CALA

Calithera Biosciences, Inc. CALA

Individual Beneficiary

Name of reporting person Citizenship or organization Sole voting power Shared voting power Sole dispositive power Shared dispositive power Amount beneficially owned Percent of class Accepted date
Incyte Corporation 0 0 % 08/02/2023
Incyte Corporation 0 0 % 08/02/2023
PRIMECAP Management Company 177 E. Colorado Blvd., 11th Floor, Pasadena, CA 91105 406280 0 406280 0 406280 8.35 % 08/12/2022
Kenneth Griffin U.S. Citizen 0 5035077 0 6 6 5.4 % 11/04/2022
Citadel Advisors LLC Delaware 0 4993833 0 6 6 5.31 % 11/04/2022
Citadel Advisors Holdings LP Delaware 0 4993833 0 6 6 5.3 % 11/04/2022
Citadel GP LLC Delaware 0 4993833 0 6 6 5.3 % 11/04/2022
Citadel Securities LLC Delaware 0 40814 0 6 6 0 % 11/04/2022
Citadel Securities Group LP Delaware 0 41244 0 6 6 0 % 11/04/2022
Citadel Securities GP LLC Delaware 0 41244 0 6 6 0 % 11/04/2022
Citadel Advisors LLC Delaware 0 4993833 0 6 6 5.31 % 11/04/2022
Citadel Advisors Holdings LP Delaware 0 4993833 0 6 6 5.3 % 11/04/2022
Citadel GP LLC Delaware 0 4993833 0 6 6 5.3 % 11/04/2022
Citadel Securities LLC Delaware 0 40814 0 6 6 0 % 11/04/2022
Citadel Securities Group LP Delaware 0 41244 0 6 6 0 % 11/04/2022
Citadel Securities GP LLC Delaware 0 41244 0 6 6 0 % 11/04/2022
Kenneth Griffin U.S. Citizen 0 5035077 0 6 6 5.4 % 11/04/2022
The Vanguard Group Pennsylvania 0 0 2840559 21037 2861596 3.82 % 09/02/2022
Rhodora J. Donahue 1418 1418 1418 0 % 10/12/2021
J. Christopher Donahue 1418 1418 1418 0 % 10/12/2021
Thomas R. Donahue 1418 1418 1418 0 % 10/12/2021
(entities only Federated Hermes, Inc. 1418 1418 1418 0 % 10/12/2021
Voting Shares Irrevocable Trust 1418 1418 1418 0 % 10/12/2021
Citadel GP LLC Delaware 0 3493833 0 3493833 3493833 4.7 % 22/11/2021
Citadel Advisors LLC Delaware 0 3493833 0 3493833 3493833 4.7 % 22/11/2021
Citadel Securities Group LP Delaware 0 190310 0 190310 190310 0.3 % 22/11/2021
Citadel Securities GP LLC Delaware 0 190310 0 190310 190310 0.3 % 22/11/2021
Kenneth Griffin U.S. Citizen 0 3684143 0 3684143 3684143 4.9 % 22/11/2021
Citadel Securities Group LP Delaware 0 190310 0 190310 190310 0.3 % 22/11/2021
Citadel Advisors LLC Delaware 0 3493833 0 3493833 3493833 4.7 % 22/11/2021
Citadel Advisors Holdings LP Delaware 0 3493833 0 3493833 3493833 4.7 % 22/11/2021
Citadel GP LLC Delaware 0 3493833 0 3493833 3493833 4.7 % 22/11/2021
Citadel Securities LLC Delaware 0 190310 0 190310 190310 0.3 % 22/11/2021
Citadel Advisors Holdings LP Delaware 0 3493833 0 3493833 3493833 4.7 % 22/11/2021
Kenneth Griffin U.S. Citizen 0 3684143 0 3684143 3684143 4.9 % 22/11/2021
Citadel Securities GP LLC Delaware 0 190310 0 190310 190310 0.3 % 22/11/2021
Citadel Securities LLC Delaware 0 190310 0 190310 190310 0.3 % 22/11/2021
BlackRock, Inc. Delaware 2691534 0 2796097 0 2796097 3.8 % 12/07/2021
Mark N. Lampert United States 0 7452331 0 7452331 7452331 10.1 % 08/07/2021
Biotechnology Value Trading Fund OS LP Cayman Islands 0 458157 0 458157 458157 0 % 08/07/2021
Biotechnology Value Fund, L.P. Delaware 0 3969986 0 3969986 3969986 5.4 % 08/07/2021
BVF I GP LLC Delaware 0 3969986 0 3969986 3969986 5.4 % 08/07/2021
Biotechnology Value Fund II, L.P. Delaware 0 2890839 0 2890839 2890839 3.9 % 08/07/2021
BVF II GP LLC Delaware 0 2890839 0 2890839 2890839 3.9 % 08/07/2021
BVF Partners OS Ltd. Cayman Islands 0 458157 0 458157 458157 0 % 08/07/2021
BVF GP HOLDINGS LLC Delaware 0 6860825 0 6860825 6860825 9.3 % 08/07/2021
BVF Partners L.P. Delaware 0 7452331 0 7452331 7452331 10.1 % 08/07/2021
BVF Inc. Delaware 0 7452331 0 7452331 7452331 10.1 % 08/07/2021
Biotechnology Value Fund, L.P. Delaware 0 3969986 0 3969986 3969986 5.4 % 08/07/2021
BVF I GP LLC Delaware 0 3969986 0 3969986 3969986 5.4 % 08/07/2021
Biotechnology Value Fund II, L.P. Delaware 0 2890839 0 2890839 2890839 3.9 % 08/07/2021
BVF II GP LLC Delaware 0 2890839 0 2890839 2890839 3.9 % 08/07/2021
Biotechnology Value Trading Fund OS LP Cayman Islands 0 458157 0 458157 458157 0 % 08/07/2021
BVF Partners OS Ltd. Cayman Islands 0 458157 0 458157 458157 0 % 08/07/2021
BVF GP HOLDINGS LLC Delaware 0 6860825 0 6860825 6860825 9.3 % 08/07/2021
BVF Partners L.P. Delaware 0 7452331 0 7452331 7452331 10.1 % 08/07/2021
BVF Inc. Delaware 0 7452331 0 7452331 7452331 10.1 % 08/07/2021
Mark N. Lampert United States 0 7452331 0 7452331 7452331 10.1 % 08/07/2021
Steven A. Cohen United States 0 1734364 0 1734364 1734364 2.5 % 16/02/2021
Point72 Hong Kong Limited Hong Kong 0 0 0 0 0 0 % 16/02/2021
Cubist Systematic Strategies, LLC Delaware 0 34364 0 34364 34364 0.1 % 16/02/2021
Point72 Asset Management, L.P. Delaware 0 1700000 0 1700000 1700000 2.4 % 16/02/2021
Point72 Hong Kong Limited Hong Kong 0 0 0 0 0 0 % 16/02/2021
Steven A. Cohen United States 0 1734364 0 1734364 1734364 2.5 % 16/02/2021
Cubist Systematic Strategies, LLC Delaware 0 34364 0 34364 34364 0.1 % 16/02/2021
Point72 Capital Advisors, Inc. Delaware 0 1700000 0 1700000 1700000 2.4 % 16/02/2021
Point72 Asset Management, L.P. Delaware 0 1700000 0 1700000 1700000 2.4 % 16/02/2021
Point72 Capital Advisors, Inc. Delaware 0 1700000 0 1700000 1700000 2.4 % 16/02/2021
(entities only Federated Hermes, Inc. 7442600 7442600 7442600 10.55 % 12/02/2021
J. Christopher Donahue 7442600 7442600 7442600 10.55 % 12/02/2021
Voting Shares Irrevocable Trust 7442600 7442600 7442600 10.55 % 12/02/2021
Thomas R. Donahue 7442600 7442600 7442600 10.55 % 12/02/2021
Rhodora J. Donahue 7442600 7442600 7442600 10.55 % 12/02/2021
The Vanguard Group Pennsylvania 0 142652 3494974 179720 3674694 5.21 % 10/02/2021
BlackRock, Inc. Delaware 5518816 0 5668400 0 5668400 8 % 28/01/2021
Adage Capital Partners GP, L.L.C. Delaware 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Adage Capital Partners GP, L.L.C. Delaware 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Adage Capital Advisors, L.L.C. Delaware 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Adage Capital Advisors, L.L.C. Delaware 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Robert Atchinson United States 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Adage Capital Partners, L.P. Delaware 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Adage Capital Partners, L.P. Delaware 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Phillip Gross United States 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Phillip Gross United States 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
Robert Atchinson United States 0 4000000 0 4000000 4000000 5.67 % 25/01/2021
PRIMECAP Management Company 10061500 14.26 % 08/10/2020
PRIMECAP Management Company 10061500 14.26 % 08/10/2020
Mark N. Lampert United States 0 7090638 0 7090638 7090638 10.1 % 26/05/2020
Biotechnology Value Fund II, L.P. Delaware 0 2766561 0 2766561 2766561 3.9 % 26/05/2020
BVF I GP LLC Delaware 0 3712340 0 3712340 3712340 5.3 % 26/05/2020
Biotechnology Value Fund, L.P. Delaware 0 3712340 0 3712340 3712340 5.3 % 26/05/2020
Mark N. Lampert United States 0 7090638 0 7090638 7090638 10.1 % 26/05/2020
BVF Inc. Delaware 0 7090638 0 7090638 7090638 10.1 % 26/05/2020
BVF Partners L.P. Delaware 0 7090638 0 7090638 7090638 10.1 % 26/05/2020
BVF GP HOLDINGS LLC Delaware 0 6478901 0 6478901 6478901 9.2 % 26/05/2020
BVF Partners OS Ltd. Cayman Islands 0 480432 0 480432 480432 0 % 26/05/2020
Biotechnology Value Trading Fund OS LP Cayman Islands 0 480432 0 480432 480432 0 % 26/05/2020
BVF II GP LLC Delaware 0 2766561 0 2766561 2766561 3.9 % 26/05/2020
Biotechnology Value Fund II, L.P. Delaware 0 2766561 0 2766561 2766561 3.9 % 26/05/2020
BVF I GP LLC Delaware 0 3712340 0 3712340 3712340 5.3 % 26/05/2020
Biotechnology Value Fund, L.P. Delaware 0 3712340 0 3712340 3712340 5.3 % 26/05/2020
BVF Partners OS Ltd. Cayman Islands 0 480432 0 480432 480432 0 % 26/05/2020
BVF GP HOLDINGS LLC Delaware 0 6478901 0 6478901 6478901 9.2 % 26/05/2020
BVF Partners L.P. Delaware 0 7090638 0 7090638 7090638 10.1 % 26/05/2020
BVF Inc. Delaware 0 7090638 0 7090638 7090638 10.1 % 26/05/2020
BVF II GP LLC Delaware 0 2766561 0 2766561 2766561 3.9 % 26/05/2020
Biotechnology Value Trading Fund OS LP Cayman Islands 0 480432 0 480432 480432 0 % 26/05/2020
Point72 Hong Kong Limited Hong Kong 0 1861 0 1861 1861 0.1 % 13/03/2020
Steven A. Cohen United States 0 3240046 0 3240046 3240046 5 % 13/03/2020
Point72 Asset Management, L.P. Delaware 0 3217300 0 3217300 3217300 5 % 13/03/2020
Point72 Capital Advisors, Inc. Delaware 0 3217300 0 3217300 3217300 5 % 13/03/2020
Cubist Systematic Strategies, LLC Delaware 0 20885 0 20885 20885 0.1 % 13/03/2020
Steven A. Cohen United States 0 3240046 0 3240046 3240046 5 % 13/03/2020
Point72 Asset Management, L.P. Delaware 0 3217300 0 3217300 3217300 5 % 13/03/2020
Point72 Capital Advisors, Inc. Delaware 0 3217300 0 3217300 3217300 5 % 13/03/2020
Cubist Systematic Strategies, LLC Delaware 0 20885 0 20885 20885 0.1 % 13/03/2020
Point72 Hong Kong Limited Hong Kong 0 1861 0 1861 1861 0.1 % 13/03/2020
PRIMECAP Management Company 9488000 15 % 10/01/2020
Wellington Group Holdings LLP Delaware 0 545408 0 581272 581272 1.08 % 08/11/2019
Wellington Investment Advisors Holdings LLP Delaware 0 545408 0 581272 581272 1.08 % 08/11/2019
Wellington Investment Advisors Holdings LLP Delaware 0 545408 0 581272 581272 1.08 % 08/11/2019
Wellington Group Holdings LLP Delaware 0 545408 0 581272 581272 1.08 % 08/11/2019
Wellington Management Group LLP Massachusetts 0 545408 0 581272 581272 1.08 % 08/11/2019
Wellington Management Group LLP Massachusetts 0 545408 0 581272 581272 1.08 % 08/11/2019
Biotechnology Value Trading Fund OS LP Cayman Islands 0 473006 0 473006 473006 0 % 25/06/2019
BVF Partners OS Ltd. Cayman Islands 0 473006 0 473006 473006 0 % 25/06/2019
BVF Inc. Delaware 0 6750482 0 6750482 6750482 13.1 % 25/06/2019
BVF Partners L.P. Delaware 0 6750482 0 6750482 6750482 13.1 % 25/06/2019
BVF Partners L.P. Delaware 0 6750482 0 6750482 6750482 13.1 % 25/06/2019
BVF Partners OS Ltd. Cayman Islands 0 473006 0 473006 473006 0 % 25/06/2019
Biotechnology Value Fund II, L.P. Delaware 0 2764620 0 2764620 2764620 5.4 % 25/06/2019
Biotechnology Value Fund, L.P. Delaware 0 3288378 0 3288378 3288378 6.4 % 25/06/2019
Biotechnology Value Trading Fund OS LP Cayman Islands 0 473006 0 473006 473006 0 % 25/06/2019
Biotechnology Value Fund II, L.P. Delaware 0 2764620 0 2764620 2764620 5.4 % 25/06/2019
BVF Inc. Delaware 0 6750482 0 6750482 6750482 13.1 % 25/06/2019
Mark N. Lampert United States 0 6750482 0 6750482 6750482 13.1 % 25/06/2019
Biotechnology Value Fund, L.P. Delaware 0 3288378 0 3288378 3288378 6.4 % 25/06/2019
Mark N. Lampert United States 0 6750482 0 6750482 6750482 13.1 % 25/06/2019
Wellington Management Company LLP Delaware 0 3357927 0 3475689 3475689 9.12 % 12/02/2019
Wellington Investment Advisors Holdings LLP Delaware 0 3381585 0 3708658 3708658 9.73 % 12/02/2019
Wellington Group Holdings LLP Delaware 0 3381585 0 3708658 3708658 9.73 % 12/02/2019
Wellington Management Group LLP Massachusetts 0 3381585 0 3708658 3708658 9.73 % 12/02/2019
Wellington Management Group LLP Massachusetts 0 3381585 0 3708658 3708658 9.73 % 12/02/2019
Wellington Investment Advisors Holdings LLP Delaware 0 3381585 0 3708658 3708658 9.73 % 12/02/2019
Wellington Group Holdings LLP Delaware 0 3381585 0 3708658 3708658 9.73 % 12/02/2019
Wellington Management Company LLP Delaware 0 3357927 0 3475689 3475689 9.12 % 12/02/2019
BVF Inc. Delaware 0 2019000 0 2019000 2019000 5.6 % 04/09/2018
Biotechnology Value Trading Fund OS LP Cayman Islands 0 143650 0 143650 143650 0 % 04/09/2018
Biotechnology Value Fund II, L.P. Delaware 0 724237 0 724237 724237 2 % 04/09/2018
Biotechnology Value Fund, L.P. Delaware 0 970400 0 970400 970400 2.7 % 04/09/2018
Mark N. Lampert United States 0 2019000 0 2019000 2019000 5.6 % 04/09/2018
BVF Inc. Delaware 0 2019000 0 2019000 2019000 5.6 % 04/09/2018
BVF Partners L.P. Delaware 0 2019000 0 2019000 2019000 5.6 % 04/09/2018
BVF Partners OS Ltd. Cayman Islands 0 143650 0 143650 143650 0 % 04/09/2018
Biotechnology Value Trading Fund OS LP Cayman Islands 0 143650 0 143650 143650 0 % 04/09/2018
Biotechnology Value Fund II, L.P. Delaware 0 724237 0 724237 724237 2 % 04/09/2018
Biotechnology Value Fund, L.P. Delaware 0 970400 0 970400 970400 2.7 % 04/09/2018
Mark N. Lampert United States 0 2019000 0 2019000 2019000 5.6 % 04/09/2018
BVF Partners L.P. Delaware 0 2019000 0 2019000 2019000 5.6 % 04/09/2018
BVF Partners OS Ltd. Cayman Islands 0 143650 0 143650 143650 0 % 04/09/2018
Viking Long Fund Master Ltd. _____________________________________________________________________________ Cayman Islands 487787 0 487787 487787 1.4 % 14/02/2018
Viking Long Fund GP LLC _____________________________________________________________________________ Delaware 487787 0 487787 487787 1.4 % 14/02/2018
Viking Global Equities LP _____________________________________________________________________________ Delaware 394158 0 394158 394158 1.1 % 14/02/2018
VGE III Portfolio Ltd. _____________________________________________________________________________ Cayman Islands 738616 0 738616 738616 2.1 % 14/02/2018
Viking Global Performance LLC _____________________________________________________________________________ Delaware 1155894 0 1155894 1155894 3.3 % 14/02/2018
Viking Global Investors LP _____________________________________________________________________________ Delaware 1643681 0 1643681 1643681 4.6 % 14/02/2018
Viking Global Equities II LP _____________________________________________________________________________ Delaware 23120 0 23120 23120 0.1 % 14/02/2018
Rose S. Shabet _____________________________________________________________________________ United States 1643681 0 1643681 1643681 4.6 % 14/02/2018
David C. Ott _____________________________________________________________________________ United States 1643681 0 1643681 1643681 4.6 % 14/02/2018
O. Andreas Halvorsen _____________________________________________________________________________ Norway 1643681 0 1643681 1643681 4.6 % 14/02/2018
Jason Lettmann United States 0 0 0 0 0 0 % 14/02/2018
Robert D. Pavey United States 0 0 0 0 0 0 % 14/02/2018
Henry Plain United States 0 0 0 0 0 0 % 14/02/2018
Morgenthaler Venture Partners IX, L.P. Delaware 0 0 0 0 0 0 % 14/02/2018
Morgenthaler Management Partners IX, LLC Delaware 0 0 0 0 0 0 % 14/02/2018
Robert C. Bellas, Jr. United States 0 0 0 0 0 0 % 14/02/2018
Ralph E. Christoffersen United States 0 0 0 0 0 0 % 14/02/2018
Gary R. Little United States 0 0 0 0 0 0 % 14/02/2018
Rebecca Lynn United States 0 0 0 0 0 0 % 14/02/2018
Gary J. Morgenthaler United States 0 0 0 0 0 0 % 14/02/2018
Phillip Gross United States 0 1500000 0 1500000 1500000 4.23 % 13/02/2018
Robert Atchinson United States 0 1500000 0 1500000 1500000 4.23 % 13/02/2018
Adage Capital Partners, L.P. Delaware 0 1500000 0 1500000 1500000 4.23 % 13/02/2018
Adage Capital Partners GP, L.L.C. Delaware 0 1500000 0 1500000 1500000 4.23 % 13/02/2018
Adage Capital Advisors, L.L.C. Delaware 0 1500000 0 1500000 1500000 4.23 % 13/02/2018
Hawkes Bay Master Investors L.P. Cayman Islands 0 883558 0 883558 883558 2.49 % 08/02/2018
Wellington Investment Advisors Holdings LLP Delaware 0 4091982 0 4524551 4524551 12.75 % 08/02/2018
Wellington Management Company LLP Delaware 0 4068468 0 4343923 4343923 12.24 % 08/02/2018
Wellington Management Group LLP Massachusetts 0 4091982 0 4524551 4524551 12.75 % 08/02/2018
Wellington Group Holdings LLP Delaware 0 4091982 0 4524551 4524551 12.75 % 08/02/2018
BlackRock, Inc. Delaware 2811159 0 2886275 0 2886275 8.1 % 01/02/2018
Adage Capital Advisors, L.L.C. Delaware 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Adage Capital Partners, L.P. Delaware 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Adage Capital Advisors, L.L.C. Delaware 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Phillip Gross United States 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Robert Atchinson United States 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Robert Atchinson United States 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Phillip Gross United States 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Adage Capital Partners, L.P. Delaware 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Adage Capital Partners GP, L.L.C. Delaware 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
Adage Capital Partners GP, L.L.C. Delaware 0 3447873 0 3447873 3447873 9.72 % 28/09/2017
O. Andreas Halvorsen _____________________________________________________________________________ Norway 2420317 0 2420317 2420317 6.9 % 10/07/2017
Viking Long Fund Master Ltd. _____________________________________________________________________________ Cayman Islands 781646 0 781646 781646 2.2 % 10/07/2017
Viking Long Fund GP LLC _____________________________________________________________________________ Delaware 781646 0 781646 781646 2.2 % 10/07/2017
VGE III Portfolio Ltd. _____________________________________________________________________________ Cayman Islands 1056942 0 1056942 1056942 3 % 10/07/2017
Viking Global Equities II LP _____________________________________________________________________________ Delaware 32773 0 32773 32773 0.1 % 10/07/2017
Viking Global Equities LP _____________________________________________________________________________ Delaware 548956 0 548956 548956 1.6 % 10/07/2017
Viking Global Performance LLC _____________________________________________________________________________ Delaware 1638671 0 1638671 1638671 4.6 % 10/07/2017
Viking Global Investors LP _____________________________________________________________________________ Delaware 2420317 0 2420317 2420317 6.9 % 10/07/2017
Rose S. Shabet _____________________________________________________________________________ United States 2420317 0 2420317 2420317 6.9 % 10/07/2017
David C. Ott _____________________________________________________________________________ United States 2420317 0 2420317 2420317 6.9 % 10/07/2017
Viking Long Fund Master Ltd. _____________________________________________________________________________ Cayman Islands 781646 0 781646 781646 2.2 % 10/07/2017
Rose S. Shabet _____________________________________________________________________________ United States 2420317 0 2420317 2420317 6.9 % 10/07/2017
David C. Ott _____________________________________________________________________________ United States 2420317 0 2420317 2420317 6.9 % 10/07/2017
O. Andreas Halvorsen _____________________________________________________________________________ Norway 2420317 0 2420317 2420317 6.9 % 10/07/2017
Viking Long Fund GP LLC _____________________________________________________________________________ Delaware 781646 0 781646 781646 2.2 % 10/07/2017
VGE III Portfolio Ltd. _____________________________________________________________________________ Cayman Islands 1056942 0 1056942 1056942 3 % 10/07/2017
Viking Global Equities II LP _____________________________________________________________________________ Delaware 32773 0 32773 32773 0.1 % 10/07/2017
Viking Global Equities LP _____________________________________________________________________________ Delaware 548956 0 548956 548956 1.6 % 10/07/2017
Viking Global Performance LLC _____________________________________________________________________________ Delaware 1638671 0 1638671 1638671 4.6 % 10/07/2017
Viking Global Investors LP _____________________________________________________________________________ Delaware 2420317 0 2420317 2420317 6.9 % 10/07/2017
Wellington Investment Advisors Holdings LLP Delaware 0 2780800 0 3054801 3054801 14 % 10/03/2017
Wellington Group Holdings LLP Delaware 0 2780800 0 3054801 3054801 14 % 10/03/2017
Wellington Investment Advisors Holdings LLP Delaware 0 2780800 0 3054801 3054801 14 % 10/03/2017
Wellington Management Group LLP Massachusetts 0 2780800 0 3054801 3054801 14 % 10/03/2017
Wellington Management Company LLP Delaware 0 2780800 0 2952361 2952361 13.53 % 10/03/2017
Wellington Management Group LLP Massachusetts 0 2780800 0 3054801 3054801 14 % 10/03/2017
Wellington Group Holdings LLP Delaware 0 2780800 0 3054801 3054801 14 % 10/03/2017
Wellington Management Company LLP Delaware 0 2780800 0 2952361 2952361 13.53 % 10/03/2017
Hawkes Bay Master Investors Cayman Islands 0 1094443 0 1094443 1094443 5.28 % 06/03/2017
Viking Long Fund GP LLC _____________________________________________________________________________ Delaware 465936 0 465936 465936 2.2 % 21/02/2017
Viking Global Investors LP _____________________________________________________________________________ Delaware 1607936 0 1607936 1607936 7.8 % 21/02/2017
Viking Global Performance LLC _____________________________________________________________________________ Delaware 1142000 0 1142000 1142000 5.5 % 21/02/2017
Viking Global Equities LP _____________________________________________________________________________ Delaware 388280 0 388280 388280 1.9 % 21/02/2017
Viking Global Equities II LP _____________________________________________________________________________ Delaware 22840 0 22840 22840 0.1 % 21/02/2017
VGE III Portfolio Ltd. _____________________________________________________________________________ Cayman Islands 730880 0 730880 730880 3.5 % 21/02/2017
Viking Long Fund GP LLC _____________________________________________________________________________ Delaware 465936 0 465936 465936 2.2 % 21/02/2017
Viking Long Fund Master Ltd. _____________________________________________________________________________ Cayman Islands 465936 0 465936 465936 2.2 % 21/02/2017
O. Andreas Halvorsen _____________________________________________________________________________ Norway 1607936 0 1607936 1607936 7.8 % 21/02/2017
David C. Ott _____________________________________________________________________________ United States 1607936 0 1607936 1607936 7.8 % 21/02/2017
Daniel S. Sundheim _____________________________________________________________________________ United States 1607936 0 1607936 1607936 7.8 % 21/02/2017
Viking Global Investors LP _____________________________________________________________________________ Delaware 1607936 0 1607936 1607936 7.8 % 21/02/2017
Viking Global Performance LLC _____________________________________________________________________________ Delaware 1142000 0 1142000 1142000 5.5 % 21/02/2017
Viking Global Equities LP _____________________________________________________________________________ Delaware 388280 0 388280 388280 1.9 % 21/02/2017
Viking Global Equities II LP _____________________________________________________________________________ Delaware 22840 0 22840 22840 0.1 % 21/02/2017
VGE III Portfolio Ltd. _____________________________________________________________________________ Cayman Islands 730880 0 730880 730880 3.5 % 21/02/2017
Daniel S. Sundheim _____________________________________________________________________________ United States 1607936 0 1607936 1607936 7.8 % 21/02/2017
David C. Ott _____________________________________________________________________________ United States 1607936 0 1607936 1607936 7.8 % 21/02/2017
O. Andreas Halvorsen _____________________________________________________________________________ Norway 1607936 0 1607936 1607936 7.8 % 21/02/2017
Viking Long Fund Master Ltd. _____________________________________________________________________________ Cayman Islands 465936 0 465936 465936 2.2 % 21/02/2017
Phillip Gross United States 0 3635069 0 3635069 3635069 17.53 % 09/02/2017
Robert Atchinson United States 0 3635069 0 3635069 3635069 17.53 % 09/02/2017
Adage Capital Advisors, L.L.C. Delaware 0 3635069 0 3635069 3635069 17.53 % 09/02/2017
Adage Capital Partners GP, L.L.C. Delaware 0 3635069 0 3635069 3635069 17.53 % 09/02/2017
Adage Capital Partners, L.P. Delaware 0 3635069 0 3635069 3635069 17.53 % 09/02/2017
Incyte Corporation 1720430 7.4 % 31/01/2017
Abigail P. Johnson United States of America 0 0 357508 0 357508 1.886 % 10/08/2016
Abigail P. Johnson United States of America 0 0 357508 0 357508 1.886 % 10/08/2016
FMR LLC Delaware 250 0 357508 0 357508 1.886 % 10/08/2016
FMR LLC Delaware 250 0 357508 0 357508 1.886 % 10/08/2016
Adage Capital Partners GP, L.L.C. Delaware 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Phillip Gross United States 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Robert Atchinson United States 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Adage Capital Advisors, L.L.C. Delaware 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Adage Capital Partners GP, L.L.C. Delaware 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Adage Capital Partners, L.P. Delaware 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Phillip Gross United States 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Robert Atchinson United States 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Adage Capital Advisors, L.L.C. Delaware 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Adage Capital Partners, L.P. Delaware 0 3135069 0 3135069 3135069 17.29 % 16/02/2016
Jason Lettmann United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Robert D. Pavey United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Henry Plain United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Scott D. Walters United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Robert C. Bellas, Jr. United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Gary R. Little United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Gary J. Morgenthaler United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Ralph E. Christoffersen United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Morgenthaler Venture Partners IX, L.P. Delaware 2161915 2161915 2161915 2161915 2161915 12.1 % 17/02/2015
Morgenthaler Management Partners IX, LLC Delaware 2161915 2161915 2161915 2161915 2161915 12.1 % 17/02/2015
Rebecca Lynn United States 0 2161915 0 2161915 2161915 12.1 % 17/02/2015
Edward C. Johnson 3d United States of America 0 0 2141500 0 2141500 11.976 % 10/11/2014
Select Biotechnology Portfolio Massachusetts 1378700 0 0 0 1378700 7.71 % 10/11/2014
Abigail P. Johnson United States of America 0 0 2141500 0 2141500 11.976 % 10/11/2014
FMR LLC Delaware 15000 0 2141500 0 2141500 11.976 % 10/11/2014
FMR LLC Delaware 15000 0 2141500 0 2141500 11.976 % 10/11/2014
Edward C. Johnson 3d United States of America 0 0 2141500 0 2141500 11.976 % 10/11/2014
Select Biotechnology Portfolio Massachusetts 1378700 0 0 0 1378700 7.71 % 10/11/2014
Abigail P. Johnson United States of America 0 0 2141500 0 2141500 11.976 % 10/11/2014
Adage Capital Partners GP, L.L.C. Delaware 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Adage Capital Partners, L.P. Delaware 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Adage Capital Partners GP, L.L.C. Delaware 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Phillip Gross United States 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Robert Atchinson United States 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Adage Capital Advisors, L.L.C. Delaware 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Robert Atchinson United States 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Adage Capital Advisors, L.L.C. Delaware 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Adage Capital Partners, L.P. Delaware 0 2765675 0 2765675 2765675 15.47 % 22/10/2014
Phillip Gross United States 0 2765675 0 2765675 2765675 15.47 % 22/10/2014

Senat trading

Bureau Date de la transaction Date de réception Type Amount Commentaire

Senat Divulgation

Représentant Date de la transaction Date de divulgation Type Amount District