Steven A. Cohen |
United States |
0 |
23974 |
0 |
23974 |
23974 |
0.1 % |
14/11/2024 |
Point72 Asset Management, L.P. |
Delaware |
0 |
23974 |
0 |
23974 |
23974 |
0.1 % |
14/11/2024 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
23974 |
0 |
23974 |
23974 |
0.1 % |
14/11/2024 |
Cubist Systematic Strategies, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/11/2024 |
David Kroin |
United States |
0 |
0 |
0 |
0 |
0 |
0 % |
14/11/2024 |
Deep Track Capital, LP |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/11/2024 |
Deep Track Biotechnology Master Fund, Ltd. |
Cayman Islands |
0 |
0 |
0 |
0 |
0 |
0 % |
14/11/2024 |
BlackRock, Inc. |
Delaware |
1554744 |
0 |
1580548 |
0 |
1580548 |
7.3 % |
08/11/2024 |
BlackRock, Inc. |
Delaware |
0 |
0 |
1580548 |
0 |
1580548 |
7.3 % |
22/10/2024 |
The Vanguard Group |
Pennsylvania |
0 |
11964 |
2131421 |
18436 |
2149857 |
10.24 % |
10/06/2024 |
Cubist Systematic Strategies, LLC |
Delaware |
0 |
388 |
0 |
388 |
388 |
0.1 % |
21/02/2024 |
Steven A. Cohen |
United States |
0 |
28268500 |
0 |
28268500 |
28268500 |
6.8 % |
21/02/2024 |
Point72 Asset Management, L.P. |
Delaware |
0 |
28268112 |
0 |
28268112 |
28268112 |
6.8 % |
21/02/2024 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
28268112 |
0 |
28268112 |
28268112 |
6.8 % |
21/02/2024 |
David Kroin |
United States |
0 |
31697539 |
0 |
31697539 |
0 |
8.31 % |
14/02/2024 |
Deep Track Capital, LP |
Delaware |
0 |
31697539 |
0 |
31697539 |
0 |
8.31 % |
14/02/2024 |
Deep Track Biotechnology Master Fund, Ltd. |
Cayman Islands |
0 |
31697539 |
0 |
31697539 |
0 |
8.31 % |
14/02/2024 |
The Vanguard Group |
Pennsylvania |
0 |
295673 |
29669195 |
597695 |
30266890 |
7.93 % |
13/02/2024 |
Mr. Amaury Wittouck |
Belgium |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Westend S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Stichting Administratiekantoor Westend |
The Netherlands |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Mr. Amaury Wittouck |
Belgium |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Invus Public Equities, L.P. |
Bermuda |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Invus Public Equities Advisors, LLC |
Delaware |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Artal International S.C.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Stichting Administratiekantoor Westend |
The Netherlands |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Westend S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Artal Group S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Artal International Management S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Artal International S.C.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Invus Public Equities Advisors, LLC |
Delaware |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Invus Public Equities, L.P. |
Bermuda |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Artal International Management S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
Artal Group S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
4.1 % |
09/02/2024 |
BlackRock, Inc. |
Delaware |
31472393 |
0 |
32236488 |
0 |
32236488 |
8.5 % |
25/01/2024 |
STATE STREET CORPORATION |
BOSTON, MASSACHUSETTS |
0 |
7166784 |
0 |
8680267 |
8680267 |
2.28 % |
22/01/2024 |
The Vanguard Group |
Pennsylvania |
0 |
509391 |
23540495 |
740760 |
24281255 |
7.97 % |
09/02/2023 |
BlackRock, Inc. |
Delaware |
22717552 |
0 |
23400423 |
0 |
23400423 |
8.3 % |
03/02/2023 |
Invus Public Equities Advisors, LLC |
Delaware |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Mr. Amaury Wittouck |
Belgium |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Stichting Administratiekantoor Westend |
The Netherlands |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Westend S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Artal Group S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Artal International Management S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Artal International S.C.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Invus Public Equities, L.P. |
Bermuda |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Invus Public Equities, L.P. |
Bermuda |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Invus Public Equities Advisors, LLC |
Delaware |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Artal International S.C.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Artal International Management S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Artal Group S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Westend S.A. |
Luxembourg |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Stichting Administratiekantoor Westend |
The Netherlands |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
Mr. Amaury Wittouck |
Belgium |
15631235 |
0 |
15631235 |
0 |
15631235 |
5.1 % |
01/02/2023 |
David Kroin |
United States |
0 |
15229187 |
0 |
15229187 |
0 |
5.92 % |
08/04/2022 |
Deep Track Biotechnology Master Fund, Ltd. |
Cayman Islands |
0 |
15229187 |
0 |
15229187 |
0 |
5.92 % |
08/04/2022 |
Deep Track Capital, LP |
Delaware |
0 |
15229187 |
0 |
15229187 |
0 |
5.92 % |
08/04/2022 |
Deep Track Biotechnology Master Fund, Ltd. |
Cayman Islands |
0 |
15229187 |
0 |
15229187 |
0 |
5.92 % |
08/04/2022 |
David Kroin |
United States |
0 |
15229187 |
0 |
15229187 |
0 |
5.92 % |
08/04/2022 |
Deep Track Capital, LP |
Delaware |
0 |
15229187 |
0 |
15229187 |
0 |
5.92 % |
08/04/2022 |
Gilead Sciences, Inc. |
State of Delaware |
11111111 |
0 |
11111111 |
0 |
11111111 |
4.3 % |
17/02/2022 |
RTW Investments, LP |
Delaware |
0 |
5868315 |
0 |
5868315 |
5868315 |
2.3 % |
14/02/2022 |
Roderick Wong |
United States |
0 |
5868315 |
0 |
5868315 |
5868315 |
2.3 % |
14/02/2022 |
Oracle Associates, LLC |
Delaware |
0 |
8138272 |
0 |
8138272 |
8138272 |
3.17 % |
11/02/2022 |
The Feinberg Family Foundation |
Connecticut |
0 |
62000 |
0 |
62000 |
62000 |
0.02 % |
11/02/2022 |
Oracle Investment Management, Inc. Employees’ Retirement Plan |
Delaware |
0 |
278000 |
0 |
278000 |
278000 |
0.11 % |
11/02/2022 |
Oracle Investment Management, Inc. |
Delaware |
0 |
8416272 |
0 |
8416272 |
8416272 |
3.28 % |
11/02/2022 |
Oracle Ten Fund, L.P. |
Delaware |
0 |
1400010 |
0 |
1400010 |
1400010 |
0.55 % |
11/02/2022 |
Oracle Institutional Partners, L.P. |
Delaware |
0 |
845544 |
0 |
845544 |
845544 |
0.33 % |
11/02/2022 |
Oracle Partners, L.P. |
Delaware |
0 |
5892718 |
0 |
5892718 |
5892718 |
2.29 % |
11/02/2022 |
Larry N. Feinberg |
United States |
627860 |
8478272 |
627860 |
8478272 |
9106132 |
3.55 % |
11/02/2022 |
Incyte Corporation |
|
|
|
|
|
12070195 |
4.7 % |
11/02/2022 |
Incyte Corporation |
|
|
|
|
|
12070195 |
4.7 % |
11/02/2022 |
STATE STREET CORPORATION NO. OF THE ABOVE PERSON: |
BOSTON MASSACHUSETTS |
0 |
20790261 |
0 |
21170850 |
21170850 |
8.24 % |
11/02/2022 |
SSGA FUNDS MANAGEMENT, INC. NO. OF THE ABOVE PERSON: |
BOSTON MASSACHUSETTS |
0 |
17255243 |
0 |
17312543 |
17312543 |
6.74 % |
11/02/2022 |
Gilead Sciences, Inc. |
Delaware |
11111111 |
0 |
11111111 |
0 |
11111111 |
4.3 % |
10/02/2022 |
The Vanguard Group |
Pennsylvania |
0 |
413855 |
17052432 |
582121 |
17634553 |
6.87 % |
09/02/2022 |
BlackRock, Inc. |
Delaware |
17012577 |
0 |
17649673 |
0 |
17649673 |
6.9 % |
02/02/2022 |
Oracle Investment Management, Inc. |
Delaware |
0 |
11065372 |
0 |
11065372 |
11065372 |
5.82 % |
16/02/2021 |
Oracle Ten Fund, L.P. |
Delaware |
0 |
1790470 |
0 |
1790470 |
1790470 |
0.94 % |
16/02/2021 |
Oracle Partners, L.P. |
Delaware |
0 |
7878701 |
0 |
7878701 |
7878701 |
4.14 % |
16/02/2021 |
Oracle Institutional Partners, L.P. |
Delaware |
0 |
1118201 |
0 |
1118201 |
1118201 |
0.59 % |
16/02/2021 |
Oracle Associates, LLC |
Delaware |
0 |
10787372 |
0 |
10787372 |
10787372 |
5.67 % |
16/02/2021 |
Larry N. Feinberg |
United States |
725000 |
11127372 |
725000 |
11127372 |
11852372 |
6.23 % |
16/02/2021 |
The Feinberg Family Foundation |
Connecticut |
0 |
62000 |
0 |
62000 |
62000 |
0.03 % |
16/02/2021 |
Oracle Investment Management, Inc. Employees’ Retirement Plan |
Delaware |
0 |
278000 |
0 |
278000 |
278000 |
0.15 % |
16/02/2021 |
Cormorant Asset Management, LP |
Delaware |
0 |
7000000 |
0 |
7000000 |
7000000 |
3.7 % |
16/02/2021 |
Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
0 |
6737865 |
0 |
6737865 |
6737865 |
3.5 % |
16/02/2021 |
Cormorant Global Healthcare GP, LLC |
Delaware |
0 |
6737865 |
0 |
6737865 |
6737865 |
3.5 % |
16/02/2021 |
Bihua Chen |
United States |
0 |
7000000 |
0 |
7000000 |
7000000 |
3.7 % |
16/02/2021 |
Cormorant Asset Management, LP |
Delaware |
0 |
7000000 |
0 |
7000000 |
7000000 |
3.7 % |
16/02/2021 |
Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
0 |
6737865 |
0 |
6737865 |
6737865 |
3.5 % |
16/02/2021 |
Cormorant Global Healthcare GP, LLC |
Delaware |
0 |
6737865 |
0 |
6737865 |
6737865 |
3.5 % |
16/02/2021 |
Bihua Chen |
United States |
0 |
7000000 |
0 |
7000000 |
7000000 |
3.7 % |
16/02/2021 |
RTW Investments, LP |
Delaware United States America |
0 |
12864677 |
0 |
12864677 |
12864677 |
6.76 % |
12/02/2021 |
RTW Master Fund, Ltd. |
Cayman Islands |
0 |
8197526 |
0 |
8197526 |
8197526 |
4.31 % |
12/02/2021 |
Roderick Wong |
United States America |
0 |
12864677 |
0 |
12864677 |
12864677 |
6.76 % |
12/02/2021 |
Incyte Corporation |
|
|
|
|
|
14062227 |
7.4 % |
11/02/2021 |
Incyte Corporation |
|
|
|
|
|
14062227 |
7.4 % |
11/02/2021 |
The Vanguard Group |
Pennsylvania |
0 |
364109 |
9055577 |
466611 |
9522188 |
5.01 % |
10/02/2021 |
STATE STREET CORPORATION |
BOSTON, MASSACHUSETTS |
0 |
9700264 |
0 |
10300531 |
10300531 |
5.42 % |
05/02/2021 |
BlackRock, Inc. |
Delaware |
13933470 |
0 |
14517609 |
0 |
14517609 |
7.6 % |
28/01/2021 |
Oracle Institutional Partners, L.P. |
Delaware |
0 |
1242916 |
0 |
1242916 |
1242916 |
0.7 % |
30/07/2020 |
Oracle Ten Fund, L.P. |
Delaware |
0 |
1979190 |
0 |
1979190 |
1979190 |
1.1 % |
30/07/2020 |
Oracle Associates, LLC |
Delaware |
0 |
11956263 |
0 |
11956263 |
11956263 |
6.6 % |
30/07/2020 |
Oracle Investment Management, Inc. |
Delaware |
0 |
12234263 |
0 |
12234263 |
12234263 |
6.7 % |
30/07/2020 |
Oracle Investment Management, Inc. Employees’ Retirement Plan |
Delaware |
0 |
278000 |
0 |
278000 |
278000 |
0.2 % |
30/07/2020 |
The Feinberg Family Foundation |
Connecticut |
0 |
62000 |
0 |
62000 |
62000 |
0.03 % |
30/07/2020 |
Oracle Institutional Partners, L.P. |
Delaware |
0 |
1242916 |
0 |
1242916 |
1242916 |
0.7 % |
30/07/2020 |
Larry N. Feinberg |
United States |
690237 |
12296263 |
690237 |
12296263 |
12986500 |
7.1 % |
30/07/2020 |
Larry N. Feinberg |
United States |
690237 |
12296263 |
690237 |
12296263 |
12986500 |
7.1 % |
30/07/2020 |
The Feinberg Family Foundation |
Connecticut |
0 |
62000 |
0 |
62000 |
62000 |
0.03 % |
30/07/2020 |
Oracle Investment Management, Inc. Employees’ Retirement Plan |
Delaware |
0 |
278000 |
0 |
278000 |
278000 |
0.2 % |
30/07/2020 |
Oracle Investment Management, Inc. |
Delaware |
0 |
12234263 |
0 |
12234263 |
12234263 |
6.7 % |
30/07/2020 |
Oracle Associates, LLC |
Delaware |
0 |
11956263 |
0 |
11956263 |
11956263 |
6.6 % |
30/07/2020 |
Oracle Ten Fund, L.P. |
Delaware |
0 |
1979190 |
0 |
1979190 |
1979190 |
1.1 % |
30/07/2020 |
Oracle Partners, L.P. |
Delaware |
0 |
8734157 |
0 |
8734157 |
8734157 |
4.8 % |
30/07/2020 |
Oracle Partners, L.P. |
Delaware |
0 |
8734157 |
0 |
8734157 |
8734157 |
4.8 % |
30/07/2020 |
Cormorant Global Healthcare GP, LLC |
Delaware |
0 |
10921550 |
0 |
10921550 |
10921550 |
6.76 % |
20/03/2020 |
Bihua Chen |
United States |
0 |
11500000 |
0 |
11500000 |
11500000 |
7.12 % |
20/03/2020 |
Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
0 |
10921550 |
0 |
10921550 |
10921550 |
6.76 % |
20/03/2020 |
Cormorant Asset Management, LP |
Delaware |
0 |
11500000 |
0 |
11500000 |
11500000 |
7.12 % |
20/03/2020 |
Bihua Chen |
United States |
0 |
11500000 |
0 |
11500000 |
11500000 |
7.12 % |
20/03/2020 |
Cormorant Global Healthcare Master Fund, LP |
Cayman Islands |
0 |
10921550 |
0 |
10921550 |
10921550 |
6.76 % |
20/03/2020 |
Cormorant Global Healthcare GP, LLC |
Delaware |
0 |
10921550 |
0 |
10921550 |
10921550 |
6.76 % |
20/03/2020 |
Cormorant Asset Management, LP |
Delaware |
0 |
11500000 |
0 |
11500000 |
11500000 |
7.12 % |
20/03/2020 |
RTW Master Fund, Ltd. |
Cayman Islands |
0 |
7200329 |
0 |
7200329 |
7200329 |
5.24 % |
14/02/2020 |
Roderick Wong |
United States of America |
0 |
13725251 |
0 |
13725251 |
13725251 |
9.99 % |
14/02/2020 |
RTW Investments, LP |
Delaware, United States of America |
0 |
13725251 |
0 |
13725251 |
13725251 |
9.99 % |
14/02/2020 |
BlackRock, Inc. |
Delaware |
9642495 |
0 |
10340176 |
0 |
10340176 |
7.5 % |
05/02/2020 |
Point72 Asset Management, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2019 |
Steven A. Cohen |
United States |
0 |
1113 |
0 |
1113 |
1113 |
0.1 % |
14/02/2019 |
Point72 Hong Kong Limited |
Hong Kong |
0 |
1113 |
0 |
1113 |
1113 |
0.1 % |
14/02/2019 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2019 |
RTW Investments, LP |
Delaware, United States of America |
0 |
14984569 |
0 |
14984569 |
14984569 |
9.99 % |
14/02/2019 |
Roderick Wong |
United States of America |
0 |
14984569 |
0 |
14984569 |
14984569 |
9.99 % |
14/02/2019 |
RTW Master Fund, Ltd. |
Cayman Islands |
0 |
8813170 |
0 |
8813170 |
8813170 |
5.88 % |
14/02/2019 |
BlackRock, Inc. |
Delaware |
6548502 |
0 |
6846902 |
0 |
6846902 |
5.7 % |
07/02/2019 |
Gilead Sciences, Inc. |
Delaware |
11111111 |
0 |
11111111 |
0 |
11111111 |
9.3 % |
28/01/2019 |
Point72 Asset Management, L.P. |
Delaware |
0 |
6144144 |
0 |
6144144 |
6144144 |
6 % |
05/03/2018 |
Point72 Asset Management, L.P. |
Delaware |
0 |
6144144 |
0 |
6144144 |
6144144 |
6 % |
05/03/2018 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
6144144 |
0 |
6144144 |
6144144 |
6 % |
05/03/2018 |
Steven A. Cohen |
United States |
0 |
6144144 |
0 |
6144144 |
6144144 |
6 % |
05/03/2018 |
Steven A. Cohen |
United States |
0 |
6144144 |
0 |
6144144 |
6144144 |
6 % |
05/03/2018 |
Point72 Capital Advisors, Inc. |
Delaware |
0 |
6144144 |
0 |
6144144 |
6144144 |
6 % |
05/03/2018 |
QVT Financial GP LLC |
Delaware |
0 |
3201263 |
0 |
3201263 |
3201263 |
3.2 % |
14/02/2018 |
QVT Financial LP |
Delaware |
0 |
3201263 |
0 |
3201263 |
3201263 |
3.2 % |
14/02/2018 |
QVT Associates GP LLC |
Delaware |
0 |
3201263 |
0 |
3201263 |
3201263 |
3.2 % |
14/02/2018 |
QVT Financial GP LLC |
Delaware |
0 |
3201263 |
0 |
3201263 |
3201263 |
3.2 % |
14/02/2018 |
QVT Financial LP |
Delaware |
0 |
3201263 |
0 |
3201263 |
3201263 |
3.2 % |
14/02/2018 |
QVT Associates GP LLC |
Delaware |
0 |
3201263 |
0 |
3201263 |
3201263 |
3.2 % |
14/02/2018 |
Roderick Wong |
United States of America |
0 |
5009949 |
0 |
5009949 |
5009949 |
5 % |
12/02/2018 |
RTW Investments, LP |
Delaware, United States of America |
0 |
5009949 |
0 |
5009949 |
5009949 |
5 % |
12/02/2018 |
BlackRock, Inc. |
Delaware |
4737088 |
0 |
4883221 |
0 |
4883221 |
4.9 % |
29/01/2018 |
Incyte Corporation |
Delaware |
17763968 |
0 |
17763968 |
0 |
17763968 |
18.1 % |
14/02/2017 |
FMR LLC |
Delaware |
0 |
0 |
3620778 |
0 |
3620778 |
4.062 % |
14/02/2017 |
Abigail P. Johnson |
United States of America |
0 |
0 |
3620778 |
0 |
3620778 |
4.062 % |
14/02/2017 |
FMR LLC |
Delaware |
0 |
0 |
3620778 |
0 |
3620778 |
4.062 % |
14/02/2017 |
Abigail P. Johnson |
United States of America |
0 |
0 |
3620778 |
0 |
3620778 |
4.062 % |
14/02/2017 |
Behzad Aghazadeh |
United States |
4750430 |
0 |
4750430 |
0 |
4750430 |
5.41 % |
09/02/2017 |
venBio Select Advisor LLC |
Delaware |
4750430 |
0 |
4750430 |
0 |
4750430 |
5.41 % |
09/02/2017 |
QVT Financial GP LLC |
Delaware |
0 |
4455874 |
0 |
4455874 |
4455874 |
5.08 % |
03/02/2017 |
QVT Associates GP LLC |
Delaware |
0 |
4455874 |
0 |
4455874 |
4455874 |
5.08 % |
03/02/2017 |
QVT Associates GP LLC |
Delaware |
0 |
4455874 |
0 |
4455874 |
4455874 |
5.08 % |
03/02/2017 |
QVT Financial GP LLC |
Delaware |
0 |
4455874 |
0 |
4455874 |
4455874 |
5.08 % |
03/02/2017 |
QVT Financial LP |
Delaware |
0 |
4455874 |
0 |
4455874 |
4455874 |
5.08 % |
03/02/2017 |
QVT Financial LP |
Delaware |
0 |
4455874 |
0 |
4455874 |
4455874 |
5.08 % |
03/02/2017 |
BlackRock, Inc. |
Delaware |
4641583 |
0 |
4793491 |
0 |
4793491 |
5.5 % |
30/01/2017 |
Abigail P. Johnson |
United States of America |
0 |
0 |
4789278 |
0 |
4789278 |
5.527 % |
12/02/2016 |
Abigail P. Johnson |
United States of America |
0 |
0 |
4789278 |
0 |
4789278 |
5.527 % |
12/02/2016 |
FMR LLC |
Delaware |
0 |
0 |
4789278 |
0 |
4789278 |
5.527 % |
12/02/2016 |
FMR LLC |
Delaware |
0 |
0 |
4789278 |
0 |
4789278 |
5.527 % |
12/02/2016 |
QVT Fund V LP . |
Cayman Islands |
0 |
1956715 |
0 |
1956715 |
1956715 |
2.26 % |
10/02/2016 |
QVT Associates GP LLC . |
Delaware |
0 |
2680321 |
0 |
2680321 |
2680321 |
3.1 % |
10/02/2016 |
QVT Financial LP . |
Delaware |
0 |
2680321 |
0 |
2680321 |
2680321 |
3.1 % |
10/02/2016 |
QVT Financial LP . |
Delaware |
0 |
2680321 |
0 |
2680321 |
2680321 |
3.1 % |
10/02/2016 |
QVT Financial GP LLC . |
Delaware |
0 |
2680321 |
0 |
2680321 |
2680321 |
3.1 % |
10/02/2016 |
QVT Associates GP LLC . |
Delaware |
0 |
2680321 |
0 |
2680321 |
2680321 |
3.1 % |
10/02/2016 |
QVT Fund V LP . |
Cayman Islands |
0 |
1956715 |
0 |
1956715 |
1956715 |
2.26 % |
10/02/2016 |
QVT Financial GP LLC . |
Delaware |
0 |
2680321 |
0 |
2680321 |
2680321 |
3.1 % |
10/02/2016 |
BlackRock, Inc. |
Delaware |
4013901 |
0 |
4103628 |
0 |
4103628 |
4.99 % |
10/06/2015 |
Abigail P. Johnson |
United States of America |
0 |
0 |
2159514 |
0 |
2159514 |
2.967 % |
10/04/2015 |
FMR LLC |
Delaware |
0 |
0 |
2159514 |
0 |
2159514 |
2.967 % |
10/04/2015 |
FMR LLC |
Delaware |
0 |
0 |
2159514 |
0 |
2159514 |
2.967 % |
10/04/2015 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
2159514 |
0 |
2159514 |
2.967 % |
10/04/2015 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
2159514 |
0 |
2159514 |
2.967 % |
10/04/2015 |
Abigail P. Johnson |
United States of America |
0 |
0 |
2159514 |
0 |
2159514 |
2.967 % |
10/04/2015 |
Incyte Corporation |
Delaware |
7763968 |
0 |
7763968 |
0 |
7763968 |
11 % |
20/02/2015 |
Incyte Corporation |
Delaware |
7763968 |
0 |
7763968 |
0 |
7763968 |
11 % |
20/02/2015 |
INGALLS & SNYDER VALUE PARTNERS, L.P. 133694561 |
NEW YORK STATE |
|
0 |
0 |
0 |
0 |
0 % |
06/02/2015 |
INGALLS & SNYDER, LLC |
New York |
0 |
0 |
0 |
0 |
0 |
0 % |
06/02/2015 |
INGALLS & SNYDER, LLC |
New York |
0 |
0 |
0 |
0 |
0 |
0 % |
06/02/2015 |
BlackRock, Inc. |
Delaware |
4156483 |
0 |
4253469 |
0 |
4253469 |
6.8 % |
02/02/2015 |
QVT Associates GP LLC |
Delaware |
0 |
6915630 |
0 |
6915630 |
6915630 |
9.82 % |
13/01/2015 |
QVT Associates GP LLC |
Delaware |
0 |
6915630 |
0 |
6915630 |
6915630 |
9.82 % |
13/01/2015 |
QVT Fund V LP |
Cayman Islands |
0 |
5385888 |
0 |
5385888 |
5385888 |
7.65 % |
13/01/2015 |
QVT Financial LP |
Delaware |
0 |
6915630 |
0 |
6915630 |
6915630 |
9.82 % |
13/01/2015 |
QVT Financial LP |
Delaware |
0 |
6915630 |
0 |
6915630 |
6915630 |
9.82 % |
13/01/2015 |
QVT Financial GP LLC |
Delaware |
0 |
6915630 |
0 |
6915630 |
6915630 |
9.82 % |
13/01/2015 |
QVT Fund V LP |
Cayman Islands |
0 |
5385888 |
0 |
5385888 |
5385888 |
7.65 % |
13/01/2015 |
QVT Financial GP LLC |
Delaware |
0 |
6915630 |
0 |
6915630 |
6915630 |
9.82 % |
13/01/2015 |
QVT Financial GP LLC |
Delaware |
0 |
9259260 |
0 |
9259260 |
9259260 |
16.11 % |
14/02/2014 |
QVT Financial LP . |
Delaware |
0 |
9259260 |
0 |
9259260 |
9259260 |
16.11 % |
14/02/2014 |
QVT Associates GP LLC |
Delaware |
0 |
9259260 |
0 |
9259260 |
9259260 |
16.11 % |
14/02/2014 |
QVT Fund V LP . |
Cayman Islands |
0 |
7211104 |
0 |
7211104 |
7211104 |
12.55 % |
14/02/2014 |
QVT Associates GP LLC . |
Delaware |
0 |
9259260 |
0 |
9259260 |
9259260 |
16.11 % |
14/02/2014 |
QVT Fund V LP |
Cayman Islands |
0 |
7211104 |
0 |
7211104 |
7211104 |
12.55 % |
14/02/2014 |
QVT Financial GP LLC . |
Delaware |
0 |
9259260 |
0 |
9259260 |
9259260 |
16.11 % |
14/02/2014 |
QVT Financial LP |
Delaware |
0 |
9259260 |
0 |
9259260 |
9259260 |
16.11 % |
14/02/2014 |
Oracle Associates, LLC |
Delaware |
0 |
1003414 |
0 |
1003414 |
1003414 |
2.8 % |
13/02/2014 |
Oracle Partners, L.P. |
Delaware |
0 |
1003414 |
0 |
1003414 |
1003414 |
2.8 % |
13/02/2014 |
Larry N. Feinberg |
United States |
500000 |
1003414 |
500000 |
1003414 |
1503414 |
4.2 % |
13/02/2014 |
INGALLS & SNYDER VALUE PARTNERS, L.P. 133694561 |
NEW YORK STATE |
|
0 |
0 |
2000000 |
2000000 |
5.6 % |
07/02/2014 |
INGALLS & SNYDER, LLC |
New York |
0 |
0 |
0 |
2000000 |
2000000 |
5.6 % |
07/02/2014 |
INGALLS & SNYDER, LLC |
New York |
0 |
0 |
0 |
2000000 |
2000000 |
5.6 % |
07/02/2014 |
Sabby Management, LLC |
Delaware USA |
0 |
680100 |
0 |
680100 |
680100 |
1.92 % |
28/01/2014 |
Sabby Volatility Warrant Master Fund, Ltd. |
Cayman Islands |
0 |
130000 |
0 |
130000 |
130000 |
0.37 % |
28/01/2014 |
Sabby Healthcare Volatility Master Fund, Ltd. |
Cayman Islands |
0 |
550100 |
0 |
550100 |
550100 |
1.55 % |
28/01/2014 |
Sabby Volatility Warrant Master Fund, Ltd. |
Cayman Islands |
0 |
130000 |
0 |
130000 |
130000 |
0.37 % |
28/01/2014 |
Sabby Management, LLC |
Delaware USA |
0 |
680100 |
0 |
680100 |
680100 |
1.92 % |
28/01/2014 |
Hal Mintz |
USA |
0 |
680100 |
0 |
680100 |
680100 |
1.92 % |
28/01/2014 |
Hal Mintz |
USA |
0 |
680100 |
0 |
680100 |
680100 |
1.92 % |
28/01/2014 |
Sabby Healthcare Volatility Master Fund, Ltd. |
Cayman Islands |
0 |
550100 |
0 |
550100 |
550100 |
1.55 % |
28/01/2014 |
Hal Mintz |
USA |
0 |
2166666 |
0 |
2166666 |
2166666 |
6.36 % |
23/09/2013 |
Sabby Management, LLC |
Delaware USA |
0 |
2166666 |
0 |
2166666 |
2166666 |
6.36 % |
23/09/2013 |
Hal Mintz |
USA |
0 |
2166666 |
0 |
2166666 |
2166666 |
6.36 % |
23/09/2013 |
Sabby Volatility Warrant Master Fund, Ltd. |
Cayman Islands |
0 |
433333 |
0 |
433333 |
433333 |
1.27 % |
23/09/2013 |
Sabby Volatility Warrant Master Fund, Ltd. |
Cayman Islands |
0 |
433333 |
0 |
433333 |
433333 |
1.27 % |
23/09/2013 |
Sabby Management, LLC |
Delaware USA |
0 |
2166666 |
0 |
2166666 |
2166666 |
6.36 % |
23/09/2013 |
Sabby Healthcare Volatility Master Fund, Ltd. |
Cayman Islands |
0 |
1733333 |
0 |
1733333 |
1733333 |
5.09 % |
23/09/2013 |
Sabby Healthcare Volatility Master Fund, Ltd. |
Cayman Islands |
0 |
1733333 |
0 |
1733333 |
1733333 |
5.09 % |
23/09/2013 |
BlackRock, Inc. |
Delaware |
789996 |
0 |
789996 |
0 |
789996 |
2.79 % |
10/07/2013 |
INGALLS & SNYDER VALUE PARTNERS, L.P. 133694561 |
NEW YORK STATE |
|
0 |
0 |
2000000 |
2000000 |
7.2 % |
18/04/2013 |
INGALLS & SNYDER, LLC |
New York |
0 |
0 |
0 |
2116034 |
2116034 |
7.6 % |
18/04/2013 |
Larry N. Feinberg |
United States |
385806 |
966399 |
385806 |
966399 |
1352205 |
5.44 % |
12/02/2013 |
Oracle Associates, LLC |
Delaware |
0 |
966399 |
0 |
966399 |
966399 |
3.89 % |
12/02/2013 |
Oracle Partners, LP |
Delaware |
0 |
966399 |
0 |
966399 |
966399 |
3.89 % |
12/02/2013 |
BlackRock, Inc. |
Delaware |
1658127 |
0 |
1658127 |
0 |
1658127 |
6.74 % |
30/01/2013 |
Invus Public Equities, L.P. |
Bermuda |
0 |
4546079 |
0 |
4546079 |
4546079 |
4.9 % |
13/02/2012 |
Invus Public Equities Advisors, L.L.C. |
Delaware |
0 |
4546079 |
0 |
4546079 |
4546079 |
4.9 % |
13/02/2012 |
Ulys, L.L.C. |
Delaware |
0 |
4546079 |
0 |
4546079 |
4546079 |
4.9 % |
13/02/2012 |
Raymond Debbane |
Panama |
0 |
4546079 |
0 |
4546079 |
4546079 |
4.9 % |
13/02/2012 |
INGALLS & SNYDER VALUE PARTNERS, L.P. 133694561 |
NEW YORK STATE |
|
0 |
0 |
1070019 |
1070019 |
4.98 % |
07/02/2012 |
INGALLS & SNYDER VALUE PARTNERS, L.P. 133694561 |
NEW YORK STATE |
|
0 |
0 |
6746601 |
6746601 |
5.99 % |
24/02/2011 |
INGALLS & SNYDER VALUE PARTNERS, L.P. |
NEW YORK STATE |
11664001 |
0 |
0 |
11664001 |
11664001 |
9.99 % |
11/02/2011 |
INGALLS & SNYDER VALUE PARTNERS, L.P. 133694561 |
NEW YORK STATE |
|
0 |
0 |
10385112 |
10385112 |
9.4 % |
29/11/2010 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
2446500 |
0 |
2446500 |
2.542 % |
10/06/2010 |
FMR LLC |
Delaware |
0 |
0 |
2446500 |
0 |
2446500 |
2.542 % |
10/06/2010 |
FMR LLC |
Delaware |
0 |
0 |
7275800 |
0 |
7275800 |
7.6 % |
16/02/2010 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
7275800 |
0 |
7275800 |
7.6 % |
16/02/2010 |
Alphonse Fletcher, Jr. |
United States |
0 |
0 |
0 |
0 |
100000 |
0.1 % |
16/02/2010 |
Fletcher International, Ltd. |
Bermuda |
0 |
0 |
0 |
0 |
100000 |
0.1 % |
16/02/2010 |
Fletcher Asset Management, Inc. |
Delaware |
100000 |
0 |
100000 |
0 |
100000 |
0.1 % |
16/02/2010 |
INGALLS & SNYDER VALUE PARTNERS, L.P. |
NEW YORK STATE |
8348967 |
0 |
0 |
8348967 |
8348967 |
8.5 % |
11/02/2010 |
BAM Management, LLC |
Delaware, U.S.A. |
0 |
4676400 |
0 |
4676400 |
4676400 |
4.99 % |
13/01/2010 |
BAM Capital, LLC |
Delaware, U.S.A. |
0 |
0 |
0 |
0 |
0 |
0 % |
13/01/2010 |
Ross Berman |
United States of America |
0 |
4676400 |
0 |
4676400 |
4676400 |
4.99 % |
13/01/2010 |
BAM Opportunity Fund SPV, LLC |
Delaware, U.S.A. |
0 |
4676400 |
0 |
4676400 |
4676400 |
4.99 % |
13/01/2010 |
Hal Mintz |
United States of America |
0 |
4676400 |
0 |
4676400 |
4676400 |
4.99 % |
13/01/2010 |
BAM Opportunity Fund, L.P. |
Delaware, U.S.A. |
0 |
0 |
0 |
0 |
0 |
0 % |
13/01/2010 |