BlackRock, Inc. |
Delaware |
8502170 |
0 |
8787650 |
0 |
8787650 |
10.3 % |
06/12/2024 |
BlackRock, Inc. |
Delaware |
7982348 |
0 |
8239080 |
0 |
8239080 |
9.7 % |
08/11/2024 |
Wellington Group Holdings LLP |
Delaware |
0 |
4636658 |
0 |
4985976 |
4985976 |
5.86 % |
08/11/2024 |
Wellington Management Company LLP |
Delaware |
0 |
4629311 |
0 |
4848463 |
4848463 |
5.7 % |
08/11/2024 |
Wellington Management Group LLP |
Massachusetts |
0 |
4636658 |
0 |
4985976 |
4985976 |
5.86 % |
08/11/2024 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
4636658 |
0 |
4985976 |
4985976 |
5.86 % |
08/11/2024 |
BlackRock, Inc. |
Delaware |
0 |
0 |
8239080 |
0 |
8239080 |
9.7 % |
21/10/2024 |
STATE STREET CORPORATION |
MA |
0 |
3550169 |
0 |
3770826 |
3770826 |
4.4 % |
18/10/2024 |
Kynam Capital Management, LP |
Delaware |
0 |
5660000 |
0 |
5660000 |
5660000 |
6.67 % |
14/02/2024 |
Yue Tang |
U.S. |
0 |
5660000 |
0 |
5660000 |
5660000 |
6.67 % |
14/02/2024 |
Kynam Capital Management GP, LLC |
Delaware |
0 |
5660000 |
0 |
5660000 |
5660000 |
6.67 % |
14/02/2024 |
Point72 Asia |
Singapore |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2024 |
Point72 Middle East FZE |
United Arab Emirates |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2024 |
Point72 Asset Management, L.P. |
Delaware |
0 |
2834499 |
0 |
2834499 |
2834499 |
3.3 % |
14/02/2024 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
2834499 |
0 |
2834499 |
2834499 |
3.3 % |
14/02/2024 |
Cubist Systematic Strategies, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2024 |
Steven A. Cohen |
United States |
0 |
2834499 |
0 |
2834499 |
2834499 |
3.3 % |
14/02/2024 |
The Vanguard Group |
Pennsylvania |
0 |
110826 |
4156966 |
178387 |
4335353 |
5.11 % |
13/02/2024 |
Wellington Management Group LLP |
Massachusetts |
0 |
7231445 |
0 |
7585221 |
7585221 |
8.94 % |
08/02/2024 |
Wellington Group Holdings LLP |
Delaware |
0 |
7231445 |
0 |
7585221 |
7585221 |
8.94 % |
08/02/2024 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
7231445 |
0 |
7585221 |
7585221 |
8.94 % |
08/02/2024 |
Wellington Management Company LLP |
Delaware |
0 |
7186960 |
0 |
7392381 |
7392381 |
8.72 % |
08/02/2024 |
BlackRock, Inc. |
Delaware |
6775465 |
0 |
7015548 |
0 |
7015548 |
8.3 % |
25/01/2024 |
STATE STREET CORPORATION |
BOSTON, MASSACHUSETTS |
0 |
4864846 |
0 |
5016224 |
5016224 |
5.91 % |
25/01/2024 |
Point72 Asset Management, L.P. |
Delaware |
0 |
3156982 |
0 |
3156982 |
3156982 |
4.5 % |
31/10/2023 |
Point72 Middle East FZE |
United Arab Emirates |
0 |
72036 |
0 |
72306 |
72036 |
0.1 % |
31/10/2023 |
Point72 Asia |
Singapore |
0 |
3023 |
0 |
3023 |
3023 |
0.1 % |
31/10/2023 |
Steven A. Cohen |
United States |
0 |
3520402 |
0 |
3520402 |
3520402 |
5.1 % |
31/10/2023 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
3156982 |
0 |
3156982 |
3156982 |
4.5 % |
31/10/2023 |
Point72 Asset Management, L.P. |
Delaware |
0 |
3156982 |
0 |
3156982 |
3156982 |
4.5 % |
31/10/2023 |
Cubist Systematic Strategies, LLC |
Delaware |
0 |
288361 |
0 |
288361 |
288361 |
0.4 % |
31/10/2023 |
Point72 Middle East FZE |
United Arab Emirates |
0 |
72036 |
0 |
72306 |
72036 |
0.1 % |
31/10/2023 |
Point72 Asia |
Singapore |
0 |
3023 |
0 |
3023 |
3023 |
0.1 % |
31/10/2023 |
Steven A. Cohen |
United States |
0 |
3520402 |
0 |
3520402 |
3520402 |
5.1 % |
31/10/2023 |
Cubist Systematic Strategies, LLC |
Delaware |
0 |
288361 |
0 |
288361 |
288361 |
0.4 % |
31/10/2023 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
3156982 |
0 |
3156982 |
3156982 |
4.5 % |
31/10/2023 |
FHMLSP, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences Public Fund, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Daniel Estes |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
James Brush |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Albert Cha |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Patrick J. Heron |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
James N. Topper |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS X, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS X, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences X, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS XI, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS XI, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences XI, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP Overage, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP Overage, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences Public Overage Fund, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences Public Fund, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Daniel Estes |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
James Brush |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Albert Cha |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Patrick J. Heron |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
James N. Topper |
United States Citizen |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS X, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS X, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences X, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS XI, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLS XI, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences XI, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP Overage, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
FHMLSP Overage, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Frazier Life Sciences Public Overage Fund, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
05/10/2023 |
Daniel Mack |
USA |
0 |
975705 |
0 |
975705 |
975705 |
1.4 % |
14/02/2023 |
Wilmot B. Harkey |
USA |
0 |
975705 |
0 |
975705 |
975705 |
1.4 % |
14/02/2023 |
Nantahala Capital Management, LLC |
MA |
0 |
975705 |
0 |
975705 |
975705 |
1.4 % |
14/02/2023 |
Daniel Mack |
USA |
0 |
975705 |
0 |
975705 |
975705 |
1.4 % |
14/02/2023 |
Wilmot B. Harkey |
USA |
0 |
975705 |
0 |
975705 |
975705 |
1.4 % |
14/02/2023 |
Nantahala Capital Management, LLC |
MA |
0 |
975705 |
0 |
975705 |
975705 |
1.4 % |
14/02/2023 |
STATE STREET CORPORATION |
BOSTON, MASSACHUSETTS |
0 |
3545446 |
0 |
3648463 |
3648463 |
5.36 % |
06/02/2023 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
7216510 |
0 |
7983442 |
7983442 |
11.72 % |
10/01/2023 |
Wellington Group Holdings LLP |
Delaware |
0 |
7216510 |
0 |
7983442 |
7983442 |
11.72 % |
10/01/2023 |
Wellington Management Group LLP |
Massachusetts |
0 |
7216510 |
0 |
7983442 |
7983442 |
11.72 % |
10/01/2023 |
Wellington Management Company LLP |
Delaware |
0 |
7192760 |
0 |
7633154 |
7633154 |
11.21 % |
10/01/2023 |
Daniel Mack |
USA |
0 |
3050559 |
0 |
3050559 |
3050559 |
5.8 % |
14/02/2022 |
Wilmot B. Harkey |
USA |
0 |
3050559 |
0 |
3050559 |
3050559 |
5.8 % |
14/02/2022 |
Nantahala Capital Management, LLC |
MA |
0 |
3050559 |
0 |
3050559 |
3050559 |
5.8 % |
14/02/2022 |
Wilmot B. Harkey |
USA |
0 |
3050559 |
0 |
3050559 |
3050559 |
5.8 % |
14/02/2022 |
Nantahala Capital Management, LLC |
MA |
0 |
3050559 |
0 |
3050559 |
3050559 |
5.8 % |
14/02/2022 |
Daniel Mack |
USA |
0 |
3050559 |
0 |
3050559 |
3050559 |
5.8 % |
14/02/2022 |
BlackRock, Inc. |
Delaware |
3630796 |
0 |
3689894 |
0 |
3689894 |
7 % |
07/02/2022 |
Wellington Group Holdings LLP |
Delaware |
0 |
1383678 |
0 |
1598766 |
1598766 |
3.04 % |
04/02/2022 |
Wellington Management Group LLP |
Massachusetts |
0 |
1383678 |
0 |
1598766 |
1598766 |
3.04 % |
04/02/2022 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
1383678 |
0 |
1598766 |
1598766 |
3.04 % |
04/02/2022 |
James N. Topper |
United States Citizen |
0 |
2772062 |
0 |
2772062 |
2772062 |
5.6 % |
23/12/2021 |
FHMLS X, L.P. |
Delaware |
0 |
1188135 |
0 |
1188135 |
1188135 |
2.4 % |
23/12/2021 |
FHMLS X, L.L.C. |
Delaware |
0 |
1188135 |
0 |
1188135 |
1188135 |
2.4 % |
23/12/2021 |
James N. Topper |
United States Citizen |
0 |
2772062 |
0 |
2772062 |
2772062 |
5.6 % |
23/12/2021 |
Patrick J. Heron |
United States Citizen |
0 |
2772062 |
0 |
2772062 |
2772062 |
5.6 % |
23/12/2021 |
Albert Cha |
United States Citizen |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
James Brush |
United States Citizen |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
Frazier Life Sciences Public Fund L.P. |
Delaware |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
FHMLSP, L.P. |
Delaware |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
FHMLSP, L.L.C. |
Delaware |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
Frazier Life Sciences X, L.P. |
Delaware |
0 |
1188135 |
0 |
1188135 |
1188135 |
2.4 % |
23/12/2021 |
FHMLS X, L.P. |
Delaware |
0 |
1188135 |
0 |
1188135 |
1188135 |
2.4 % |
23/12/2021 |
FHMLS X, L.L.C. |
Delaware |
0 |
1188135 |
0 |
1188135 |
1188135 |
2.4 % |
23/12/2021 |
Frazier Life Sciences X, L.P. |
Delaware |
0 |
1188135 |
0 |
1188135 |
1188135 |
2.4 % |
23/12/2021 |
Patrick J. Heron |
United States Citizen |
0 |
2772062 |
0 |
2772062 |
2772062 |
5.6 % |
23/12/2021 |
Albert Cha |
United States Citizen |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
James Brush |
United States Citizen |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
Frazier Life Sciences Public Fund L.P. |
Delaware |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
FHMLSP, L.P. |
Delaware |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
FHMLSP, L.L.C. |
Delaware |
0 |
1583927 |
0 |
1583927 |
1583927 |
3.2 % |
23/12/2021 |
Adage Capital Partners, L.P. |
Delaware |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Robert Atchinson |
United States |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Phillip Gross |
United States |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Adage Capital Partners, L.P. |
Delaware |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Robert Atchinson |
United States |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Phillip Gross |
United States |
0 |
2700000 |
0 |
2700000 |
2700000 |
5.6 % |
10/05/2021 |
Avidity Capital Partners Fund |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Partners Management LP |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Partners Management |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Capital Partners Fund |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Capital Partners |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Master Fund LP |
Cayman Islands |
0 |
3645488 |
0 |
3645488 |
3645488 |
7.6 % |
20/04/2021 |
David Witzke |
United States of America |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Michael Gregory |
United States of America |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Partners Management LP |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Partners Management |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Michael Gregory |
United States of America |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
David Witzke |
United States of America |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Avidity Master Fund LP |
Cayman Islands |
0 |
3645488 |
0 |
3645488 |
3645488 |
7.6 % |
20/04/2021 |
Avidity Capital Partners |
Delaware |
0 |
4750000 |
0 |
4750000 |
4750000 |
9.9 % |
20/04/2021 |
Aaron I. Davis |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2021 |
MVA Investors, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2021 |
Joe Lewis |
United Kingdom |
0 |
2358005 |
0 |
2358005 |
2358005 |
4.99 % |
16/02/2021 |
Boxer Asset Management Inc. |
Bahamas |
0 |
2358005 |
0 |
2358005 |
2358005 |
4.99 % |
16/02/2021 |
Boxer Capital, LLC |
Delaware |
0 |
2358005 |
0 |
2358005 |
2358005 |
4.99 % |
16/02/2021 |
Boxer Capital, LLC |
Delaware |
0 |
2358005 |
0 |
2358005 |
2358005 |
4.99 % |
16/02/2021 |
Boxer Asset Management Inc. |
Bahamas |
0 |
2358005 |
0 |
2358005 |
2358005 |
4.99 % |
16/02/2021 |
Joe Lewis |
United Kingdom |
0 |
2358005 |
0 |
2358005 |
2358005 |
4.99 % |
16/02/2021 |
MVA Investors, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2021 |
Aaron I. Davis |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2021 |
Avidity Partners Management LLC |
Delaware |
0 |
3308000 |
0 |
3308000 |
3308000 |
7.1 % |
16/02/2021 |
David Witzke |
United States America |
0 |
3308000 |
0 |
3308000 |
3308000 |
7.1 % |
16/02/2021 |
Avidity Master Fund LP |
Cayman Islands |
0 |
2955633 |
0 |
2955633 |
2955633 |
6.4 % |
16/02/2021 |
Avidity Capital Partners LLC |
Delaware |
0 |
3308000 |
0 |
3308000 |
3308000 |
7.1 % |
16/02/2021 |
Avidity Capital Partners Fund LP |
Delaware |
0 |
3308000 |
0 |
3308000 |
3308000 |
7.1 % |
16/02/2021 |
Avidity Partners Management LP |
Delaware |
0 |
3308000 |
0 |
3308000 |
3308000 |
7.1 % |
16/02/2021 |
Michael Gregory |
United States America |
0 |
3308000 |
0 |
3308000 |
3308000 |
7.1 % |
16/02/2021 |
Wellington Management Company LLP |
Delaware |
0 |
2361741 |
0 |
2465680 |
2465680 |
5.23 % |
04/02/2021 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2389120 |
0 |
2615443 |
2615443 |
5.54 % |
04/02/2021 |
Wellington Group Holdings LLP |
Delaware |
0 |
2389120 |
0 |
2615443 |
2615443 |
5.54 % |
04/02/2021 |
Wellington Management Group LLP |
Massachusetts |
0 |
2389120 |
0 |
2615443 |
2615443 |
5.54 % |
04/02/2021 |
Len Blavatnik |
United States of America |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
Access Industries Holdings LLC |
State of Delaware |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
AI Life Sciences Investments LLC |
State of Delaware |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
AI Life Sciences Investments LLC |
State of Delaware |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
Access Industries Holdings LLC |
State of Delaware |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
Access Industries Management, LLC |
State of Delaware |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
Len Blavatnik |
United States of America |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
Access Industries Management, LLC |
State of Delaware |
0 |
1888200 |
0 |
2138200 |
2138200 |
4.6 % |
03/02/2021 |
BlackRock, Inc. |
Delaware |
2307402 |
0 |
2320406 |
0 |
2320406 |
5 % |
02/02/2021 |
(Voluntary) Domain Partners VI, L.P. |
|
1162554 |
0 |
1162554 |
0 |
1162554 |
2.5 % |
20/01/2021 |
(Voluntary) Domain Partners VIII, L.P. |
|
737239 |
0 |
737239 |
0 |
737239 |
1.6 % |
20/01/2021 |
(Voluntary) Domain Associates, LLC |
|
13564 |
0 |
13564 |
0 |
13564 |
0.1 % |
20/01/2021 |
(Voluntary) Domain Associates, LLC |
|
13564 |
0 |
13564 |
0 |
13564 |
0.1 % |
20/01/2021 |
(Voluntary) Domain Partners VIII, L.P. |
|
737239 |
0 |
737239 |
0 |
737239 |
1.6 % |
20/01/2021 |
(Voluntary) DP VIII Associates, L.P. |
|
5464 |
0 |
5464 |
0 |
5464 |
0.1 % |
20/01/2021 |
(Voluntary) DP VI Associates, L.P. |
|
9283 |
0 |
9283 |
0 |
9283 |
0.1 % |
20/01/2021 |
(Voluntary) DP VI Associates, L.P. |
|
9283 |
0 |
9283 |
0 |
9283 |
0.1 % |
20/01/2021 |
(Voluntary) Domain Partners VI, L.P. |
|
1162554 |
0 |
1162554 |
0 |
1162554 |
2.5 % |
20/01/2021 |
(Voluntary) DP VIII Associates, L.P. |
|
5464 |
0 |
5464 |
0 |
5464 |
0.1 % |
20/01/2021 |
Wellington Group Holdings LLP |
Delaware |
0 |
2002147 |
0 |
2174223 |
2174223 |
5.32 % |
10/12/2020 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2002147 |
0 |
2174223 |
2174223 |
5.32 % |
10/12/2020 |
Wellington Management Group LLP |
Massachusetts |
0 |
2002147 |
0 |
2174223 |
2174223 |
5.32 % |
10/12/2020 |
Wellington Group Holdings LLP |
Delaware |
0 |
2002147 |
0 |
2174223 |
2174223 |
5.32 % |
10/12/2020 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2002147 |
0 |
2174223 |
2174223 |
5.32 % |
10/12/2020 |
Wellington Management Group LLP |
Massachusetts |
0 |
2002147 |
0 |
2174223 |
2174223 |
5.32 % |
10/12/2020 |
Avidity Master Fund LP |
Cayman Islands |
0 |
2361200 |
0 |
2361200 |
2361200 |
6.1 % |
04/11/2020 |
Michael Gregory |
United States of America |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
David Witzke |
United States of America |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Capital Partners (GP) LLC |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Capital Partners Fund (GP) LP |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Partners Management (GP) LLC |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Partners Management LP |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Michael Gregory |
United States of America |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
David Witzke |
United States of America |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Master Fund LP |
Cayman Islands |
0 |
2361200 |
0 |
2361200 |
2361200 |
6.1 % |
04/11/2020 |
Avidity Capital Partners (GP) LLC |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Capital Partners Fund (GP) LP |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Partners Management (GP) LLC |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
Avidity Partners Management LP |
Delaware |
0 |
2600000 |
0 |
2600000 |
2600000 |
6.7 % |
04/11/2020 |
BlackRock, Inc. |
Delaware |
1796263 |
0 |
1827426 |
0 |
1827426 |
4.7 % |
09/09/2020 |
Joe Lewis |
United Kingdom |
0 |
2763569 |
0 |
2763569 |
2763569 |
7.6 % |
11/05/2020 |
Boxer Asset Management Inc. |
Bahamas |
0 |
2763569 |
0 |
2763569 |
2763569 |
7.6 % |
11/05/2020 |
Boxer Capital, LLC |
Delaware |
0 |
2763569 |
0 |
2763569 |
2763569 |
7.6 % |
11/05/2020 |
Boxer Asset Management Inc. |
Bahamas |
0 |
2763569 |
0 |
2763569 |
2763569 |
7.6 % |
11/05/2020 |
Joe Lewis |
United Kingdom |
0 |
2763569 |
0 |
2763569 |
2763569 |
7.6 % |
11/05/2020 |
MVA Investors, LLC |
Delaware |
48437 |
0 |
48437 |
0 |
48437 |
0.1 % |
11/05/2020 |
Aaron I. Davis |
Delaware |
48437 |
0 |
48437 |
0 |
48437 |
0.1 % |
11/05/2020 |
Boxer Capital, LLC |
Delaware |
0 |
2763569 |
0 |
2763569 |
2763569 |
7.6 % |
11/05/2020 |
MVA Investors, LLC |
Delaware |
48437 |
0 |
48437 |
0 |
48437 |
0.1 % |
11/05/2020 |
Aaron I. Davis |
Delaware |
48437 |
0 |
48437 |
0 |
48437 |
0.1 % |
11/05/2020 |
BVF Inc. |
Delaware |
0 |
2816390 |
0 |
2816390 |
2816390 |
9.99 % |
14/02/2020 |
BVF GP HOLDINGS LLC |
Delaware |
0 |
2722158 |
0 |
2722158 |
2722158 |
9.7 % |
14/02/2020 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
1899545 |
0 |
1899545 |
1899545 |
6.7 % |
14/02/2020 |
BVF I GP LLC |
Delaware |
0 |
1899545 |
0 |
1899545 |
1899545 |
6.7 % |
14/02/2020 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
822613 |
0 |
822613 |
822613 |
3 % |
14/02/2020 |
BVF II GP LLC |
Delaware |
0 |
822613 |
0 |
822613 |
822613 |
3 % |
14/02/2020 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
94232 |
0 |
94232 |
94232 |
1 % |
14/02/2020 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
94232 |
0 |
94232 |
94232 |
1 % |
14/02/2020 |
Mark N. Lampert |
United States |
0 |
2816390 |
0 |
2816390 |
2816390 |
9.99 % |
14/02/2020 |
BVF Partners L.P. |
Delaware |
0 |
2816390 |
0 |
2816390 |
2816390 |
9.99 % |
14/02/2020 |
Access Industries Management, LLC |
State of Delaware |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
AI Life Sciences Investments LLC |
State of Delaware |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
Access Industries Holdings LLC |
State of Delaware |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
Len Blavatnik |
United States of America |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
AI Life Sciences Investments LLC |
State of Delaware |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
Access Industries Holdings LLC |
State of Delaware |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
Access Industries Management, LLC |
State of Delaware |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
Len Blavatnik |
United States of America |
0 |
2888200 |
0 |
3028742 |
3028742 |
9.9 % |
14/02/2020 |
Ari Zweiman |
United States America |
0 |
1153373 |
0 |
1153373 |
1153373 |
4.2 % |
13/02/2020 |
Capital Management, LLC |
Delaware |
0 |
1153373 |
0 |
1153373 |
1153373 |
4.2 % |
13/02/2020 |
Capital Partners, LP |
Delaware |
0 |
1153373 |
0 |
1153373 |
1153373 |
4.2 % |
13/02/2020 |
Ari Zweiman |
United States America |
0 |
1153373 |
0 |
1153373 |
1153373 |
4.2 % |
13/02/2020 |
Capital Management, LLC |
Delaware |
0 |
1153373 |
0 |
1153373 |
1153373 |
4.2 % |
13/02/2020 |
Capital Partners, LP |
Delaware |
0 |
1153373 |
0 |
1153373 |
1153373 |
4.2 % |
13/02/2020 |
Robert Atchinson |
United States |
0 |
1250000 |
0 |
1250000 |
1250000 |
4.61 % |
12/02/2020 |
Adage Capital Partners, L.P. |
Delaware |
0 |
1250000 |
0 |
1250000 |
1250000 |
4.61 % |
12/02/2020 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
1250000 |
0 |
1250000 |
1250000 |
4.61 % |
12/02/2020 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
1250000 |
0 |
1250000 |
1250000 |
4.61 % |
12/02/2020 |
Phillip Gross |
United States |
0 |
1250000 |
0 |
1250000 |
1250000 |
4.61 % |
12/02/2020 |
Wellington Management Company LLP |
Delaware |
0 |
2771892 |
0 |
2878160 |
2878160 |
10.6 % |
28/01/2020 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2799170 |
0 |
3043690 |
3043690 |
11.21 % |
28/01/2020 |
Wellington Group Holdings LLP |
Delaware |
0 |
2799170 |
0 |
3043690 |
3043690 |
11.21 % |
28/01/2020 |
Wellington Management Group LLP |
Massachusetts |
0 |
2799170 |
0 |
3043690 |
3043690 |
11.21 % |
28/01/2020 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2799170 |
0 |
3043690 |
3043690 |
11.21 % |
28/01/2020 |
Wellington Management Company LLP |
Delaware |
0 |
2771892 |
0 |
2878160 |
2878160 |
10.6 % |
28/01/2020 |
Wellington Group Holdings LLP |
Delaware |
0 |
2799170 |
0 |
3043690 |
3043690 |
11.21 % |
28/01/2020 |
Wellington Management Group LLP |
Massachusetts |
0 |
2799170 |
0 |
3043690 |
3043690 |
11.21 % |
28/01/2020 |
AI Life Sciences Investments LLC |
State of Delaware |
1657948 |
0 |
1657948 |
0 |
1657948 |
6.1 % |
09/10/2019 |
Len Blavatnik |
United States of America |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
AI Life Sciences Investments LLC |
State of Delaware |
1657948 |
0 |
1657948 |
0 |
1657948 |
6.1 % |
09/10/2019 |
AI LLC |
State of Delaware |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Access Industries Holdings LLC |
State of Delaware |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Access Industries Holdings (BVI) L.P. |
British Virgin Islands |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Access Industries, LLC |
State of Delaware |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Len Blavatnik |
United States of America |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Access Industries, LLC |
State of Delaware |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Access Industries Holdings (BVI) L.P. |
British Virgin Islands |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Access Industries Holdings LLC |
State of Delaware |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
AI LLC |
State of Delaware |
0 |
1657948 |
0 |
1657948 |
1657948 |
6.1 % |
09/10/2019 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Adage Capital Partners, L.P. |
Delaware |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Phillip Gross |
United States |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Robert Atchinson |
United States |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Phillip Gross |
United States |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Adage Capital Partners, L.P. |
Delaware |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Robert Atchinson |
United States |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
1550000 |
0 |
1550000 |
1550000 |
5.72 % |
08/04/2019 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
1396148 |
0 |
1396148 |
1396148 |
5.5 % |
14/02/2019 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
822613 |
0 |
822613 |
822613 |
3.3 % |
14/02/2019 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
94232 |
0 |
94232 |
94232 |
0 % |
14/02/2019 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
94232 |
0 |
94232 |
94232 |
0 % |
14/02/2019 |
BVF Partners L.P. |
Delaware |
0 |
2535878 |
0 |
2535878 |
2535878 |
9.99 % |
14/02/2019 |
BVF Inc. |
Delaware |
0 |
2535878 |
0 |
2535878 |
2535878 |
9.99 % |
14/02/2019 |
Mark N. Lampert |
United States |
0 |
2535878 |
0 |
2535878 |
2535878 |
9.99 % |
14/02/2019 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
1396148 |
0 |
1396148 |
1396148 |
5.5 % |
14/02/2019 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
822613 |
0 |
822613 |
822613 |
3.3 % |
14/02/2019 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
94232 |
0 |
94232 |
94232 |
0 % |
14/02/2019 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
94232 |
0 |
94232 |
94232 |
0 % |
14/02/2019 |
Mark N. Lampert |
United States |
0 |
2535878 |
0 |
2535878 |
2535878 |
9.99 % |
14/02/2019 |
BVF Inc. |
Delaware |
0 |
2535878 |
0 |
2535878 |
2535878 |
9.99 % |
14/02/2019 |
BVF Partners L.P. |
Delaware |
0 |
2535878 |
0 |
2535878 |
2535878 |
9.99 % |
14/02/2019 |
Ari Zweiman |
United States of America |
0 |
1342839 |
0 |
1342839 |
1342839 |
5.4 % |
14/02/2019 |
683 Capital Partners, LP |
Delaware |
0 |
1342839 |
0 |
1342839 |
1342839 |
5.4 % |
14/02/2019 |
683 Capital Management, LLC |
Delaware |
0 |
1342839 |
0 |
1342839 |
1342839 |
5.4 % |
14/02/2019 |
BlackRock, Inc. |
Delaware |
1536930 |
0 |
1574931 |
0 |
1574931 |
6.3 % |
07/02/2019 |
683 CAPITAL PARTNERS, LP |
DELAWARE |
0 |
1245000 |
0 |
1245000 |
1245000 |
5 % |
29/11/2018 |
683 CAPITAL MANAGEMENT, LLC |
DELAWARE |
0 |
1245000 |
0 |
1245000 |
1245000 |
5 % |
29/11/2018 |
ARI ZWEIMAN |
UNITED STATES |
0 |
1245000 |
0 |
1245000 |
1245000 |
5 % |
29/11/2018 |
683 CAPITAL PARTNERS, LP |
DELAWARE |
0 |
1245000 |
0 |
1245000 |
1245000 |
5 % |
29/11/2018 |
683 CAPITAL MANAGEMENT, LLC |
DELAWARE |
0 |
1245000 |
0 |
1245000 |
1245000 |
5 % |
29/11/2018 |
ARI ZWEIMAN |
UNITED STATES |
0 |
1245000 |
0 |
1245000 |
1245000 |
5 % |
29/11/2018 |
Wellington Group Holdings LLP |
Delaware |
0 |
2995329 |
0 |
3414590 |
3414590 |
14 % |
08/02/2018 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2995329 |
0 |
3414590 |
3414590 |
14 % |
08/02/2018 |
Wellington Management Group LLP |
Massachusetts |
0 |
2995329 |
0 |
3414590 |
3414590 |
14 % |
08/02/2018 |
Wellington Management Company LLP |
Delaware |
0 |
2968051 |
0 |
3243579 |
3243579 |
13.3 % |
08/02/2018 |
MPM BioVentures IV GmbH & Co. Beteiligungs KG |
Germany |
69600 |
0 |
69600 |
0 |
69600 |
0.3 % |
02/02/2018 |
Todd Foley |
United States |
0 |
2168691 |
0 |
2168691 |
2168691 |
8.9 % |
02/02/2018 |
Ansbert Gadicke |
United States |
0 |
2168691 |
0 |
2168691 |
2168691 |
8.9 % |
02/02/2018 |
MPM BioVentures IV Strategic Fund, L.P. |
Delaware |
240963 |
0 |
240963 |
0 |
240963 |
1 % |
02/02/2018 |
MPM BioVentures IV GP LLC |
Delaware |
0 |
2117322 |
0 |
2117322 |
2117322 |
8.7 % |
02/02/2018 |
MPM Asset Management Investors BV4 LLC |
Delaware |
51369 |
0 |
51369 |
0 |
51369 |
0.2 % |
02/02/2018 |
MPM BioVentures IV LLC |
Delaware |
0 |
2168691 |
0 |
2168691 |
2168691 |
8.9 % |
02/02/2018 |
Luke Evnin |
United States |
30064 |
2168691 |
30064 |
2168691 |
2198755 |
9 % |
02/02/2018 |
MPM BioVentures L.P. |
Delaware |
1806759 |
0 |
1806759 |
0 |
1806759 |
7.4 % |
02/02/2018 |
Abigail P. Johnson |
United States of America |
0 |
0 |
727344 |
0 |
727344 |
2.982 % |
11/12/2017 |
Abigail P. Johnson |
United States of America |
0 |
0 |
727344 |
0 |
727344 |
2.982 % |
11/12/2017 |
FMR LLC |
Delaware |
0 |
0 |
727344 |
0 |
727344 |
2.982 % |
11/12/2017 |
FMR LLC |
Delaware |
0 |
0 |
727344 |
0 |
727344 |
2.982 % |
11/12/2017 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
213980 |
0 |
213980 |
213980 |
0 % |
17/11/2017 |
Mark N. Lampert |
United States |
0 |
2547318 |
0 |
2547318 |
2547318 |
10.4 % |
17/11/2017 |
BVF Inc. |
Delaware |
0 |
2547318 |
0 |
2547318 |
2547318 |
10.4 % |
17/11/2017 |
BVF Partners L.P. |
Delaware |
0 |
2547318 |
0 |
2547318 |
2547318 |
10.4 % |
17/11/2017 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
213980 |
0 |
213980 |
213980 |
0 % |
17/11/2017 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
800788 |
0 |
800788 |
800788 |
3.3 % |
17/11/2017 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
1255452 |
0 |
1255452 |
1255452 |
5.1 % |
17/11/2017 |
Mark N. Lampert |
United States |
0 |
2547318 |
0 |
2547318 |
2547318 |
10.4 % |
17/11/2017 |
BVF Inc. |
Delaware |
0 |
2547318 |
0 |
2547318 |
2547318 |
10.4 % |
17/11/2017 |
BVF Partners L.P. |
Delaware |
0 |
2547318 |
0 |
2547318 |
2547318 |
10.4 % |
17/11/2017 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
213980 |
0 |
213980 |
213980 |
0 % |
17/11/2017 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
213980 |
0 |
213980 |
213980 |
0 % |
17/11/2017 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
800788 |
0 |
800788 |
800788 |
3.3 % |
17/11/2017 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
1255452 |
0 |
1255452 |
1255452 |
5.1 % |
17/11/2017 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
947350 |
0 |
947350 |
947350 |
3.9 % |
13/11/2017 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
169388 |
0 |
169388 |
169388 |
0 % |
13/11/2017 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
169388 |
0 |
169388 |
169388 |
0 % |
13/11/2017 |
BVF Partners L.P. |
Delaware |
0 |
2021018 |
0 |
2021018 |
2021018 |
8.3 % |
13/11/2017 |
BVF Inc. |
Delaware |
0 |
2021018 |
0 |
2021018 |
2021018 |
8.3 % |
13/11/2017 |
Mark N. Lampert |
United States |
0 |
2021018 |
0 |
2021018 |
2021018 |
8.3 % |
13/11/2017 |
Biotechnology Value Fund, L.P. |
Delaware |
0 |
947350 |
0 |
947350 |
947350 |
3.9 % |
13/11/2017 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
629906 |
0 |
629906 |
629906 |
2.6 % |
13/11/2017 |
Biotechnology Value Trading Fund OS LP |
Cayman Islands |
0 |
169388 |
0 |
169388 |
169388 |
0 % |
13/11/2017 |
BVF Partners OS Ltd. |
Cayman Islands |
0 |
169388 |
0 |
169388 |
169388 |
0 % |
13/11/2017 |
Mark N. Lampert |
United States |
0 |
2021018 |
0 |
2021018 |
2021018 |
8.3 % |
13/11/2017 |
Biotechnology Value Fund II, L.P. |
Delaware |
0 |
629906 |
0 |
629906 |
629906 |
2.6 % |
13/11/2017 |
BVF Inc. |
Delaware |
0 |
2021018 |
0 |
2021018 |
2021018 |
8.3 % |
13/11/2017 |
BVF Partners L.P. |
Delaware |
0 |
2021018 |
0 |
2021018 |
2021018 |
8.3 % |
13/11/2017 |
Luke Evnin |
United States |
15610 |
2168691 |
15610 |
2168691 |
2184301 |
12 % |
09/02/2017 |
MPM BioVentures IV GP LLC |
Delaware |
0 |
2117322 |
0 |
2117322 |
2117322 |
11.6 % |
09/02/2017 |
MPM BioVentures IV Strategic Fund, L.P. |
Delaware |
240963 |
0 |
240963 |
0 |
240963 |
1.3 % |
09/02/2017 |
MPM Asset Management Investors BV4 LLC |
Delaware |
51369 |
0 |
51369 |
0 |
51369 |
0.3 % |
09/02/2017 |
MPM BioVentures IV GmbH & Co. Beteiligungs KG |
Germany |
69600 |
0 |
69600 |
0 |
69600 |
0.4 % |
09/02/2017 |
MPM BioVentures IVQP, L.P. |
Delaware |
1806759 |
0 |
1806759 |
0 |
1806759 |
9.9 % |
09/02/2017 |
Todd Foley |
United States |
0 |
2168691 |
0 |
2168691 |
2168691 |
11.9 % |
09/02/2017 |
Ansbert Gadicke |
United States |
0 |
2168691 |
0 |
2168691 |
2168691 |
11.9 % |
09/02/2017 |
MPM BioVentures IV LLC |
Delaware |
0 |
2168691 |
0 |
2168691 |
2168691 |
11.9 % |
09/02/2017 |
Wellington Management Company LLP |
Delaware |
0 |
2004749 |
0 |
2234409 |
2234409 |
12.28 % |
09/02/2017 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
2036069 |
0 |
2344648 |
2344648 |
12.89 % |
09/02/2017 |
Wellington Group Holdings LLP |
Delaware |
0 |
2036069 |
0 |
2344648 |
2344648 |
12.89 % |
09/02/2017 |
Wellington Management Group LLP |
Massachusetts |
0 |
2036069 |
0 |
2344648 |
2344648 |
12.89 % |
09/02/2017 |
(Voluntary) Domain Partners VIII, L.P. |
Delaware |
761062 |
0 |
761062 |
0 |
761062 |
4.2 % |
09/01/2017 |
(Voluntary) Domain Associates, LLC |
Delaware |
13564 |
0 |
13564 |
0 |
13564 |
0.1 % |
09/01/2017 |
(Voluntary) DP VI Associates, L.P. |
Delaware |
13925 |
0 |
13925 |
0 |
13925 |
0.1 % |
09/01/2017 |
(Voluntary) Domain Partners VI, L.P. |
Delaware |
1743854 |
0 |
1743854 |
0 |
1743854 |
9.6 % |
09/01/2017 |
(Voluntary) DP VIII Associates, L.P. |
Delaware |
5641 |
0 |
5641 |
0 |
5641 |
0.1 % |
09/01/2017 |
(Voluntary) Domain Partners VIII, L.P. |
Delaware |
761062 |
0 |
761062 |
0 |
761062 |
4.2 % |
09/01/2017 |
(Voluntary) Domain Associates, LLC |
Delaware |
13564 |
0 |
13564 |
0 |
13564 |
0.1 % |
09/01/2017 |
(Voluntary) DP VI Associates, L.P. |
Delaware |
13925 |
0 |
13925 |
0 |
13925 |
0.1 % |
09/01/2017 |
(Voluntary) Domain Partners VI, L.P. |
Delaware |
1743854 |
0 |
1743854 |
0 |
1743854 |
9.6 % |
09/01/2017 |
(Voluntary) DP VIII Associates, L.P. |
Delaware |
5641 |
0 |
5641 |
0 |
5641 |
0.1 % |
09/01/2017 |
Wellington Management Company LLP |
Delaware |
0 |
1681638 |
0 |
1861038 |
1861038 |
10.47 % |
12/09/2016 |
Wellington Management Group LLP |
Massachusetts |
0 |
1708158 |
0 |
1956236 |
1956236 |
11 % |
12/09/2016 |
Wellington Group Holdings LLP |
Delaware |
0 |
1708158 |
0 |
1956236 |
1956236 |
11 % |
12/09/2016 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
1708158 |
0 |
1956236 |
1956236 |
11 % |
12/09/2016 |
Wellington Management Company LLP |
Delaware |
0 |
1681638 |
0 |
1861038 |
1861038 |
10.47 % |
12/09/2016 |
Wellington Management Group LLP |
Massachusetts |
0 |
1708158 |
0 |
1956236 |
1956236 |
11 % |
12/09/2016 |
Wellington Group Holdings LLP |
Delaware |
0 |
1708158 |
0 |
1956236 |
1956236 |
11 % |
12/09/2016 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
1708158 |
0 |
1956236 |
1956236 |
11 % |
12/09/2016 |
Select Biotechnology Portfolio |
Massachusetts |
1682317 |
0 |
0 |
0 |
1682317 |
9.683 % |
11/04/2016 |
FMR LLC |
Delaware |
0 |
0 |
2094464 |
0 |
2094464 |
12.056 % |
11/04/2016 |
Abigail P. Johnson |
United States of America |
0 |
0 |
2094464 |
0 |
2094464 |
12.056 % |
11/04/2016 |
Select Biotechnology Portfolio |
Massachusetts |
1682317 |
0 |
0 |
0 |
1682317 |
9.683 % |
11/04/2016 |
FMR LLC |
Delaware |
0 |
0 |
2094464 |
0 |
2094464 |
12.056 % |
11/04/2016 |
Abigail P. Johnson |
United States of America |
0 |
0 |
2094464 |
0 |
2094464 |
12.056 % |
11/04/2016 |