FINN MANAGEMENT GP LLC |
DELAWARE |
1180000 |
0 |
1180000 |
0 |
1180000 |
4 % |
14/11/2024 |
BRIAN A. FINN |
USA |
1180000 |
0 |
1180000 |
0 |
1180000 |
4 % |
14/11/2024 |
FINDELL CAPITAL MANAGEMENT LLC |
DELAWARE |
1180000 |
0 |
1180000 |
0 |
1180000 |
4 % |
14/11/2024 |
FINDELL CAPITAL PARTNERS, LP |
DELAWARE |
1180000 |
0 |
1180000 |
0 |
1180000 |
4 % |
14/11/2024 |
The Vanguard Group |
Pennsylvania |
0 |
0 |
1271116 |
12226 |
1283342 |
4.36 % |
12/11/2024 |
The Vanguard Group |
Pennsylvania |
0 |
0 |
1271116 |
12226 |
1283342 |
4.36 % |
04/11/2024 |
BlackRock, Inc. |
Delaware |
1071753 |
0 |
1122443 |
0 |
1122443 |
3.9 % |
08/07/2024 |
Scott Green |
United States |
0 |
2396187 |
0 |
2396187 |
2396187 |
8.45 % |
14/02/2024 |
8 Knots GP, LP |
Delaware |
0 |
1554417 |
0 |
1554417 |
1554417 |
5.48 % |
14/02/2024 |
8 Knots Management, LLC |
Delaware |
0 |
2396187 |
0 |
2396187 |
2396187 |
8.45 % |
14/02/2024 |
8 Knots Fund, LP |
Delaware |
0 |
1554417 |
0 |
1554417 |
1554417 |
5.48 % |
14/02/2024 |
PAI LLC |
California |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
Palo Alto Investors LP |
California |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
Patrick Lee, MD |
USA |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
Patrick Lee, MD |
USA |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
Anthony Joonkyoo Yun, MD |
USA |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
Palo Alto Investors LP |
California |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
PAI LLC |
California |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
Anthony Joonkyoo Yun, MD |
USA |
0 |
2739379 |
0 |
2739379 |
2739379 |
9.66 % |
14/02/2024 |
The Vanguard Group |
Pennsylvania |
0 |
28382 |
1381668 |
40608 |
1422276 |
5.01 % |
13/02/2024 |
Millennium Group Management LLC |
Delaware |
0 |
381716 |
0 |
381716 |
381716 |
1.3 % |
25/01/2024 |
Israel A. Englander |
United States |
0 |
381716 |
0 |
381716 |
381716 |
1.3 % |
25/01/2024 |
Israel A. Englander |
United States |
0 |
381716 |
0 |
381716 |
381716 |
1.3 % |
25/01/2024 |
Millennium Group Management LLC |
Delaware |
0 |
381716 |
0 |
381716 |
381716 |
1.3 % |
25/01/2024 |
Millennium Management LLC |
Delaware |
0 |
381716 |
0 |
381716 |
381716 |
1.3 % |
25/01/2024 |
Millennium Management LLC |
Delaware |
0 |
381716 |
0 |
381716 |
381716 |
1.3 % |
25/01/2024 |
BlackRock, Inc. |
Delaware |
2575645 |
0 |
2661714 |
0 |
2661714 |
9.4 % |
24/01/2024 |
FINDELL CAPITAL MANAGEMENT LLC |
DELAWARE |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
FINN MANAGEMENT GP LLC |
DELAWARE |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
BRIAN A. FINN |
USA |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
FINDELL CAPITAL PARTNERS, LP |
DELAWARE |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
BRIAN A. FINN |
USA |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
FINN MANAGEMENT GP LLC |
DELAWARE |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
FINDELL CAPITAL MANAGEMENT LLC |
DELAWARE |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
FINDELL CAPITAL PARTNERS, LP |
DELAWARE |
1442000 |
0 |
1442000 |
0 |
1442000 |
5.1 % |
19/12/2023 |
Anthony Joonkyoo Yun, MD |
USA |
0 |
2484479 |
0 |
2484479 |
2484479 |
9.06 % |
14/02/2023 |
PAI LLC |
California |
0 |
2484479 |
0 |
2484479 |
2484479 |
9.06 % |
14/02/2023 |
Patrick Lee, MD |
USA |
0 |
2484479 |
0 |
2484479 |
2484479 |
9.06 % |
14/02/2023 |
Palo Alto Investors LP |
California |
0 |
2484479 |
0 |
2484479 |
2484479 |
9.06 % |
14/02/2023 |
The Vanguard Group |
Pennsylvania |
0 |
19675 |
1271864 |
28117 |
1299981 |
4.74 % |
09/02/2023 |
The Vanguard Group |
Pennsylvania |
0 |
19675 |
1271864 |
28117 |
1299981 |
4.74 % |
09/02/2023 |
Ruffer LLP |
London, United Kingdom |
520 |
0 |
520 |
0 |
520 |
0.0019 % |
02/02/2023 |
Millennium Group Management LLC |
|
|
|
|
|
1568549 |
5.7 % |
09/01/2023 |
Millennium Management LLC |
|
|
|
|
|
1568549 |
5.7 % |
09/01/2023 |
Israel A. Englander |
|
|
|
|
|
1568549 |
5.7 % |
09/01/2023 |
Millennium Management LLC |
|
|
|
|
|
1568549 |
5.7 % |
09/01/2023 |
Israel A. Englander |
|
|
|
|
|
1568549 |
5.7 % |
09/01/2023 |
Millennium Group Management LLC |
|
|
|
|
|
1568549 |
5.7 % |
09/01/2023 |
Millennium Group Management LLC |
|
|
|
|
|
1468152 |
5.4 % |
16/11/2022 |
Millennium Group Management LLC |
|
|
|
|
|
1468152 |
5.4 % |
16/11/2022 |
Millennium Management LLC |
|
|
|
|
|
1468152 |
5.4 % |
16/11/2022 |
Israel A. Englander |
|
|
|
|
|
1468152 |
5.4 % |
16/11/2022 |
Millennium Management LLC |
|
|
|
|
|
1468152 |
5.4 % |
16/11/2022 |
Israel A. Englander |
|
|
|
|
|
1468152 |
5.4 % |
16/11/2022 |
BlackRock, Inc. |
Delaware |
1860079 |
0 |
1938372 |
0 |
1938372 |
7.1 % |
07/10/2022 |
PAI LLC |
California |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
PAI LLC |
California |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
Palo Alto Investors LP |
California |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
Anthony Joonkyoo Yun, MD |
USA |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
Patrick Lee, MD |
USA |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
Anthony Joonkyoo Yun, MD |
USA |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
Palo Alto Investors LP |
California |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
Patrick Lee, MD |
USA |
0 |
1615570 |
0 |
1615570 |
1615570 |
6.12 % |
14/02/2022 |
The Vanguard Group |
Pennsylvania |
0 |
33677 |
1916308 |
50817 |
1967125 |
7.45 % |
09/02/2022 |
BlackRock, Inc. |
Delaware |
3895255 |
0 |
3954778 |
0 |
3954778 |
15 % |
28/01/2022 |
Abigail P. Johnson |
United States of America |
0 |
0 |
22 |
0 |
22 |
0 % |
10/01/2022 |
FMR LLC |
Delaware |
0 |
0 |
22 |
0 |
22 |
0 % |
10/01/2022 |
Abigail P. Johnson |
United States of America |
0 |
0 |
22 |
0 |
22 |
0 % |
10/01/2022 |
FMR LLC |
Delaware |
0 |
0 |
22 |
0 |
22 |
0 % |
10/01/2022 |
The Vanguard Group |
Pennsylvania |
0 |
58063 |
2160125 |
76874 |
2236999 |
8.64 % |
10/02/2021 |
BlackRock, Inc. |
Delaware |
3940030 |
0 |
3987273 |
0 |
3987273 |
15.4 % |
25/01/2021 |
OrbiMed Capital LLC |
Delaware |
0 |
977714 |
0 |
|
977714 |
4.23 % |
14/02/2020 |
OrbiMed Advisors LLC |
Delaware |
0 |
134200 |
0 |
134200 |
134200 |
0.58 % |
14/02/2020 |
OrbiMed Advisors LLC |
Delaware |
0 |
134200 |
0 |
134200 |
134200 |
0.58 % |
14/02/2020 |
OrbiMed Capital LLC |
Delaware |
0 |
977714 |
0 |
|
977714 |
4.23 % |
14/02/2020 |
Redmile Group, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2020 |
Jeremy C. Green |
United Kingdom |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2020 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
13/02/2020 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S James E. Flynn |
United States |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S James E. Flynn |
United States |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
13/02/2020 |
S Deerfield Partners, L.P. |
Delaware |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S Deerfield Partners, L.P. |
Delaware |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
204000 |
0 |
204000 |
204000 |
0.88 % |
13/02/2020 |
The Vanguard Group |
Pennsylvania |
46871 |
4586 |
1311536 |
49076 |
1360612 |
5.89 % |
12/02/2020 |
Abigail P. Johnson |
United States of America |
0 |
0 |
1686464 |
0 |
1686464 |
7.301 % |
07/02/2020 |
FMR LLC |
Delaware |
157190 |
0 |
1686464 |
0 |
1686464 |
7.301 % |
07/02/2020 |
BlackRock, Inc. |
Delaware |
3113112 |
0 |
3157828 |
0 |
3157828 |
13.7 % |
04/02/2020 |
J. Carlo Cannell |
USA |
0 |
392843 |
0 |
392843 |
392843 |
2 % |
14/02/2019 |
Cannell Capital LLC |
Wyoming, USA |
0 |
392843 |
0 |
392843 |
392843 |
2 % |
14/02/2019 |
Redmile Group, LLC |
Delaware |
0 |
1091395 |
0 |
1091395 |
1091395 |
5.6 % |
14/02/2019 |
Jeremy C. Green |
United Kingdom |
0 |
1091395 |
0 |
1091395 |
1091395 |
5.6 % |
14/02/2019 |
OrbiMed Advisors LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
12/02/2019 |
OrbiMed Capital LLC |
Delaware |
0 |
1100000 |
0 |
0 |
1100000 |
5.67 % |
12/02/2019 |
OrbiMed Advisors LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
12/02/2019 |
OrbiMed Capital LLC |
Delaware |
0 |
1100000 |
0 |
0 |
1100000 |
5.67 % |
12/02/2019 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
172806 |
0 |
172806 |
172806 |
0.89 % |
12/02/2019 |
S James E. Flynn |
United States |
0 |
1076402 |
0 |
1076402 |
1076402 |
5.55 % |
12/02/2019 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
1076402 |
0 |
1076402 |
1076402 |
5.55 % |
12/02/2019 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
1076402 |
0 |
1076402 |
1076402 |
5.55 % |
12/02/2019 |
S Deerfield Partners, L.P. |
Delaware |
0 |
903596 |
0 |
903596 |
903596 |
4.66 % |
12/02/2019 |
S James E. Flynn |
United States |
0 |
1076402 |
0 |
1076402 |
1076402 |
5.55 % |
12/02/2019 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
0 |
0 |
0 |
0 |
0 % |
12/02/2019 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
1076402 |
0 |
1076402 |
1076402 |
5.55 % |
12/02/2019 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
1076402 |
0 |
1076402 |
1076402 |
5.55 % |
12/02/2019 |
S Deerfield Partners, L.P. |
Delaware |
0 |
903596 |
0 |
903596 |
903596 |
4.66 % |
12/02/2019 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
172806 |
0 |
172806 |
172806 |
0.89 % |
12/02/2019 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
0 |
0 |
0 |
0 |
0 % |
12/02/2019 |
Wellington Group Holdings LLP |
Delaware |
0 |
767444 |
0 |
853798 |
853798 |
4.4 % |
12/02/2019 |
Wellington Group Holdings LLP |
Delaware |
0 |
767444 |
0 |
853798 |
853798 |
4.4 % |
12/02/2019 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
767444 |
0 |
853798 |
853798 |
4.4 % |
12/02/2019 |
Wellington Management Group LLP |
Massachusetts |
0 |
767444 |
0 |
853798 |
853798 |
4.4 % |
12/02/2019 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
767444 |
0 |
853798 |
853798 |
4.4 % |
12/02/2019 |
Wellington Management Group LLP |
Massachusetts |
0 |
767444 |
0 |
853798 |
853798 |
4.4 % |
12/02/2019 |
The Vanguard Group |
Pennsylvania |
18379 |
1678 |
1023358 |
17676 |
1041034 |
5.36 % |
11/02/2019 |
BlackRock, Inc. |
Delaware |
2525264 |
0 |
2565558 |
0 |
2565558 |
13.2 % |
28/01/2019 |
Cannell Capital LLC |
Wyoming, USA |
0 |
1091878 |
0 |
1091878 |
1091878 |
5.9 % |
15/02/2018 |
J. Carlo Cannell |
USA |
0 |
1091878 |
0 |
1091878 |
1091878 |
5.9 % |
15/02/2018 |
Cannell Capital LLC |
Wyoming, USA |
0 |
1091878 |
0 |
1091878 |
1091878 |
5.9 % |
15/02/2018 |
J. Carlo Cannell |
USA |
0 |
1091878 |
0 |
1091878 |
1091878 |
5.9 % |
15/02/2018 |
J. Carlo Cannell |
USA |
0 |
1091878 |
0 |
1091878 |
1091878 |
5.9 % |
14/02/2018 |
Cannell Capital LLC |
Wyoming, USA |
0 |
1091878 |
0 |
1091878 |
1091878 |
5.9 % |
14/02/2018 |
JEREMY C. GREEN |
UNITED KINGDOM |
0 |
1558914 |
0 |
1558914 |
1558914 |
8.37 % |
14/02/2018 |
Redmile Group, LLC |
DELAWARE |
0 |
1558914 |
0 |
1558914 |
1558914 |
8.37 % |
14/02/2018 |
S Deerfield Partners, L.P. |
Delaware |
0 |
552283 |
0 |
552283 |
552283 |
2.97 % |
14/02/2018 |
S James E. Flynn |
United States |
0 |
1013916 |
0 |
1013916 |
1013916 |
5.44 % |
14/02/2018 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
1013916 |
0 |
1013916 |
1013916 |
5.44 % |
14/02/2018 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
160310 |
0 |
160310 |
160310 |
0.86 % |
14/02/2018 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
1013916 |
0 |
1013916 |
1013916 |
5.44 % |
14/02/2018 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
160310 |
0 |
160310 |
160310 |
0.86 % |
14/02/2018 |
S James E. Flynn |
United States |
0 |
1013916 |
0 |
1013916 |
1013916 |
5.44 % |
14/02/2018 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
1013916 |
0 |
1013916 |
1013916 |
5.44 % |
14/02/2018 |
S Deerfield Partners, L.P. |
Delaware |
0 |
552283 |
0 |
552283 |
552283 |
2.97 % |
14/02/2018 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
1013916 |
0 |
1013916 |
1013916 |
5.44 % |
14/02/2018 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
301323 |
0 |
301323 |
301323 |
1.62 % |
14/02/2018 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
301323 |
0 |
301323 |
301323 |
1.62 % |
14/02/2018 |
OrbiMed Capital LLC |
Delaware |
0 |
991500 |
0 |
|
991500 |
5.32 % |
13/02/2018 |
OrbiMed Advisors LLC |
Delaware |
0 |
843200 |
0 |
843200 |
843200 |
4.53 % |
13/02/2018 |
OrbiMed Advisors LLC |
Delaware |
0 |
843200 |
0 |
843200 |
843200 |
4.53 % |
13/02/2018 |
OrbiMed Capital LLC |
Delaware |
0 |
991500 |
0 |
|
991500 |
5.32 % |
13/02/2018 |
The Vanguard Group |
Pennsylvania |
27475 |
|
951281 |
27475 |
978756 |
5.25 % |
08/02/2018 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
878971 |
0 |
971396 |
971396 |
5.22 % |
08/02/2018 |
Wellington Group Holdings LLP |
Delaware |
0 |
878971 |
0 |
971396 |
971396 |
5.22 % |
08/02/2018 |
Wellington Management Group LLP |
Massachusetts |
0 |
878971 |
0 |
971396 |
971396 |
5.22 % |
08/02/2018 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware For |
0 |
0 |
0 |
0 |
10 |
0 % |
02/02/2018 |
BlackRock, Inc. |
Delaware |
2095445 |
0 |
2117944 |
0 |
2117944 |
11.4 % |
23/01/2018 |
Cannell Capital LLC |
Wyoming, USA |
0 |
1357045 |
0 |
1357045 |
1357045 |
7.3 % |
23/10/2017 |
J. Carlo Cannell |
USA |
0 |
1357045 |
0 |
1357045 |
1357045 |
7.3 % |
23/10/2017 |
J. Carlo Cannell |
USA |
0 |
1357045 |
0 |
1357045 |
1357045 |
7.3 % |
23/10/2017 |
Cannell Capital LLC |
Wyoming, USA |
0 |
1357045 |
0 |
1357045 |
1357045 |
7.3 % |
23/10/2017 |
Deerfield Partners, L.P. |
Delaware |
0 |
587610 |
0 |
587610 |
587610 |
3.19 % |
10/05/2017 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
1518246 |
0 |
1518246 |
1518246 |
8.24 % |
10/05/2017 |
Deerfield Management Company, L.P. |
Delaware |
0 |
1518246 |
0 |
1518246 |
1518246 |
8.24 % |
10/05/2017 |
Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
203683 |
0 |
203683 |
203683 |
1.11 % |
10/05/2017 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
726953 |
0 |
726953 |
726953 |
3.94 % |
10/05/2017 |
James E. Flynn |
United States |
0 |
1518246 |
0 |
1518246 |
1518246 |
8.24 % |
10/05/2017 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
1518246 |
0 |
1518246 |
1518246 |
8.24 % |
10/05/2017 |
Deerfield Management Company, L.P. |
Delaware |
0 |
1518246 |
0 |
1518246 |
1518246 |
8.24 % |
10/05/2017 |
Deerfield Partners, L.P. |
Delaware |
0 |
587610 |
0 |
587610 |
587610 |
3.19 % |
10/05/2017 |
Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
203683 |
0 |
203683 |
203683 |
1.11 % |
10/05/2017 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
726953 |
0 |
726953 |
726953 |
3.94 % |
10/05/2017 |
James E. Flynn |
United States |
0 |
1518246 |
0 |
1518246 |
1518246 |
8.24 % |
10/05/2017 |
JEREMY C. GREEN |
UNITED STATES |
0 |
997621 |
0 |
997621 |
997621 |
5.44 % |
14/02/2017 |
Redmile Group, LLC |
DELAWARE |
0 |
997621 |
0 |
997621 |
997621 |
5.44 % |
14/02/2017 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
2640609 |
0 |
2640609 |
2640609 |
14.4 % |
14/02/2017 |
S Deerfield Partners, L.P. |
Delaware |
0 |
859141 |
0 |
859141 |
859141 |
4.68 % |
14/02/2017 |
S Deerfield Partners, L.P. |
Delaware |
0 |
859141 |
0 |
859141 |
859141 |
4.68 % |
14/02/2017 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1062874 |
0 |
1062874 |
1062874 |
5.79 % |
14/02/2017 |
S James E. Flynn |
United States |
0 |
2640609 |
0 |
2640609 |
2640609 |
14.4 % |
14/02/2017 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
2640609 |
0 |
2640609 |
2640609 |
14.4 % |
14/02/2017 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
718594 |
0 |
718594 |
718594 |
3.92 % |
14/02/2017 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
2640609 |
0 |
2640609 |
2640609 |
14.4 % |
14/02/2017 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1062874 |
0 |
1062874 |
1062874 |
5.79 % |
14/02/2017 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
2640609 |
0 |
2640609 |
2640609 |
14.4 % |
14/02/2017 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
718594 |
0 |
718594 |
718594 |
3.92 % |
14/02/2017 |
S James E. Flynn |
United States |
0 |
2640609 |
0 |
2640609 |
2640609 |
14.4 % |
14/02/2017 |
OrbiMed Advisors LLC |
Delaware |
0 |
836200 |
0 |
836200 |
836200 |
4.56 % |
13/02/2017 |
Samuel D. Isaly |
United States |
0 |
1820000 |
0 |
1820000 |
1820000 |
9.92 % |
13/02/2017 |
OrbiMed Capital LLC |
Delaware |
0 |
983800 |
0 |
0 |
983800 |
5.36 % |
13/02/2017 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware For |
935401 |
0 |
0 |
0 |
935401 |
5.09 % |
13/02/2017 |
Wellington Management Group LLP |
Massachusetts |
0 |
528622 |
0 |
1513953 |
1513953 |
8.25 % |
09/02/2017 |
Wellington Management Company LLP |
Delaware |
0 |
526969 |
0 |
1462370 |
1462370 |
7.97 % |
09/02/2017 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
528622 |
0 |
1513953 |
1513953 |
8.25 % |
09/02/2017 |
Wellington Group Holdings LLP |
Delaware |
0 |
528622 |
0 |
1513953 |
1513953 |
8.25 % |
09/02/2017 |
BlackRock, Inc. |
Delaware |
2004940 |
0 |
2035948 |
0 |
2035948 |
11.1 % |
12/01/2017 |
BlackRock, Inc. |
Delaware |
1787492 |
0 |
1825123 |
0 |
1825123 |
10 % |
09/08/2016 |
OrbiMed Advisors LLC |
Delaware |
0 |
600000 |
0 |
600000 |
600000 |
3.31 % |
16/02/2016 |
OrbiMed Advisors LLC |
Delaware |
0 |
600000 |
0 |
600000 |
600000 |
3.31 % |
16/02/2016 |
OrbiMed Capital LLC |
Delaware |
0 |
700000 |
0 |
0 |
700000 |
3.86 % |
16/02/2016 |
Samuel D. Isaly |
United States |
0 |
1300000 |
0 |
1300000 |
1300000 |
7.18 % |
16/02/2016 |
OrbiMed Capital LLC |
Delaware |
0 |
700000 |
0 |
0 |
700000 |
3.86 % |
16/02/2016 |
Samuel D. Isaly |
United States |
0 |
1300000 |
0 |
1300000 |
1300000 |
7.18 % |
16/02/2016 |
S Deerfield Mgmt, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.02 % |
16/02/2016 |
S Deerfield Management Company, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.02 % |
16/02/2016 |
S Deerfield Partners, L.P. |
Delaware |
0 |
859141 |
0 |
859141 |
859141 |
4.74 % |
16/02/2016 |
S Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
1342573 |
0 |
1342573 |
1342573 |
7.41 % |
16/02/2016 |
James E. Flynn |
United States |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.02 % |
16/02/2016 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1062874 |
0 |
1062874 |
1062874 |
5.87 % |
16/02/2016 |
Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
1342573 |
0 |
1342573 |
1342573 |
7.41 % |
16/02/2016 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.02 % |
16/02/2016 |
Deerfield Management Company, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.02 % |
16/02/2016 |
Deerfield Partners, L.P. |
Delaware |
0 |
859141 |
0 |
859141 |
859141 |
4.74 % |
16/02/2016 |
S Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1062874 |
0 |
1062874 |
1062874 |
5.87 % |
16/02/2016 |
S James E. Flynn |
United States |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.02 % |
16/02/2016 |
RS Investment Management Co. LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
11/02/2016 |
Wellington Group Holdings LLP |
Delaware |
0 |
734654 |
0 |
2182289 |
2182289 |
12.05 % |
11/02/2016 |
Wellington Management Group LLP |
Massachusetts |
0 |
734654 |
0 |
2182289 |
2182289 |
12.05 % |
11/02/2016 |
Wellington Group Holdings LLP |
Delaware |
0 |
734654 |
0 |
2182289 |
2182289 |
12.05 % |
11/02/2016 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
734654 |
0 |
2182289 |
2182289 |
12.05 % |
11/02/2016 |
Wellington Management Company LLP |
Delaware |
0 |
732961 |
0 |
2113366 |
2113366 |
11.66 % |
11/02/2016 |
Wellington Management Company LLP |
Delaware |
0 |
732961 |
0 |
2113366 |
2113366 |
11.66 % |
11/02/2016 |
Wellington Management Group LLP |
Massachusetts |
0 |
734654 |
0 |
2182289 |
2182289 |
12.05 % |
11/02/2016 |
Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
734654 |
0 |
2182289 |
2182289 |
12.05 % |
11/02/2016 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware For |
1380405 |
0 |
0 |
0 |
1380405 |
7.61 % |
09/02/2016 |
BlackRock, Inc. |
Delaware |
1667820 |
0 |
1700267 |
0 |
1700267 |
9.4 % |
26/01/2016 |
RS Investment Management Co. LLC |
Delaware |
721361 |
0 |
725740 |
0 |
725740 |
4.07 % |
10/04/2015 |
RS Investment Management Co. LLC |
Delaware |
721361 |
0 |
725740 |
0 |
725740 |
4.07 % |
10/04/2015 |
Gilder, Gagnon, Howe & Co. LLC |
New York |
0 |
0 |
0 |
90 |
90 |
0 % |
09/03/2015 |
Gilder, Gagnon, Howe & Co. LLC |
New York |
0 |
0 |
0 |
90 |
90 |
0 % |
09/03/2015 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1062874 |
0 |
1062874 |
1062874 |
5.97 % |
09/03/2015 |
Deerfield Management Company, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.32 % |
09/03/2015 |
Deerfield Partners, L.P. |
Delaware |
0 |
859141 |
0 |
859141 |
859141 |
4.82 % |
09/03/2015 |
Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
1342573 |
0 |
1342573 |
1342573 |
7.54 % |
09/03/2015 |
James E. Flynn |
United States |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.32 % |
09/03/2015 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.32 % |
09/03/2015 |
Deerfield Management Company, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.32 % |
09/03/2015 |
Deerfield Partners, L.P. |
Delaware |
0 |
859141 |
0 |
859141 |
859141 |
4.82 % |
09/03/2015 |
Deerfield Special Situations Fund, L.P. |
Delaware |
0 |
1342573 |
0 |
1342573 |
1342573 |
7.54 % |
09/03/2015 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1062874 |
0 |
1062874 |
1062874 |
5.97 % |
09/03/2015 |
James E. Flynn |
United States |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.32 % |
09/03/2015 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.32 % |
09/03/2015 |
RS Investment Management Co. LLC |
Delaware |
1865859 |
0 |
1876488 |
0 |
1876488 |
10.53 % |
12/02/2015 |
Wellington Management Group LLP |
Massachusetts |
0 |
847008 |
0 |
2308573 |
2308573 |
12.96 % |
12/02/2015 |
T. ROWE PRICE ASSOCIATES, INC. |
MARYLAND |
0 |
0 |
0 |
0 |
8800 |
0 % |
11/02/2015 |
Gilder, Gagnon, Howe & Co. LLC |
New York |
11637 |
0 |
11637 |
1094044 |
1105681 |
6.21 % |
10/02/2015 |
Integrated Assets II LLC |
|
|
|
|
|
193377 |
1.1 % |
06/02/2015 |
Integrated Core Strategies (US) LLC |
|
|
|
|
|
0 |
0 % |
06/02/2015 |
Millennium International Management GP LLC |
|
|
|
|
|
0 |
0 % |
06/02/2015 |
Millennium Management LLC |
|
|
|
|
|
193377 |
1.1 % |
06/02/2015 |
Millennium International Management LP |
|
|
|
|
|
0 |
0 % |
06/02/2015 |
Israel A. Englander |
|
|
|
|
|
193377 |
1.1 % |
06/02/2015 |
ICS Opportunities, Ltd. |
|
|
|
|
|
0 |
0 % |
06/02/2015 |
Integrated Assets, Ltd. |
|
|
|
|
|
0 |
0 % |
06/02/2015 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware For |
1380405 |
0 |
0 |
0 |
1380405 |
7.74 % |
06/02/2015 |
James E. Flynn |
United States |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.37 % |
20/01/2015 |
Deerfield Partners, L.P. |
Delaware |
0 |
1459685 |
0 |
1459685 |
1459685 |
8.21 % |
20/01/2015 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.37 % |
20/01/2015 |
Deerfield Management Company, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.37 % |
20/01/2015 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1804903 |
0 |
1804903 |
1804903 |
10.16 % |
20/01/2015 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.37 % |
20/01/2015 |
James E. Flynn |
United States |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.37 % |
20/01/2015 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1804903 |
0 |
1804903 |
1804903 |
10.16 % |
20/01/2015 |
Deerfield Partners, L.P. |
Delaware |
0 |
1459685 |
0 |
1459685 |
1459685 |
8.21 % |
20/01/2015 |
Deerfield Management Company, L.P. |
Delaware |
0 |
3264588 |
0 |
3264588 |
3264588 |
18.37 % |
20/01/2015 |
BlackRock, Inc. |
Delaware |
1575972 |
0 |
1619538 |
0 |
1619538 |
9.1 % |
15/01/2015 |
Fargo & Company |
Delaware |
824 |
610802 |
824 |
624870 |
625694 |
3.51 % |
12/01/2015 |
Integrated Core Strategies (US) LLC |
|
|
|
|
|
676310 |
3.8 % |
13/08/2014 |
Millennium International Management LP |
|
|
|
|
|
269559 |
1.5 % |
13/08/2014 |
Millennium International Management GP LLC |
|
|
|
|
|
269559 |
1.5 % |
13/08/2014 |
Israel A. Englander |
|
|
|
|
|
945869 |
5.3 % |
13/08/2014 |
Millennium Management LLC |
|
|
|
|
|
945869 |
5.3 % |
13/08/2014 |
ICS Opportunities, Ltd. |
|
|
|
|
|
265475 |
1.5 % |
13/08/2014 |
Integrated Assets, Ltd. |
|
|
|
|
|
4084 |
0 % |
13/08/2014 |
James E. Flynn |
United States |
0 |
2261457 |
0 |
2261457 |
2261457 |
12.73 % |
05/08/2014 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1250172 |
0 |
1250172 |
1250172 |
7.04 % |
05/08/2014 |
Deerfield Partners, L.P. |
Delaware |
0 |
1011285 |
0 |
1011285 |
1011285 |
5.69 % |
05/08/2014 |
James E. Flynn |
United States |
0 |
2261457 |
0 |
2261457 |
2261457 |
12.73 % |
05/08/2014 |
Deerfield Management Company, L.P. |
Delaware |
0 |
2261457 |
0 |
2261457 |
2261457 |
12.73 % |
05/08/2014 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
1250172 |
0 |
1250172 |
1250172 |
7.04 % |
05/08/2014 |
Deerfield Partners, L.P. |
Delaware |
0 |
1011285 |
0 |
1011285 |
1011285 |
5.69 % |
05/08/2014 |
Deerfield Management Company, L.P. |
Delaware |
0 |
2261457 |
0 |
2261457 |
2261457 |
12.73 % |
05/08/2014 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
2261457 |
0 |
2261457 |
2261457 |
12.73 % |
05/08/2014 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
2261457 |
0 |
2261457 |
2261457 |
12.73 % |
05/08/2014 |
RS Investment Management Co. LLC |
Delaware |
2075720 |
0 |
2084349 |
0 |
2084349 |
10.96 % |
10/07/2014 |
RS Investment Management Co. LLC |
Delaware |
2075720 |
0 |
2084349 |
0 |
2084349 |
10.96 % |
10/07/2014 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
726607 |
0 |
726607 |
726607 |
3.82 % |
15/05/2014 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
1314356 |
0 |
1314356 |
1314356 |
6.91 % |
15/05/2014 |
Deerfield Management Company, L.P. |
Delaware |
0 |
1314356 |
0 |
1314356 |
1314356 |
6.91 % |
15/05/2014 |
Deerfield Mgmt, L.P. |
Delaware |
0 |
1314356 |
0 |
1314356 |
1314356 |
6.91 % |
15/05/2014 |
Deerfield Partners, L.P. |
Delaware |
0 |
587749 |
0 |
587749 |
587749 |
3.09 % |
15/05/2014 |
Deerfield Management Company, L.P. |
Delaware |
0 |
1314356 |
0 |
1314356 |
1314356 |
6.91 % |
15/05/2014 |
Deerfield Partners, L.P. |
Delaware |
0 |
587749 |
0 |
587749 |
587749 |
3.09 % |
15/05/2014 |
Deerfield International Master Fund, L.P. |
British Virgin Islands |
0 |
726607 |
0 |
726607 |
726607 |
3.82 % |
15/05/2014 |
James E. Flynn |
United States |
0 |
1314356 |
0 |
1314356 |
1314356 |
6.91 % |
15/05/2014 |
James E. Flynn |
United States |
0 |
1314356 |
0 |
1314356 |
1314356 |
6.91 % |
15/05/2014 |
S Wellington Management Company, LLP |
Massachusetts |
0 |
925811 |
0 |
2561236 |
2561236 |
13.75 % |
14/02/2014 |
RS Investment Management Co. LLC |
Delaware |
1067960 |
|
1092996 |
|
1092996 |
5.87 % |
13/02/2014 |
The Vanguard Group |
Pennsylvania |
24609 |
|
655605 |
23209 |
678814 |
3.64 % |
12/02/2014 |
T. ROWE PRICE ASSOCIATES, INC. |
MARYLAND |
0 |
0 |
0 |
0 |
1050900 |
5.6 % |
10/02/2014 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware |
1538565 |
|
0 |
0 |
1538565 |
8.26 % |
04/02/2014 |
BlackRock, Inc. |
Delaware |
1630421 |
0 |
1685523 |
0 |
1685523 |
9.1 % |
29/01/2014 |
Fargo & Company |
Delaware |
0 |
1247260 |
0 |
1278577 |
1278577 |
6.87 % |
27/01/2014 |
RS Partners Fund |
Massachusetts |
0 |
588585 |
0 |
588585 |
588585 |
3.2 % |
08/11/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
1126331 |
0 |
1126331 |
1126331 |
6.12 % |
08/11/2013 |
RS Partners Fund |
Massachusetts |
0 |
588585 |
0 |
588585 |
588585 |
3.2 % |
08/11/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
1126331 |
0 |
1126331 |
1126331 |
6.12 % |
08/11/2013 |
RS Partners Fund |
Massachusetts |
0 |
1433925 |
0 |
1433925 |
1433925 |
7.1 % |
07/03/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
2855535 |
0 |
2895711 |
2895711 |
14.3 % |
07/03/2013 |
Guardian Investor Services LLC |
Delaware |
0 |
2855535 |
0 |
2895711 |
2895711 |
14.3 % |
07/03/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
2855535 |
0 |
2895711 |
2895711 |
14.3 % |
07/03/2013 |
Guardian Investor Services LLC |
Delaware |
0 |
2855535 |
0 |
2895711 |
2895711 |
14.3 % |
07/03/2013 |
RS Partners Fund |
Massachusetts |
0 |
1433925 |
0 |
1433925 |
1433925 |
7.1 % |
07/03/2013 |
The Guardian Life Insurance Company of America |
New York |
0 |
2855535 |
0 |
2895711 |
2895711 |
14.3 % |
07/03/2013 |
The Guardian Life Insurance Company of America |
New York |
0 |
2855535 |
0 |
2895711 |
2895711 |
14.3 % |
07/03/2013 |
The Guardian Life Insurance Company of America |
New York |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
22/02/2013 |
RS Partners Fund |
Massachusetts |
0 |
1301925 |
0 |
1301925 |
1301925 |
6.4 % |
22/02/2013 |
The Guardian Life Insurance Company of America |
New York |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
22/02/2013 |
Guardian Investor Services LLC |
Delaware |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
22/02/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
22/02/2013 |
Guardian Investor Services LLC |
Delaware |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
22/02/2013 |
RS Partners Fund |
Massachusetts |
0 |
1301925 |
0 |
1301925 |
1301925 |
6.4 % |
22/02/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
22/02/2013 |
RS Partners Fund |
Massachusetts |
0 |
1301925 |
0 |
1301925 |
1301925 |
6.4 % |
15/02/2013 |
The Guardian Life Insurance Company of America |
New York |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
15/02/2013 |
Guardian Investor Services LLC |
Delaware |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
15/02/2013 |
RS Investment Management Co. LLC |
Delaware |
0 |
2329188 |
0 |
2362864 |
2362864 |
11.7 % |
15/02/2013 |
The Vanguard Group |
Pennsylvania |
23981 |
|
1154438 |
22481 |
1176919 |
5.81 % |
11/02/2013 |
Gary L. Lauer |
U.S.A. |
1017684 |
0 |
1017684 |
0 |
1017684 |
4.98 % |
07/02/2013 |
BlackRock, Inc. |
Delaware |
1640219 |
0 |
1640219 |
0 |
1640219 |
8.1 % |
01/02/2013 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware |
1460025 |
|
0 |
0 |
1460025 |
7.2 % |
30/01/2013 |
Royce & Associates, LLC |
New York |
0 |
0 |
0 |
0 |
0 |
0 % |
06/12/2012 |
Royce & Associates, LLC |
New York |
0 |
0 |
0 |
0 |
0 |
0 % |
06/12/2012 |
Guardian Investor Services LLC |
Delaware |
0 |
3021748 |
0 |
3048436 |
3048436 |
15.2 % |
09/02/2012 |
The Guardian Life Insurance Company of America |
New York |
0 |
3021748 |
0 |
3048436 |
3048436 |
15.2 % |
09/02/2012 |
RS Partners Fund |
Massachusetts |
0 |
1799315 |
0 |
1799315 |
1799315 |
9 % |
09/02/2012 |
RS Investment Management Co. LLC |
Delaware |
0 |
3021748 |
0 |
3048436 |
3048436 |
15.2 % |
09/02/2012 |
THE VANGUARD GROUP, INC. |
Pennsylvania |
25715 |
|
1121381 |
25715 |
1147096 |
5.72 % |
09/02/2012 |
VANGUARD EXPLORER FUND VANGUARD EXPLORER FUND |
Delaware |
1055225 |
|
|
|
1055225 |
5.26 % |
26/01/2012 |
JPMorgan Chase & Co. |
Delaware |
537507 |
0 |
581761 |
0 |
581761 |
2.9 % |
11/01/2012 |
Royce & Associates, LLC |
New York |
|
|
1106500 |
|
1106500 |
5.52 % |
11/01/2012 |
Wellington Management Company, LLP |
Massachusetts |
0 |
1130180 |
0 |
2339480 |
2339480 |
10.93 % |
12/09/2011 |
Wellington Management Company, LLP |
Massachusetts |
0 |
1130180 |
0 |
2339480 |
2339480 |
10.93 % |
12/09/2011 |
Gary L. Lauer |
U.S.A. |
1275217 |
0 |
1275217 |
0 |
1275217 |
5.6 % |
14/02/2011 |
Ameriprise Financial, Inc. S.S. or |
Delaware |
0 |
1293870 |
0 |
1492685 |
1492685 |
6.73 % |
10/02/2011 |
Columbia ManagementInvestment Advisers, LLC S.S. or |
Minnesota |
0 |
1293870 |
0 |
1492685 |
1492685 |
6.73 % |
10/02/2011 |
Guardian Investor Services LLC |
Delaware |
0 |
2436096 |
0 |
2436096 |
2436096 |
11 % |
09/02/2011 |
RS Investment Management Co. LLC |
Delaware |
0 |
2436096 |
0 |
2436096 |
2436096 |
11 % |
09/02/2011 |
RS Partners Fund |
Massachusetts |
0 |
1471615 |
0 |
1471615 |
1471615 |
6.6 % |
09/02/2011 |
The Guardian Life Insurance Company of America |
New York |
0 |
2436096 |
0 |
2436096 |
2436096 |
11 % |
09/02/2011 |
BlackRock, Inc. |
Delaware |
1892542 |
0 |
1892542 |
0 |
1892542 |
8.53 % |
04/02/2011 |
Millennium Management LLC |
|
|
|
|
|
516745 |
2.3 % |
19/01/2011 |
Israel A. Englander |
|
|
|
|
|
516745 |
2.3 % |
19/01/2011 |
Millenco LLC |
|
|
|
|
|
48558 |
0.2 % |
19/01/2011 |
Integrated Core Strategies (US) LLC |
|
|
|
|
|
468187 |
2.1 % |
19/01/2011 |
JPMorgan Chase & Co. |
Delaware |
1118285 |
0 |
1203719 |
0 |
1203719 |
5.4 % |
19/01/2011 |
HealthCor Management, L.P. |
Delaware |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor Associates, LLC |
Delaware |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor Offshore, Ltd. |
Cayman Islands |
0 |
1294708 |
0 |
1294708 |
1294708 |
5.83 % |
12/11/2010 |
Joseph Healey |
United States |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
Arthur Cohen |
United States |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor Hybrid Offshore Master Fund, L.P. |
Cayman Islands |
0 |
317723 |
0 |
317723 |
317723 |
1.43 % |
12/11/2010 |
HealthCor Hybrid Offshore, Ltd. |
Cayman Islands |
0 |
317723 |
0 |
317723 |
317723 |
1.43 % |
12/11/2010 |
HealthCor Offshore GP, LLC |
Cayman Islands |
0 |
1294708 |
0 |
1294708 |
1294708 |
5.83 % |
12/11/2010 |
HealthCor L.P. |
Delaware |
0 |
637569 |
0 |
637569 |
637569 |
2.87 % |
12/11/2010 |
HealthCor Capital, L.P.. |
Delaware |
0 |
637569 |
0 |
637569 |
637569 |
2.87 % |
12/11/2010 |
HealthCor Group, LLC |
Delaware |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor Hybrid Offshore GP, LLC |
Cayman Islands |
0 |
317723 |
0 |
317723 |
317723 |
1.43 % |
12/11/2010 |
HealthCor Associates, LLC |
Delaware |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor Management, L.P. |
Delaware |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
Joseph Healey |
United States |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
Arthur Cohen |
United States |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor L.P. |
Delaware |
0 |
637569 |
0 |
637569 |
637569 |
2.87 % |
12/11/2010 |
HealthCor Capital, L.P.. |
Delaware |
0 |
637569 |
0 |
637569 |
637569 |
2.87 % |
12/11/2010 |
HealthCor Group, LLC |
Delaware |
0 |
2250000 |
0 |
2250000 |
2250000 |
10.14 % |
12/11/2010 |
HealthCor Hybrid Offshore GP, LLC |
Cayman Islands |
0 |
317723 |
0 |
317723 |
317723 |
1.43 % |
12/11/2010 |
HealthCor Hybrid Offshore Master Fund, L.P. |
Cayman Islands |
0 |
317723 |
0 |
317723 |
317723 |
1.43 % |
12/11/2010 |
HealthCor Hybrid Offshore, Ltd. |
Cayman Islands |
0 |
317723 |
0 |
317723 |
317723 |
1.43 % |
12/11/2010 |
HealthCor Offshore GP, LLC |
Cayman Islands |
0 |
1294708 |
0 |
1294708 |
1294708 |
5.83 % |
12/11/2010 |
HealthCor Offshore Master Fund, L.P. |
Cayman Islands |
0 |
1294708 |
0 |
1294708 |
1294708 |
5.83 % |
12/11/2010 |
HealthCor Offshore, Ltd. |
Cayman Islands |
0 |
1294708 |
0 |
1294708 |
1294708 |
5.83 % |
12/11/2010 |
HealthCor Offshore Master Fund, L.P. |
Cayman Islands |
0 |
1294708 |
0 |
1294708 |
1294708 |
5.83 % |
12/11/2010 |
The Guardian Life Insurance Company of America |
New York |
0 |
2364718 |
0 |
2364718 |
2364718 |
10 % |
08/09/2010 |
RS Partners Fund |
Massachusetts |
0 |
1534021 |
0 |
1534021 |
1534021 |
6.5 % |
08/09/2010 |
RS Investment Management Co. LLC |
Delaware |
0 |
2364718 |
0 |
2364718 |
2364718 |
10 % |
08/09/2010 |
Guardian Investor Services LLC |
Delaware |
0 |
2364718 |
0 |
2364718 |
2364718 |
10 % |
08/09/2010 |
The Guardian Life Insurance Company of America |
New York |
0 |
2364718 |
0 |
2364718 |
2364718 |
10 % |
08/09/2010 |
Guardian Investor Services LLC |
Delaware |
0 |
2364718 |
0 |
2364718 |
2364718 |
10 % |
08/09/2010 |
RS Investment Management Co. LLC |
Delaware |
0 |
2364718 |
0 |
2364718 |
2364718 |
10 % |
08/09/2010 |
RS Partners Fund |
Massachusetts |
0 |
1534021 |
0 |
1534021 |
1534021 |
6.5 % |
08/09/2010 |
Integrated Core Strategies |
Delaware |
0 |
935000 |
0 |
935000 |
935000 |
4 % |
20/04/2010 |
Israel A. Englander |
United States |
0 |
1220538 |
0 |
1220538 |
1220538 |
5.2 % |
20/04/2010 |
Millennium Management LLC |
Delaware |
0 |
1220538 |
0 |
1220538 |
1220538 |
5.2 % |
20/04/2010 |
Millenco LLC |
Delaware |
0 |
285538 |
0 |
285538 |
285538 |
1.2 % |
20/04/2010 |
Integrated Core Strategies |
Delaware |
0 |
935000 |
0 |
935000 |
935000 |
4 % |
20/04/2010 |
Israel A. Englander |
United States |
0 |
1220538 |
0 |
1220538 |
1220538 |
5.2 % |
20/04/2010 |
Millennium Management LLC |
Delaware |
0 |
1220538 |
0 |
1220538 |
1220538 |
5.2 % |
20/04/2010 |
Millenco LLC |
Delaware |
0 |
285538 |
0 |
285538 |
285538 |
1.2 % |
20/04/2010 |
JPMorgan Chase & Co. |
Delaware |
1215737 |
0 |
1312271 |
0 |
1312271 |
5.6 % |
21/01/2010 |
Arthur Cohen |
United States |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor, L.P. |
Delaware |
|
422424 |
0 |
422424 |
422424 |
1.81 % |
21/12/2009 |
HealthCor Hybrid Offshore GP, LLC |
Cayman Islands |
|
216940 |
0 |
216940 |
216940 |
0.93 % |
21/12/2009 |
Arthur Cohen |
United States |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor, L.P. |
Delaware |
|
422424 |
0 |
422424 |
422424 |
1.81 % |
21/12/2009 |
HealthCor Capital, L.P. |
Delaware |
|
422424 |
0 |
422424 |
422424 |
1.81 % |
21/12/2009 |
HealthCor Group, LLC |
Delaware |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Hybrid Offshore GP, LLC |
Cayman Islands |
|
216940 |
0 |
216940 |
216940 |
0.93 % |
21/12/2009 |
HealthCor Hybrid Offshore Master Fund, L.P. |
Cayman Islands |
|
216940 |
0 |
216940 |
216940 |
0.93 % |
21/12/2009 |
HealthCor Management, L.P. |
Delaware |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Offshore, Ltd. |
Cayman Islands |
|
960636 |
0 |
960636 |
960636 |
4.12 % |
21/12/2009 |
HealthCor Associates, LLC |
Delaware |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
Joseph Healey |
United States |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Group, LLC |
Delaware |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Capital, L.P. |
Delaware |
|
422424 |
0 |
422424 |
422424 |
1.81 % |
21/12/2009 |
HealthCor Offshore Master Fund, L.P. |
Cayman Islands |
|
960636 |
0 |
960636 |
960636 |
4.12 % |
21/12/2009 |
HealthCor Offshore GP, LLC |
Cayman Islands |
|
960636 |
0 |
960636 |
960636 |
4.12 % |
21/12/2009 |
HealthCor Hybrid Offshore, Ltd. |
Cayman Islands |
|
216940 |
0 |
216940 |
216940 |
0.93 % |
21/12/2009 |
Joseph Healey |
United States |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Hybrid Offshore Master Fund, L.P. |
Cayman Islands |
|
216940 |
0 |
216940 |
216940 |
0.93 % |
21/12/2009 |
HealthCor Associates, LLC |
Delaware |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Offshore, Ltd. |
Cayman Islands |
|
960636 |
0 |
960636 |
960636 |
4.12 % |
21/12/2009 |
HealthCor Offshore Master Fund, L.P. |
Cayman Islands |
|
960636 |
0 |
960636 |
960636 |
4.12 % |
21/12/2009 |
HealthCor Offshore GP, LLC |
Cayman Islands |
|
960636 |
0 |
960636 |
960636 |
4.12 % |
21/12/2009 |
HealthCor Management, L.P. |
Delaware |
|
1600000 |
0 |
1600000 |
1600000 |
6.85 % |
21/12/2009 |
HealthCor Hybrid Offshore, Ltd. |
Cayman Islands |
|
216940 |
0 |
216940 |
216940 |
0.93 % |
21/12/2009 |