| V. Gordon Clemons |
|
1389837 |
0 |
1389837 |
0 |
1389837 |
7.87 % |
14/02/2022 |
| KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC95-4575414 |
|
1425843 |
431387 |
1566118 |
431387 |
1997505 |
11.27 % |
11/02/2022 |
| 26-0385758 |
Delaware |
902210 |
0 |
902210 |
0 |
902210 |
5.11 % |
11/02/2022 |
| 2 |
|
0 |
6494036 |
0 |
6494036 |
6494036 |
12 % |
10/02/2022 |
| 2 |
|
215937 |
6494036 |
215937 |
6494036 |
6709973 |
38 % |
10/02/2022 |
| The Vanguard Group - 23-1945930 |
Pennsylvania |
0 |
17024 |
1073223 |
25624 |
1098847 |
6.2 % |
09/02/2022 |
| (1) BlackRock, Inc. |
Delaware |
1481515 |
0 |
1497827 |
0 |
1497827 |
8.5 % |
01/02/2022 |
| KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC95-4575414 |
A California |
1369015 |
481080 |
1369015 |
481080 |
1850095 |
10.29 % |
12/07/2021 |
| V. Gordon Clemons |
|
1560050 |
0 |
1560050 |
0 |
1560050 |
8.72 % |
12/02/2021 |
| 26-0385758 |
Delaware |
1063510 |
0 |
1063510 |
0 |
1063510 |
5.95 % |
10/02/2021 |
| 13-3127734 |
Delaware |
1063510 |
0 |
1063510 |
0 |
1063510 |
5.95 % |
10/02/2021 |
| KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC95-4575414 |
|
892014 |
481080 |
892014 |
481080 |
1373094 |
7.67 % |
10/02/2021 |
| The Vanguard Group - 23-1945930 |
Pennsylvania |
0 |
20485 |
988684 |
28223 |
1016907 |
5.68 % |
10/02/2021 |
| Jeffrey J. Michael |
|
227937 |
6619036 |
227937 |
0 |
6846973 |
38.3 % |
08/02/2021 |
| Corstar Holdings, Inc. |
|
0 |
6619036 |
0 |
0 |
6619036 |
37.02 % |
08/02/2021 |
| (1) BlackRock, Inc. |
Delaware |
1490661 |
0 |
1511994 |
0 |
1511994 |
8.4 % |
29/01/2021 |
| of 5 Pages |
United States of America |
1712146 |
0 |
1712146 |
0 |
1712146 |
9.43 % |
19/02/2020 |
| 26-0385758 |
Delaware |
1315410 |
0 |
1315410 |
0 |
1315410 |
7.25 % |
12/02/2020 |
| 13-3127734 |
Delaware |
1315410 |
0 |
1315410 |
0 |
1315410 |
7.25 % |
12/02/2020 |
| The Vanguard Group - 23-1945930 |
Pennsylvania |
19413 |
800 |
1085345 |
18563 |
1103908 |
6.03 % |
12/02/2020 |
| Corstar Holdings, Inc. |
Minnesota |
0 |
6738556 |
0 |
0 |
6738556 |
37.2 % |
10/02/2020 |
| Jeffrey J. Michael |
United States |
232485 |
6738556 |
232485 |
0 |
6971041 |
38.5 % |
10/02/2020 |
| (1) BlackRock, Inc. |
Delaware |
1406829 |
0 |
1425910 |
0 |
1425910 |
7.8 % |
05/02/2020 |
| 13-3127734 |
Delaware |
1416300 |
0 |
0 |
221006109 |
1416300 |
7.57 % |
12/02/2019 |
| 26-0385758 |
Delaware |
1416300 |
0 |
0 |
221006109 |
1416300 |
7.57 % |
12/02/2019 |
| of 4 Pages |
United States America |
1861612 |
0 |
1861612 |
0 |
1861612 |
9.96 % |
07/02/2019 |
| (1) BlackRock, Inc. |
Delaware |
1417996 |
0 |
1437286 |
0 |
1437286 |
7.7 % |
04/02/2019 |
| V. Gordon Clemons |
United States of America |
1990546 |
0 |
1990546 |
0 |
1990546 |
10.5 % |
16/02/2018 |
| 13-3127734 |
Delaware |
1473400 |
0 |
1473400 |
0 |
1473400 |
7.82 % |
13/02/2018 |
| 26-0385758 |
Delaware |
1473400 |
0 |
1473400 |
0 |
1473400 |
7.82 % |
13/02/2018 |
| (1) BlackRock, Inc. |
Delaware |
1277318 |
0 |
1301105 |
0 |
1301105 |
6.9 % |
29/01/2018 |
| of 4 Pages |
United States of America |
1884880 |
0 |
1884880 |
0 |
1884880 |
9.8 % |
16/02/2017 |
| 26-0385758 |
Delaware |
1457800 |
0 |
1545363 |
35537 |
1580900 |
8.22 % |
14/02/2017 |
| 13-3127734 |
Delaware |
1457800 |
0 |
1545363 |
35537 |
1580900 |
8.22 % |
14/02/2017 |
| Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
717968 |
0 |
0 |
982906 |
5.04 % |
09/02/2017 |
| Wellington Management Company LLP |
Delaware |
0 |
716470 |
0 |
0 |
976308 |
5.01 % |
09/02/2017 |
| Wellington Group Holdings LLP |
Delaware |
0 |
717968 |
0 |
0 |
982906 |
5.04 % |
09/02/2017 |
| Wellington Management Group LLP |
Massachusetts |
0 |
717968 |
0 |
0 |
982906 |
5.04 % |
09/02/2017 |
| Jeffrey J. Michael. |
United States |
237153 |
7174134 |
237153 |
0 |
7411287 |
38.02 % |
08/02/2017 |
| Corstar Holdings, Inc. |
Minnesota |
0 |
7174134 |
0 |
0 |
7174134 |
36.8 % |
08/02/2017 |
| (1) BlackRock, Inc. |
Delaware |
1238953 |
0 |
1263291 |
0 |
1263291 |
6.5 % |
23/01/2017 |
| Jeffrey J. Michael. |
United States |
238406 |
7369134 |
238406 |
0 |
7607540 |
38.54 % |
02/02/2016 |
| Corstar Holdings, Inc. |
Minnesota |
0 |
7369134 |
0 |
0 |
7369134 |
37.43 % |
02/02/2016 |
| (1) BlackRock, Inc. |
Delaware |
1004286 |
0 |
1029534 |
0 |
1029534 |
5.2 % |
28/01/2016 |
| (1) BlackRock, Inc. |
Delaware |
955587 |
0 |
980973 |
0 |
980973 |
4.9 % |
10/07/2015 |
| Jeffrey J. Michael. |
Minnesota |
237250 |
7369134 |
237250 |
0 |
7606384 |
36.83 % |
20/05/2015 |
| Corstar Holdings, Inc. |
Minnesota |
0 |
7369134 |
0 |
0 |
7369134 |
35.68 % |
20/05/2015 |
| FMR LLC |
Delaware |
79302 |
0 |
1116002 |
0 |
1116002 |
5.404 % |
13/02/2015 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1116002 |
0 |
1116002 |
5.404 % |
13/02/2015 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1116002 |
0 |
1116002 |
5.404 % |
13/02/2015 |
| 26-0385758 |
Delaware |
1229300 |
0 |
1302000 |
0 |
1302000 |
6.36 % |
12/02/2015 |
| 13-3127734 |
Delaware |
1229300 |
0 |
1302000 |
0 |
1302000 |
6.36 % |
12/02/2015 |
| (1) BlackRock, Inc. |
Delaware |
1104090 |
0 |
1132049 |
0 |
1132049 |
5.5 % |
02/02/2015 |
| 04-2683227 |
Massachusetts |
0 |
828365 |
0 |
0 |
1079723 |
5.16 % |
14/02/2014 |
| 26-0385758 |
Delaware |
1078900 |
0 |
0 |
221006109 |
1078900 |
5.15 % |
13/02/2014 |
| 13-3127734 |
Delaware |
1078900 |
0 |
0 |
221006109 |
1078900 |
5.15 % |
13/02/2014 |
| 13G |
Minnesota |
0 |
7469134 |
0 |
7469134 |
7469134 |
11 % |
04/02/2014 |
| 13G |
United States |
232000 |
7469134 |
232000 |
7469134 |
7701134 |
11 % |
04/02/2014 |
| (1) BlackRock, Inc. |
Delaware |
1361468 |
0 |
1392336 |
0 |
1392336 |
6.7 % |
28/01/2014 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
673481 |
0 |
673481 |
6.007 % |
14/02/2013 |
| FMR LLC |
Delaware |
4127 |
0 |
673481 |
0 |
673481 |
6.007 % |
14/02/2013 |
| HealthCor Long Master GP, LLC |
Delaware |
0 |
10795 |
0 |
10795 |
10795 |
0.1 % |
14/02/2013 |
| HealthCor Offshore GP, LLC |
Delaware |
0 |
559965 |
0 |
559965 |
559965 |
5.17 % |
14/02/2013 |
| HealthCor Offshore Master Fund, L.P. |
Cayman Islands |
0 |
559965 |
0 |
559965 |
559965 |
5.17 % |
14/02/2013 |
| HealthCor Associates, LLC |
Delaware |
0 |
570760 |
0 |
570760 |
570760 |
5.27 % |
14/02/2013 |
| HealthCor Group, LLC |
Delaware |
0 |
570760 |
0 |
570760 |
570760 |
5.27 % |
14/02/2013 |
| Arthur Cohen |
United States |
0 |
570760 |
0 |
570760 |
570760 |
5.27 % |
14/02/2013 |
| Joseph Healey |
United States |
0 |
570760 |
0 |
570760 |
570760 |
5.27 % |
14/02/2013 |
| HealthCor Management, L.P. |
Delaware |
0 |
570760 |
0 |
570760 |
570760 |
5.27 % |
14/02/2013 |
| HealthCor Long Offshore Master Fund, L.P. |
Cayman Islands |
0 |
10795 |
0 |
10795 |
10795 |
0.1 % |
14/02/2013 |
| HealthCor Hybrid Offshore GP, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2013 |
| HealthCor Hybrid Offshore Master Fund, L.P. |
Cayman Islands |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2013 |
| FMR LLC |
Delaware |
0 |
0 |
776826 |
0 |
776826 |
6.794 % |
14/02/2012 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
776826 |
0 |
776826 |
6.794 % |
14/02/2012 |
| HealthCor Management, L.P. |
Delaware |
0 |
737500 |
0 |
737500 |
737500 |
6.5 % |
13/02/2012 |
| HealthCor Associates, LLC |
Delaware |
0 |
737500 |
0 |
737500 |
737500 |
6.5 % |
13/02/2012 |
| HealthCor Offshore Master Fund, L.P. |
Cayman Islands |
0 |
498795 |
0 |
498795 |
498795 |
4.4 % |
13/02/2012 |
| Corstar Holdings, Inc. |
Minnesota |
0 |
3850001 |
0 |
0 |
3850001 |
33.67 % |
31/01/2012 |
| Jeffrey J. Michael. |
Minnesota |
119327 |
3850001 |
119327 |
0 |
3969328 |
34.72 % |
31/01/2012 |
| Page 2 of 18 Pages |
Delaware |
0 |
633122 |
0 |
633122 |
633122 |
5.54 % |
07/12/2011 |
| (1) BlackRock, Inc. |
Delaware |
572898 |
0 |
572898 |
0 |
572898 |
4.93 % |
08/07/2011 |
| (1) BlackRock, Inc. |
Delaware |
593141 |
0 |
593141 |
0 |
593141 |
5.02 % |
03/02/2011 |
| BlackRock for purposes of Schedule 13G filings. |
Delaware |
603036 |
0 |
603036 |
0 |
603036 |
4.99 % |
09/04/2010 |
| HealthCor Offshore Master Fund, L.P. |
Delaware |
0 |
591988 |
0 |
591988 |
591988 |
4.9 % |
12/02/2010 |
| HealthCor Hybrid Offshore GP, LLC |
Delaware |
0 |
136440 |
0 |
136440 |
136440 |
1.13 % |
12/02/2010 |
| HealthCor Group, LLC |
Delaware |
0 |
1000000 |
0 |
1000000 |
1000000 |
8.27 % |
12/02/2010 |
| HealthCor Hybrid Offshore Master Fund, L.P. |
Delaware |
0 |
136440 |
0 |
136440 |
136440 |
1.13 % |
12/02/2010 |
| HealthCor Hybrid Offshore, Ltd. |
Delaware |
0 |
136440 |
0 |
136440 |
136440 |
1.13 % |
12/02/2010 |
| HealthCor Offshore GP, LLC |
Delaware |
0 |
591988 |
0 |
591988 |
591988 |
4.9 % |
12/02/2010 |
| HealthCor Offshore, Ltd. |
Delaware |
0 |
591988 |
0 |
591988 |
591988 |
4.9 % |
12/02/2010 |
| HealthCor Management, L.P. |
Delaware |
0 |
1000000 |
0 |
1000000 |
1000000 |
8.27 % |
12/02/2010 |
| Joseph Healey |
Delaware |
0 |
1000000 |
0 |
1000000 |
1000000 |
8.27 % |
12/02/2010 |
| Arthur Cohen |
Delaware |
0 |
1000000 |
0 |
1000000 |
1000000 |
8.27 % |
12/02/2010 |
| HealthCor, L.P. |
Delaware |
0 |
271572 |
0 |
271572 |
271572 |
2.25 % |
12/02/2010 |
| HealthCor Capital, L.P. |
Delaware |
0 |
271572 |
0 |
271572 |
271572 |
2.25 % |
12/02/2010 |
| HealthCor Associates, LLC |
Delaware |
0 |
1000000 |
0 |
1000000 |
1000000 |
8.27 % |
12/02/2010 |
| 04-2683227 |
Massachusetts |
0 |
657314 |
0 |
0 |
859168 |
7 % |
12/02/2010 |
| BlackRock for purposes of Schedule 13G filings. |
Delaware |
627261 |
0 |
627261 |
0 |
627261 |
5.11 % |
29/01/2010 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
491916 |
0 |
491916 |
3.666 % |
17/02/2009 |
| FMR LLC |
Delaware |
0 |
0 |
491916 |
0 |
491916 |
3.666 % |
17/02/2009 |
| 04-2683227 |
Massachusetts |
0 |
569002 |
0 |
0 |
718026 |
5.35 % |
17/02/2009 |
| Cohen |
or Place of Organization: |
0 |
0 |
0 |
700000 |
700000 |
5.01 % |
03/07/2007 |
| 20-2893681 |
or Place of Organization: |
0 |
0 |
0 |
700000 |
700000 |
5.01 % |
03/07/2007 |
| Healey |
or Place of Organization: |
0 |
0 |
0 |
700000 |
700000 |
5.01 % |
03/07/2007 |
| Corstar |
Minnesota |
4050001 |
0 |
4050001 |
0 |
4050001 |
28.8 % |
20/03/2007 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
848711 |
0 |
848711 |
6.039 % |
14/02/2007 |
| FMR Corp. |
Delaware |
0 |
0 |
848711 |
0 |
848711 |
6.039 % |
14/02/2007 |
| 04-2683227 |
Massachusetts |
0 |
23745 |
0 |
0 |
44595 |
0.48 % |
14/02/2007 |
| 04-2718215 |
WITH: |
521609 |
0 |
521609 |
0 |
521609 |
5.6 % |
14/02/2006 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1002295 |
0 |
1002295 |
10.351 % |
14/02/2006 |
| FMR Corp. |
Delaware |
1000 |
0 |
1002295 |
0 |
1002295 |
10.351 % |
14/02/2006 |
| 51-0504477 |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
19/01/2006 |
| 04-2718215 |
WITH: |
552050 |
0 |
552050 |
0 |
552050 |
5.4 % |
14/02/2005 |
| FMR Corp. |
Delaware |
74214 |
0 |
1424863 |
0 |
1424863 |
13.628 % |
14/02/2005 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1424863 |
0 |
1424863 |
13.628 % |
14/02/2005 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1424863 |
0 |
1424863 |
13.628 % |
14/02/2005 |
| 51-0504477 |
Delaware |
572150 |
5200 |
577350 |
0 |
577350 |
5.52 % |
20/01/2005 |
| FMR Corp. |
Delaware |
147300 |
0 |
1609150 |
0 |
1609150 |
15.205 % |
17/02/2004 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1609150 |
0 |
1609150 |
15.205 % |
17/02/2004 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1609150 |
0 |
1609150 |
15.205 % |
17/02/2004 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1636850 |
0 |
1636850 |
15.255 % |
13/02/2003 |
| FMR Corp. |
Delaware |
150000 |
0 |
1636850 |
0 |
1636850 |
15.255 % |
13/02/2003 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1636850 |
0 |
1636850 |
15.255 % |
13/02/2003 |
| 04-2683227 |
Massachusetts |
0 |
349150 |
0 |
546400 |
546400 |
5.09 % |
12/02/2003 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1653325 |
0 |
1653325 |
14.989 % |
14/02/2002 |
| FMR Corp. |
Commonwealth of Massachusetts |
3300 |
0 |
1653325 |
0 |
1653325 |
14.989 % |
14/02/2002 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1653325 |
0 |
1653325 |
14.989 % |
14/02/2002 |
| 04-2683227 |
Massachusetts |
0 |
373750 |
0 |
591750 |
591750 |
5.36 % |
12/02/2002 |
| FMR Corp. |
Commonwealth of Massachusetts |
0 |
0 |
1593225 |
0 |
1593225 |
14.338 % |
10/10/2001 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1593225 |
0 |
1593225 |
14.338 % |
10/10/2001 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1593225 |
0 |
1593225 |
14.338 % |
10/10/2001 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
1469325 |
0 |
1469325 |
19.622 % |
10/09/2001 |
| FMR Corp. |
Commonwealth of Massachusetts |
0 |
0 |
1469325 |
0 |
1469325 |
19.622 % |
10/09/2001 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
1469325 |
0 |
1469325 |
19.622 % |
10/09/2001 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
796540 |
0 |
796540 |
10.464 % |
13/02/2001 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
796540 |
0 |
796540 |
10.464 % |
13/02/2001 |
| FMR Corp. |
Commonwealth of Massachusetts |
0 |
0 |
796540 |
0 |
796540 |
10.464 % |
13/02/2001 |
| 04-2683227 |
Massachusetts |
0 |
244400 |
0 |
391900 |
391900 |
5.15 % |
13/02/2001 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
766420 |
0 |
766420 |
10.017 % |
10/10/2000 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
766420 |
0 |
766420 |
10.017 % |
10/10/2000 |
| FMR Corp. |
Commonwealth of Massachusetts |
0 |
0 |
766420 |
0 |
766420 |
10.017 % |
10/10/2000 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
752000 |
0 |
752000 |
9.265 % |
11/02/2000 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
752000 |
0 |
752000 |
9.265 % |
11/02/2000 |
| FMR Corp. |
Commonwealth of Massachusetts |
0 |
0 |
752000 |
0 |
752000 |
9.265 % |
11/02/2000 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
220000 |
0 |
220000 |
5.406 % |
12/02/1999 |
| FMR Corp. |
Commonwealth of Massachusetts |
0 |
0 |
220000 |
0 |
220000 |
5.406 % |
12/02/1999 |
| Edward C. Johnson 3d |
United States of America |
0 |
0 |
220000 |
0 |
220000 |
5.406 % |
12/02/1999 |
| 13-3964629 |
DELAWARE |
0 |
0 |
240500 |
0 |
240500 |
5.11 % |
20/02/1998 |
| 04-2683227 |
Massachusetts |
0 |
219600 |
0 |
385100 |
385100 |
9.2 % |
10/02/1998 |
| (41-0498850) |
Minnesota |
1225000 |
0 |
1225000 |
0 |
1225000 |
26 % |
03/12/1996 |