| STATE STREET CORPORATION |
BOSTON, MASSACHUSETTS |
0 |
4414673 |
0 |
4485615 |
4485615 |
12.5 % |
10/04/2024 |
| SSGA FUNDS MANAGEMENT, INC. |
BOSTON, MASSACHUSETTS |
0 |
4032510 |
0 |
4036410 |
4036410 |
11.25 % |
10/04/2024 |
| Benjamin Alexander Smith |
Delaware |
0 |
2736367 |
0 |
0 |
2736367 |
7.66 % |
08/02/2024 |
| Janaka Sheehan Maduraperuma |
Delaware |
0 |
2736367 |
0 |
0 |
2736367 |
7.66 % |
08/02/2024 |
| Laurion Capital Management LP |
Delaware |
0 |
2736367 |
0 |
0 |
2736367 |
7.66 % |
08/02/2024 |
| (1) BlackRock, Inc. |
Delaware |
2132212 |
0 |
2156342 |
0 |
2156342 |
6 % |
29/01/2024 |
| Julian C. Baker |
United States |
2104559 |
0 |
2104559 |
0 |
2104559 |
7.2 % |
14/02/2023 |
| Baker Bros. Advisors LP |
Delaware |
2104559 |
0 |
2104559 |
0 |
2104559 |
7.2 % |
14/02/2023 |
| Felix J. Baker |
United States |
2104559 |
0 |
2104559 |
0 |
2104559 |
7.2 % |
14/02/2023 |
| Baker Bros. Advisors (GP) LLC |
Delaware |
2104559 |
0 |
2104559 |
0 |
2104559 |
7.2 % |
14/02/2023 |
| (1) BlackRock, Inc. |
Delaware |
866997 |
0 |
866997 |
0 |
866997 |
3 % |
08/07/2022 |
| Aaron I. Davis |
|
0 |
73186 |
0 |
73186 |
73186 |
0.3 % |
14/02/2022 |
| Joe Lewis |
|
0 |
1188405 |
0 |
1188405 |
1188405 |
4.1 % |
14/02/2022 |
| Boxer Asset Management Inc. |
|
0 |
1188405 |
0 |
1188405 |
1188405 |
4.1 % |
14/02/2022 |
| Boxer Capital, LLC |
|
0 |
1188405 |
0 |
1188405 |
1188405 |
4.1 % |
14/02/2022 |
| MVA Investors, LLC |
|
0 |
73186 |
0 |
73186 |
73186 |
0.3 % |
14/02/2022 |
| Thomas Butler |
|
527992 |
4846132 |
527992 |
4846132 |
5374124 |
18.3 % |
11/02/2022 |
| Point Sur Investors, LLC |
|
4365342 |
0 |
4365342 |
0 |
4365342 |
15 % |
11/02/2022 |
| Point Sur Investors Fund I, L.P. |
|
480790 |
0 |
480790 |
0 |
480790 |
1.7 % |
11/02/2022 |
| Point Sur Investors, LLC |
|
4365342 |
0 |
4365342 |
0 |
4365342 |
15 % |
11/02/2022 |
| Point Sur Investors Fund I, L.P. |
|
480790 |
0 |
480790 |
0 |
480790 |
1.7 % |
11/02/2022 |
| Rainer M. Erdtmann |
|
141567 |
4846132 |
141567 |
4846132 |
4987699 |
17.1 % |
11/02/2022 |
| EIN #00-0000000 |
Jersey, Channel Islands |
0 |
3527286 |
0 |
3527286 |
3527286 |
12.1 % |
10/02/2022 |
| (1)Names of reporting persons. BlackRock, Inc. |
Delaware |
1670951 |
0 |
1672808 |
0 |
1672808 |
5.8 % |
04/02/2022 |
| EIN #00-0000000 |
Jersey, Channel Islands |
0 |
3159146 |
0 |
3159146 |
3159146 |
11 % |
10/08/2021 |
| Boxer Capital, LLC |
Delaware |
0 |
2088405 |
0 |
0 |
2088405 |
7.3 % |
30/04/2021 |
| MVA Investors, LLC |
Delaware |
0 |
73186 |
0 |
0 |
73186 |
0.3 % |
30/04/2021 |
| Boxer Asset Management Inc. |
Delaware |
0 |
2088405 |
0 |
0 |
2088405 |
7.3 % |
30/04/2021 |
| Joe Lewis |
Delaware |
0 |
2088405 |
0 |
0 |
2088405 |
7.3 % |
30/04/2021 |
| Aaron I. Davis |
Delaware |
0 |
73186 |
0 |
0 |
73186 |
0.3 % |
30/04/2021 |
| Bihua Chen |
United States |
1606 |
3170872 |
1606 |
3170872 |
3172478 |
11.03 % |
30/04/2021 |
| Cormorant Private Healthcare GP III, LLC |
Delaware |
0 |
1717232 |
0 |
1717232 |
1717232 |
5.97 % |
30/04/2021 |
| Cormorant Asset Management, LP |
Delaware |
0 |
3170872 |
0 |
3170872 |
3170872 |
11.02 % |
30/04/2021 |
| Cormorant Private Healthcare Fund III, LP |
Delaware |
0 |
1717232 |
0 |
1717232 |
1717232 |
5.97 % |
30/04/2021 |
| Cormorant Global Healthcare GP, LLC |
Delaware |
0 |
1395928 |
0 |
1395928 |
1395928 |
4.85 % |
30/04/2021 |
| Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
0 |
1395928 |
0 |
1395928 |
1395928 |
4.85 % |
30/04/2021 |