| Artisan Partners Limited Partnership |
Delaware |
0 |
3989427 |
0 |
5022832 |
5022832 |
6.5 % |
12/11/2024 |
| Artisan Partners Asset Management Inc. |
Delaware |
0 |
3989427 |
0 |
5022832 |
5022832 |
6.5 % |
12/11/2024 |
| Artisan Partners Holdings LP |
Delaware |
0 |
3989427 |
0 |
5022832 |
5022832 |
6.5 % |
12/11/2024 |
| Artisan Investments GP LLC |
Delaware |
0 |
3989427 |
0 |
5022832 |
5022832 |
6.5 % |
12/11/2024 |
| STATE STREET CORPORATION |
BOSTON, MASSACHUSETTS |
0 |
4008404 |
0 |
4159331 |
4159331 |
5.8 % |
06/02/2023 |
| Nikko Asset Management Americas, Inc. |
USA |
0 |
2665030 |
0 |
3121103 |
3121103 |
4.39 % |
14/02/2022 |
| 98-0557567 |
Bermuda |
3869070 |
0 |
4114031 |
0 |
4114031 |
5.8 % |
10/02/2022 |
| The Vanguard Group - 23-1945930 |
Pennsylvania For |
0 |
56320 |
6477098 |
118246 |
6595344 |
9.28 % |
10/02/2022 |
| Wellington Management Group LLP |
Delaware |
0 |
4471892 |
0 |
0 |
5078827 |
7.15 % |
04/02/2022 |
| Wellington Group Holdings LLP |
Delaware |
0 |
4471892 |
0 |
0 |
5078827 |
7.15 % |
04/02/2022 |
| Wellington Management Company LLP |
Delaware |
0 |
4438689 |
0 |
0 |
4813974 |
6.78 % |
04/02/2022 |
| Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
4471892 |
0 |
0 |
5078827 |
7.15 % |
04/02/2022 |
| Artisan Partners Asset Management Inc. |
Delaware |
0 |
4135905 |
0 |
4956409 |
4956409 |
7 % |
04/02/2022 |
| Artisan Partners Holdings LP |
Delaware |
0 |
4135905 |
0 |
4956409 |
4956409 |
7 % |
04/02/2022 |
| Artisan Investments GP LLC |
Delaware |
0 |
4135905 |
0 |
4956409 |
4956409 |
7 % |
04/02/2022 |
| Artisan Partners Limited Partnership |
Delaware |
0 |
4135905 |
0 |
4956409 |
4956409 |
7 % |
04/02/2022 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) |
Japan |
0 |
3121103 |
0 |
3121103 |
3121103 |
4.39 % |
04/02/2022 |
| (1) BlackRock, Inc. |
Delaware |
6038959 |
0 |
6273553 |
0 |
6273553 |
8.8 % |
03/02/2022 |
| 98-0557567 |
Bermuda |
3343814 |
0 |
3567585 |
0 |
3567585 |
6.2 % |
12/02/2021 |
| Artisan Partners Limited Partnership |
Delaware |
0 |
2951433 |
0 |
3529626 |
3529626 |
6.1 % |
10/02/2021 |
| Artisan Partners Holdings LP |
Delaware |
0 |
2951433 |
0 |
3529626 |
3529626 |
6.1 % |
10/02/2021 |
| Artisan Investments GP LLC |
Delaware |
0 |
2951433 |
0 |
3529626 |
3529626 |
6.1 % |
10/02/2021 |
| Artisan Partners Asset Management Inc. |
Delaware |
0 |
2951433 |
0 |
3529626 |
3529626 |
6.1 % |
10/02/2021 |
| (1) BlackRock, Inc. |
Delaware |
5131228 |
0 |
5280975 |
0 |
5280975 |
9.1 % |
01/02/2021 |
| Gilder, Gagnon, Howe & Co. LLC |
New York |
0 |
0 |
0 |
3772602 |
3772602 |
7.72 % |
14/02/2020 |
| Group Holdings (SBS) Advisors, Inc. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
13/02/2020 |
| Bonderman |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
13/02/2020 |
| G. Coulter |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
13/02/2020 |
| 98-0557567 |
Bermuda |
3110897 |
0 |
3337889 |
0 |
3337889 |
6.8 % |
13/02/2020 |
| Nikko Asset Management Americas, Inc. |
USA |
0 |
2095684 |
0 |
3053251 |
3053251 |
6.25 % |
12/02/2020 |
| Nikko Asset Management Co., Ltd. (“NAM”) |
Japan |
0 |
3053251 |
0 |
0 |
3053251 |
6.25 % |
12/02/2020 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) |
Japan |
0 |
3053251 |
0 |
0 |
3053251 |
6.25 % |
12/02/2020 |
| The Vanguard Group - 23-1945930 |
Pennsylvania |
98617 |
0 |
0 |
96784 |
2668494 |
5.46 % |
11/02/2020 |
| William Blair Investment Management, LLC |
Delaware |
3243225 |
0 |
3569401 |
0 |
3569401 |
7.3 % |
10/02/2020 |
| 94-3366999 |
Wyoming, USA |
0 |
1696386 |
0 |
0 |
1696386 |
4.2 % |
14/02/2019 |
| J. Carlo Cannell |
USA |
0 |
1696386 |
0 |
0 |
1696386 |
4.2 % |
14/02/2019 |
| CAPITAL PARTNERS LLC 45-2817402 |
OF DELAWARE |
442500 |
0 |
442500 |
0 |
442500 |
1.1 % |
13/02/2019 |
| (1) BlackRock, Inc. |
Delaware |
2805057 |
0 |
2981669 |
0 |
2981669 |
7.4 % |
06/02/2019 |
| J. Carlo Cannell |
USA |
0 |
1912627 |
0 |
0 |
1912627 |
5.6 % |
14/02/2018 |
| 94-3366999 |
Wyoming, USA |
0 |
1912627 |
0 |
0 |
1912627 |
5.6 % |
14/02/2018 |
| CAPITAL PARTNERS LLC 45-2817402 |
OF DELAWARE |
3295111 |
0 |
3295111 |
0 |
3295111 |
9.7 % |
13/02/2018 |
| (1) BlackRock, Inc. |
Delaware |
1816458 |
0 |
1842981 |
0 |
1842981 |
5.4 % |
01/02/2018 |
| S |
NUMBER OF |
3513161 |
0 |
3513161 |
0 |
3513161 |
10.7 % |
13/02/2017 |
| Broadfin Capital, LLC |
Cayman Islands |
0 |
1916666 |
0 |
1916666 |
1916666 |
5.83 % |
04/11/2016 |
| Kevin Kotler |
Cayman Islands |
0 |
1916666 |
0 |
1916666 |
1916666 |
5.83 % |
04/11/2016 |
| Broadfin Healthcare Master Fund, Ltd. |
Cayman Islands |
0 |
1916666 |
0 |
1916666 |
1916666 |
5.83 % |
04/11/2016 |
| CAPITAL PARTNERS LLC 45-2817402 |
STATE OF DELAWARE |
2885000 |
0 |
2885000 |
0 |
2885000 |
10.4 % |
06/05/2016 |
| CAPITAL PARTNERS LLC 45-2817402 |
OF DELAWARE |
1716000 |
0 |
1716000 |
0 |
1716000 |
6.2 % |
12/02/2016 |
| 2. |
UNITED STATES |
0 |
1439036 |
0 |
1439036 |
1439036 |
5.24 % |
01/06/2015 |
| 2. |
UNITED STATES |
0 |
1439036 |
0 |
1439036 |
1439036 |
5.24 % |
01/06/2015 |
| 2. |
UNITED STATES |
0 |
1439036 |
0 |
1439036 |
1439036 |
5.24 % |
01/06/2015 |
| 2. |
UNITED STATES |
0 |
1439036 |
0 |
1439036 |
1439036 |
5.24 % |
01/06/2015 |
| 2. |
UNITED STATES |
0 |
1439036 |
0 |
1439036 |
1439036 |
5.24 % |
01/06/2015 |
| 26-2508416 |
Delaware |
1384100 |
0 |
1384100 |
0 |
1384100 |
6.2 % |
13/02/2015 |
| Kleiner Perkins Caufield & Byers XII, LLC (“KPCB XII”) |
Delaware |
45695 |
45695 |
45695 |
45695 |
3174484 |
15.1 % |
14/02/2014 |
| David Bonderman |
United States |
0 |
3551929 |
0 |
0 |
3551929 |
16.9 % |
13/02/2014 |
| James G. Coulter |
United States |
0 |
3551929 |
0 |
0 |
3551929 |
16.9 % |
13/02/2014 |
| TPG Group Holdings (SBS) Advisors, Inc. |
Delaware |
0 |
3551929 |
0 |
0 |
3551929 |
16.9 % |
13/02/2014 |