| OrbiMed Capital GP IX LLC |
Delaware |
0 |
644667 |
0 |
0 |
644667 |
6.7 % |
14/11/2024 |
| OrbiMed Advisors LLC |
Delaware |
0 |
967000 |
0 |
0 |
967000 |
9.9 % |
14/11/2024 |
| OrbiMed Advisors LLC |
Delaware |
0 |
967000 |
0 |
0 |
967000 |
9.9 % |
14/11/2024 |
| OrbiMed Capital GP IX LLC |
Delaware |
0 |
644667 |
0 |
0 |
644667 |
6.7 % |
14/11/2024 |
| Ikarian Capital, LLC |
Delaware |
0 |
970359 |
0 |
970359 |
970359 |
10.02 % |
07/10/2024 |
| Ikarian Capital, LLC |
Delaware |
0 |
970359 |
0 |
970359 |
970359 |
10.02 % |
07/10/2024 |
| Neil Shahrestani |
Delaware |
0 |
970359 |
0 |
0 |
970359 |
10.02 % |
07/10/2024 |
| Neil Shahrestani |
Delaware |
0 |
970359 |
0 |
0 |
970359 |
10.02 % |
07/10/2024 |
| BVF I GP LLC |
Delaware |
0 |
0 |
0 |
512349 |
512349 |
5.3 % |
23/08/2024 |
| BVF Inc. |
Delaware |
0 |
0 |
0 |
967299 |
967299 |
9.99 % |
23/08/2024 |
| Biotechnology Value Fund, L.P. |
Delaware |
0 |
0 |
0 |
512349 |
512349 |
5.3 % |
23/08/2024 |
| BVF I GP LLC |
Delaware |
0 |
0 |
0 |
512349 |
512349 |
5.3 % |
23/08/2024 |
| Biotechnology Value Fund II, L.P. |
Delaware |
0 |
0 |
0 |
403121 |
403121 |
4.2 % |
23/08/2024 |
| BVF II GP LLC |
Delaware |
0 |
0 |
0 |
403121 |
403121 |
4.2 % |
23/08/2024 |
| Biotechnology Value Fund, L.P. |
Delaware |
0 |
0 |
0 |
512349 |
512349 |
5.3 % |
23/08/2024 |
| BVF Partners L.P. |
Delaware |
0 |
0 |
0 |
967299 |
967299 |
9.99 % |
23/08/2024 |
| BVF Partners L.P. |
Delaware |
0 |
0 |
0 |
967299 |
967299 |
9.99 % |
23/08/2024 |
| BVF GP Holdings LLC |
Delaware |
0 |
0 |
0 |
915470 |
915470 |
9.5 % |
23/08/2024 |
| Mark N. Lampert |
Delaware |
0 |
0 |
0 |
967299 |
967299 |
9.99 % |
23/08/2024 |
| BVF Inc. |
Delaware |
0 |
0 |
0 |
967299 |
967299 |
9.99 % |
23/08/2024 |
| BVF GP Holdings LLC |
Delaware |
0 |
0 |
0 |
915470 |
915470 |
9.5 % |
23/08/2024 |
| BVF Partners OS Ltd. |
Delaware |
0 |
0 |
0 |
37791 |
37791 |
1 % |
23/08/2024 |
| Biotechnology Value Trading Fund OS LP |
Delaware |
0 |
0 |
0 |
37791 |
37791 |
1 % |
23/08/2024 |
| BVF II GP LLC |
Delaware |
0 |
0 |
0 |
403121 |
403121 |
4.2 % |
23/08/2024 |
| Biotechnology Value Fund II, L.P. |
Delaware |
0 |
0 |
0 |
403121 |
403121 |
4.2 % |
23/08/2024 |
| Biotechnology Value Trading Fund OS LP |
Delaware |
0 |
0 |
0 |
37791 |
37791 |
1 % |
23/08/2024 |
| BVF Partners OS Ltd. |
Delaware |
0 |
0 |
0 |
37791 |
37791 |
1 % |
23/08/2024 |
| Mark N. Lampert |
Delaware |
0 |
0 |
0 |
967299 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| s |
Delaware |
0 |
967299 |
0 |
0 |
967299 |
9.99 % |
23/08/2024 |
| J. Crutcher |
USA |
110851 |
0 |
110851 |
0 |
110851 |
9.9 % |
23/08/2024 |
| J. Crutcher |
USA |
110851 |
0 |
110851 |
0 |
110851 |
9.9 % |
23/08/2024 |
| Christopher Staral |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Allostery Master Fund LP |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Allostery Investments LP |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| David Modest |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Allostery Master Fund LP |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Allostery Investments LP |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Allostery Investments GP LLC |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Christopher Staral |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Allostery Investments GP LLC |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| David Modest |
Cayman Islands |
0 |
78255 |
0 |
78255 |
78255 |
7.6 % |
13/05/2024 |
| Timothy Opler |
Delaware |
0 |
58346 |
0 |
58346 |
58346 |
5.6 % |
23/04/2024 |
| Emerald Bioventures, LLC |
Delaware |
0 |
58346 |
0 |
58346 |
58346 |
5.6 % |
23/04/2024 |
| Emerald Bioventures, LLC |
Delaware |
0 |
58346 |
0 |
58346 |
58346 |
5.6 % |
23/04/2024 |
| Timothy Opler |
Delaware |
0 |
58346 |
0 |
58346 |
58346 |
5.6 % |
23/04/2024 |
| David Kroin |
Delaware |
0 |
114775 |
0 |
0 |
114775 |
9.99 % |
05/04/2024 |
| Deep Track Biotechnology Master Fund, Ltd. |
Delaware |
0 |
114775 |
0 |
0 |
114775 |
9.99 % |
05/04/2024 |
| Deep Track Biotechnology Master Fund, Ltd. |
Delaware |
0 |
114775 |
0 |
0 |
114775 |
9.99 % |
05/04/2024 |
| Deep Track Capital, LP |
Delaware |
0 |
114775 |
0 |
0 |
114775 |
9.99 % |
05/04/2024 |
| David Kroin |
Delaware |
0 |
114775 |
0 |
0 |
114775 |
9.99 % |
05/04/2024 |
| Deep Track Capital, LP |
Delaware |
0 |
114775 |
0 |
0 |
114775 |
9.99 % |
05/04/2024 |
| VHCP Management EG, LLC |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Koh, Bong |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Shah, Nimish |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Venrock Healthcare Capital Partners EG, L.P. |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| VHCP Management III, LLC |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Koh, Bong |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| VHCP Co-Investment Holdings III, LLC |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Venrock Healthcare Capital Partners III, L.P. |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| VHCP Management EG, LLC |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Shah, Nimish |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| VHCP Co-Investment Holdings III, LLC |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| VHCP Management III, LLC |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Venrock Healthcare Capital Partners EG, L.P. |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Venrock Healthcare Capital Partners III, L.P. |
Delaware |
0 |
1352285 |
0 |
0 |
1352285 |
9.99 % |
17/02/2023 |
| Mr. Ortav Yehudai |
Delaware |
0 |
974639 |
0 |
0 |
974639 |
7.12 % |
13/02/2023 |
| Great Point Partners, LLC |
Delaware |
0 |
974639 |
0 |
0 |
974639 |
7.12 % |
13/02/2023 |
| Dr. Jeffrey R. Jay, M.D. |
Delaware |
0 |
974639 |
0 |
0 |
974639 |
7.12 % |
13/02/2023 |
| Mr. Ortav Yehudai |
USA |
0 |
974639 |
0 |
0 |
974639 |
7.12 % |
13/02/2023 |
| Great Point Partners, LLC |
Delaware |
0 |
974639 |
0 |
0 |
974639 |
7.12 % |
13/02/2023 |
| Dr. Jeffrey R. Jay, M.D. |
USA |
0 |
974639 |
0 |
0 |
974639 |
7.12 % |
13/02/2023 |
| Caissa Capital Management Ltd. |
British Virgin Islands |
798258 |
0 |
798258 |
0 |
798258 |
8.49 % |
08/08/2022 |
| Cambyz Golestaneh |
British Virgin Islands |
980558 |
0 |
980558 |
0 |
980558 |
10.43 % |
08/08/2022 |
| Caissa Capital Management Ltd. |
British Virgin Islands |
4100000 |
0 |
4100000 |
0 |
4100000 |
3.63 % |
17/05/2022 |
| Cambyz Golestaneh |
British Virgin Islands |
6100000 |
0 |
6100000 |
0 |
6100000 |
5.41 % |
17/05/2022 |
| Point72 Asset Management, L.P. |
|
0 |
6008850 |
0 |
6008850 |
6008850 |
4 % |
14/02/2022 |
| Point72 Capital Advisors, Inc. |
|
0 |
6008850 |
0 |
6008850 |
6008850 |
4 % |
14/02/2022 |
| Point72 Hong Kong Limited |
|
0 |
3826 |
0 |
3826 |
3826 |
4 % |
14/02/2022 |
| Steven A. Cohen |
|
0 |
6012676 |
0 |
6012676 |
6012676 |
4 % |
14/02/2022 |
| Daniel Mack |
|
0 |
8513917 |
0 |
0 |
8513917 |
7.5 % |
14/02/2022 |
| Nantahala Capital Management, LLC |
MA |
0 |
8513917 |
0 |
0 |
8513917 |
7.5 % |
14/02/2022 |
| Nantahala Capital Management, LLC |
|
0 |
8513917 |
0 |
0 |
8513917 |
7.5 % |
14/02/2022 |
| Daniel Mack |
USA |
0 |
8513917 |
0 |
0 |
8513917 |
7.5 % |
14/02/2022 |
| Wilmot B. Harkey |
USA |
0 |
8513917 |
0 |
0 |
8513917 |
7.5 % |
14/02/2022 |
| Wilmot B. Harkey |
|
0 |
8513917 |
0 |
0 |
8513917 |
7.5 % |
14/02/2022 |
| Steven Boyd |
|
412442 |
50400000 |
412442 |
50400000 |
50812442 |
43.7 % |
19/01/2022 |
| Armistice Capital, LLC |
|
0 |
50400000 |
0 |
50400000 |
50400000 |
43.3 % |
19/01/2022 |
| Armistice Capital, LLC |
|
0 |
49000000 |
0 |
49000000 |
49000000 |
42.1 % |
16/12/2021 |
| Steven Boyd |
|
412442 |
49000000 |
412442 |
49000000 |
49412442 |
42.5 % |
16/12/2021 |
| Steven A. Cohen |
Delaware |
0 |
6009696 |
0 |
6009696 |
6009696 |
4 % |
21/09/2021 |
| Point72 Asset Management, L.P. |
Delaware |
0 |
6008850 |
0 |
6008850 |
6008850 |
4 % |
21/09/2021 |
| Point72 Capital Advisors, Inc. |
Delaware |
0 |
6008850 |
0 |
6008850 |
6008850 |
4 % |
21/09/2021 |
| Point72 Hong Kong Limited |
Delaware |
0 |
846 |
0 |
846 |
846 |
4 % |
21/09/2021 |
| Point72 Asset Management, L.P. |
Delaware |
0 |
6008850 |
0 |
6008850 |
6008850 |
4 % |
21/09/2021 |
| Point72 Capital Advisors, Inc. |
Delaware |
0 |
6008850 |
0 |
6008850 |
6008850 |
4 % |
21/09/2021 |
| Point72 Hong Kong Limited |
Delaware |
0 |
846 |
0 |
846 |
846 |
4 % |
21/09/2021 |
| Steven A. Cohen |
Delaware |
0 |
6009696 |
0 |
6009696 |
6009696 |
4 % |
21/09/2021 |
| Steven Boyd |
|
412442 |
49000000 |
412442 |
49000000 |
412442 |
43.9 % |
17/09/2021 |
| Armistice Capital, LLC |
|
0 |
49000000 |
0 |
49000000 |
49000000 |
43.6 % |
17/09/2021 |
| Wilmot B. Harkey |
USA |
0 |
6233316 |
0 |
0 |
6233316 |
8.3 % |
16/02/2021 |
| Nantahala Capital Management, LLC |
MA |
0 |
6233316 |
0 |
0 |
6233316 |
8.3 % |
16/02/2021 |
| Nantahala Capital Management, LLC |
MA |
0 |
6233316 |
0 |
0 |
6233316 |
8.3 % |
16/02/2021 |
| Daniel Mack |
USA |
0 |
6233316 |
0 |
0 |
6233316 |
8.3 % |
16/02/2021 |
| Wilmot B. Harkey |
MA |
0 |
6233316 |
0 |
0 |
6233316 |
8.3 % |
16/02/2021 |
| Daniel Mack |
MA |
0 |
6233316 |
0 |
0 |
6233316 |
8.3 % |
16/02/2021 |
| ARK ASSET MANGEMENT CO., INC. |
Massachusetts |
0 |
2185536 |
0 |
2185536 |
0 |
0 % |
03/10/2018 |
| 1 |
Massachusetts |
0 |
2185536 |
0 |
2185536 |
9 |
11 % |
03/10/2018 |
| 1 |
Massachusetts |
0 |
2185536 |
0 |
2185536 |
9 |
11 % |
03/10/2018 |
| Opaleye
Management Inc. |
Massachusetts |
0 |
2185536 |
0 |
2185536 |
9 |
11 % |
03/10/2018 |
| Sharyar Baradaran |
U.S.A. |
809314 |
0 |
809314 |
0 |
809314 |
2.59 % |
12/02/2018 |
| Seth L. Harrison |
United States citizen |
0 |
595436 |
0 |
0 |
595436 |
6.9 % |
12/02/2016 |
| ATP III GP, Ltd. |
Cayman Islands exempted limited partnership |
0 |
595436 |
0 |
0 |
595436 |
6.9 % |
12/02/2016 |
| Apple Tree Partners IV, L.P. |
Cayman Islands exempted limited partnership |
0 |
595436 |
0 |
0 |
595436 |
6.9 % |
12/02/2016 |
| NEA Partners 14, L.P. |
Cayman Islands exempted limited partnership |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Krishna S. Kolluri |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Scott D. Sandell |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Forest Baskett |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Peter J. Barris |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| New Enterprise Associates 14, L.P. |
Cayman Islands exempted limited partnership |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Krishna S. Kolluri |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Forest Baskett |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Patrick J. Kerins |
citizen |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Harry R. Weller |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Ravi Viswanathan |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Peter W. Sonsini |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Scott D. Sandell |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| David M. Mott |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Patrick J. Kerins |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Anthony A. Florence, Jr. |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Peter J. Barris |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| M. James Barrett |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| NEA 14 GP, LTD |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| New Enterprise Associates 14, L.P. |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| NEA Partners 14, L.P. |
Cayman Islands exempted |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| M. James Barrett |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Anthony A. Florence, Jr. |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Peter W. Sonsini |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| David M. Mott |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Ravi Viswanathan |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| Harry R. Weller |
United States |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |
| NEA 14 GP, LTD |
Cayman Islands exempted company |
0 |
594245 |
0 |
0 |
594245 |
6.9 % |
01/02/2016 |