equities, Inc. |
Maryland |
0 |
2925576 |
0 |
0 |
3390576 |
15.1 % |
12/02/2021 |
| OrbiMed Advisors LLC |
Delaware |
0 |
105006 |
0 |
0 |
105006 |
0.47 % |
12/02/2021 |
| OrbiMed Capital LLC |
Delaware |
1666825 |
0 |
1666825 |
0 |
1666825 |
7.41 % |
12/02/2021 |
| Shoshana Shendelman |
|
3843963 |
2492094 |
3843963 |
11 |
6336057 |
26.5 % |
14/08/2020 |
| FMR LLC |
Delaware |
11718 |
0 |
2227957 |
0 |
2227957 |
10.069 % |
10/08/2020 |
| Abigail P. Johnson |
Delaware |
0 |
0 |
2227957 |
0 |
2227957 |
10.069 % |
10/08/2020 |
| Shoshana Shendelman |
|
3901990 |
2492094 |
3901990 |
2492094 |
6394084 |
27 % |
01/06/2020 |
| OrbiMed Capital LLC |
Delaware |
0 |
849254 |
0 |
0 |
849254 |
4.59 % |
14/02/2020 |
| Advisors LLC |
Delaware |
0 |
137932 |
0 |
0 |
137932 |
0.74 % |
14/02/2020 |
| Alexandria Venture Investments, LLC |
Delaware |
0 |
706599 |
0 |
1171599 |
1171599 |
6.3 % |
14/02/2020 |
| Alexandria Equities No. 7, LLC |
Delaware |
0 |
2218977 |
0 |
2218977 |
2218977 |
12 % |
14/02/2020 |
| Inc. |
Maryland |
0 |
2925576 |
0 |
3390576 |
3390576 |
18.3 % |
14/02/2020 |
| Alexandria Venture Investments, LLC |
Delaware |
0 |
1171599 |
0 |
0 |
1171599 |
6.9 % |
28/05/2019 |
| Alexandria Real Estate Equities, Inc. |
Maryland |
0 |
3390576 |
0 |
0 |
3390576 |
19.9 % |
28/05/2019 |
| Alexandria Equities No. 7, LLC |
Delaware |
0 |
2218977 |
0 |
0 |
2218977 |
13 % |
28/05/2019 |