| Abigail P. Johnson |
United States of America |
0 |
0 |
4773776 |
0 |
4773776 |
9.164 % |
12/11/2024 |
| FMR LLC |
Delaware |
4766119 |
0 |
4773776 |
0 |
4773776 |
9.164 % |
12/11/2024 |
| Morgan Stanley |
Delaware. |
|
704471 |
0 |
708180 |
708180 |
1.4 % |
09/09/2024 |
| Morgan Stanley Capital Services LLC |
Delaware. |
|
701978 |
0 |
701978 |
701978 |
1.3 % |
09/09/2024 |
| JPMORGAN CHASE & |
Delaware |
54003 |
8919 |
125903 |
8919 |
134822 |
0.2 % |
05/09/2024 |
| Millennium Group Management LLC |
Delaware |
0 |
2843128 |
0 |
2843128 |
2843128 |
5.5 % |
23/08/2024 |
| Israel A. Englander |
United States |
0 |
2843128 |
0 |
2843128 |
2843128 |
5.5 % |
23/08/2024 |
| Millennium Management LLC |
Delaware |
0 |
2843128 |
0 |
2843128 |
2843128 |
5.5 % |
23/08/2024 |
| BlackRock, Inc. |
Delaware |
879567 |
0 |
880462 |
0 |
880462 |
1.7 % |
08/07/2024 |
| The Vanguard Group |
Pennsylvania |
0 |
81539 |
3841838 |
99529 |
3941367 |
7.85 % |
13/02/2024 |
| Morgan Stanley Capital Services LLC |
Delaware. |
|
2635864 |
0 |
2635864 |
2635864 |
5.3 % |
09/02/2024 |
| Morgan Stanley |
Delaware. |
|
3359236 |
0 |
3413343 |
3413343 |
6.8 % |
09/02/2024 |
| FMR LLC |
Delaware |
7040849 |
0 |
7066782 |
0 |
7066782 |
14.075 % |
09/02/2024 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
7066782 |
0 |
7066782 |
14.075 % |
09/02/2024 |
| JPMORGAN CHASE & |
Delaware |
4190010 |
8004 |
4737753 |
8004 |
4745757 |
9.4 % |
23/01/2024 |
| JPMORGAN CHASE & |
Delaware |
4472027 |
6245 |
5001859 |
6245 |
5008104 |
10 % |
08/09/2023 |
| T. Rowe Price Investment Management, Inc. |
Maryland |
986709 |
0 |
3519870 |
0 |
3519870 |
7.3 % |
14/02/2023 |
| AllianceBernstein L.P. |
Delaware |
56168 |
0 |
56168 |
0 |
56168 |
0.1 % |
13/02/2023 |
| AllianceBernstein L.P. |
Delaware |
56168 |
0 |
56168 |
0 |
56168 |
0.1 % |
13/02/2023 |
| The Vanguard Group |
Pennsylvania For |
0 |
79136 |
4462810 |
116846 |
4579656 |
9.48 % |
09/02/2023 |
| BlackRock, Inc. |
Delaware |
3453192 |
0 |
3500113 |
0 |
3500113 |
7.2 % |
31/01/2023 |
| JPMORGAN CHASE & |
Delaware |
4180524 |
0 |
4516461 |
0 |
4516694 |
9.3 % |
25/01/2023 |
| AllianceBernstein L.P. |
Delaware |
2531070 |
0 |
2580725 |
33457 |
2614182 |
5.6 % |
14/02/2022 |
| AllianceBernstein L.P. |
Delaware |
2531070 |
0 |
2580725 |
33457 |
2614182 |
5.6 % |
14/02/2022 |
| The Vanguard Group |
Pennsylvania For |
0 |
86603 |
4015184 |
118730 |
4133914 |
8.78 % |
10/02/2022 |
| BlackRock, Inc. |
Delaware |
4495555 |
0 |
4529258 |
0 |
4529258 |
9.6 % |
03/02/2022 |
| JPMORGAN CHASE & |
Delaware |
2408574 |
0 |
2906974 |
0 |
2910874 |
6.1 % |
26/01/2022 |
| Mubadala Investment Company PJSC |
The Emirate of Abu Dhabi, United Arab Emirates |
0 |
1444665 |
0 |
1444665 |
1444665 |
3.1 % |
07/12/2021 |
| Aurora Investment Company LLC |
The Emirate of Abu Dhabi, United Arab Emirates |
0 |
1444665 |
0 |
1444665 |
1444665 |
3.1 % |
07/12/2021 |
| Mubadala Technology Investments |
The Emirate of Abu Dhabi, United Arab Emirates |
0 |
1444665 |
0 |
1444665 |
1444665 |
3.1 % |
07/12/2021 |
| Mamoura Diversified Global Holding PJSC |
The Emirate of Abu Dhabi, United Arab Emirates |
0 |
1444665 |
0 |
1444665 |
1444665 |
3.1 % |
07/12/2021 |
| BlackRock, Inc. |
Delaware |
4791487 |
0 |
4830578 |
0 |
4830578 |
10.4 % |
08/10/2021 |
| T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
285380 |
0 |
1512384 |
0 |
1512384 |
3.2 % |
10/09/2021 |
| T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
285380 |
0 |
1512384 |
0 |
1512384 |
3.2 % |
10/09/2021 |
| PFM Health Sciences GP, LLC |
Delaware |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| PFM Health Sciences, LP |
Delaware |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| PFM Health Sciences GP, LLC |
Delaware |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| Brian D. Grossman |
US |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| PFM Health Sciences, LP |
Delaware |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| Partner Asset Management, LLC |
Delaware |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| Brian D. Grossman |
US |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| Partner Asset Management, LLC |
Delaware |
0 |
2911207 |
0 |
0 |
6 |
6.8 % |
16/02/2021 |
| Perceptive Advisors LLC |
Delaware |
0 |
2847822 |
0 |
2847822 |
2847822 |
6.7 % |
16/02/2021 |
| Joseph Edelman |
United States of America |
0 |
2847822 |
0 |
2847822 |
2847822 |
6.7 % |
16/02/2021 |
| Perceptive Life Sciences Master Fund, Ltd. |
Cayman Islands |
0 |
2847822 |
0 |
2847822 |
2847822 |
6.7 % |
16/02/2021 |
| T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
500302 |
0 |
4658295 |
0 |
4658295 |
10.9 % |
16/02/2021 |
| T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
500302 |
0 |
4658295 |
0 |
4658295 |
10.9 % |
16/02/2021 |
| Daniel Sundheim |
United States America |
0 |
4575754 |
0 |
4575754 |
4575754 |
10.7 % |
16/02/2021 |
| D1 Capital Partners L.P. |
Delaware |
0 |
4575754 |
0 |
4575754 |
4575754 |
10.7 % |
16/02/2021 |
| Warburg Pincus X GP L.P. |
Delaware |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| Warburg Pincus X Partners, L.P. |
Delaware |
0 |
146698 |
0 |
146698 |
146698 |
0.3 % |
12/02/2021 |
| Warburg Pincus Partners GP LLC |
Delaware |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| Warburg Pincus & Co. |
Delaware |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| Warburg Pincus X, L.P. |
Delaware |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| Warburg Pincus Partners, L.P. |
Cayman Islands |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| Warburg Pincus Private Equity X, L.P. |
Delaware |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| Warburg Pincus LLC |
New York |
0 |
4732203 |
0 |
4732203 |
4732203 |
11.1 % |
12/02/2021 |
| Warburg Pincus X Finance, L.P. |
Delaware |
0 |
4585505 |
0 |
4585505 |
4585505 |
10.7 % |
12/02/2021 |
| T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
437196 |
0 |
4579379 |
0 |
4579379 |
10.8 % |
13/10/2020 |
| T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
437196 |
0 |
4579379 |
0 |
4579379 |
10.8 % |
13/10/2020 |
| FMR LLC |
Delaware |
905081 |
0 |
6349244 |
0 |
6349244 |
14.999 % |
13/10/2020 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
6349244 |
0 |
6349244 |
14.999 % |
13/10/2020 |
| FMR LLC |
Delaware |
905081 |
0 |
6349244 |
0 |
6349244 |
14.999 % |
13/10/2020 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
6349244 |
0 |
6349244 |
14.999 % |
13/10/2020 |
| Christopher M. James |
U.S. Citizen |
0 |
2872991 |
0 |
2872991 |
2872991 |
6.8 % |
25/09/2020 |
| Partner Investment Management GP, LLC |
Delaware |
0 |
232514 |
0 |
232514 |
232514 |
0.5 % |
25/09/2020 |
| Partner Fund Management, L.P. |
Delaware |
0 |
2640477 |
0 |
2640477 |
2640477 |
6.2 % |
25/09/2020 |
| Partner Fund Management GP, LLC |
Delaware |
0 |
2640477 |
0 |
2640477 |
2640477 |
6.2 % |
25/09/2020 |
| Partner Investment Management, L.P. |
Delaware |
0 |
232514 |
0 |
232514 |
232514 |
0.5 % |
25/09/2020 |
| Partner Investment Management GP, LLC |
Delaware |
0 |
232514 |
0 |
232514 |
232514 |
0.5 % |
25/09/2020 |
| Brian D. Grossman |
U.S. Citizen |
0 |
2872991 |
0 |
2872991 |
2872991 |
6.8 % |
25/09/2020 |
| Christopher M. James |
U.S. Citizen |
0 |
2872991 |
0 |
2872991 |
2872991 |
6.8 % |
25/09/2020 |
| Partner Fund Management, L.P. |
Delaware |
0 |
2640477 |
0 |
2640477 |
2640477 |
6.2 % |
25/09/2020 |
| Partner Investment Management, L.P. |
Delaware |
0 |
232514 |
0 |
232514 |
232514 |
0.5 % |
25/09/2020 |
| Partner Fund Management GP, LLC |
Delaware |
0 |
2640477 |
0 |
2640477 |
2640477 |
6.2 % |
25/09/2020 |
| Brian D. Grossman |
U.S. Citizen |
0 |
2872991 |
0 |
2872991 |
2872991 |
6.8 % |
25/09/2020 |
