| Oleg Nodelman |
United States of America |
0 |
6505890 |
0 |
10 |
6505890 |
9.9 % |
23/08/2024 |
| EcoR1 Capital, LLC |
Delaware |
0 |
6505890 |
0 |
10 |
6505890 |
9.9 % |
23/08/2024 |
| EcoR1 Capital Fund Qualified, L.P. |
Delaware |
0 |
6121338 |
0 |
10 |
6121338 |
9.3 % |
23/08/2024 |
| EcoR1 Capital Fund L.P. |
Delaware |
0 |
384552 |
0 |
10 |
384552 |
0.6 % |
23/08/2024 |
| EcoR1 Capital Fund Qualified, L.P. |
Delaware |
0 |
6128646 |
0 |
6128646 |
6128646 |
11 % |
07/06/2023 |
| Oleg Nodelman |
United States |
0 |
6505890 |
0 |
6505890 |
6505890 |
11 % |
07/06/2023 |
| contained in this form are not required to respond unless the form displays a currently valid OMB co |
Delaware |
0 |
6505890 |
0 |
6505890 |
6505890 |
11 % |
07/06/2023 |
| Oleg Nodelman |
United States |
0 |
3407246 |
0 |
3407246 |
3407246 |
11 % |
02/02/2022 |
| contained in this form are not required to respond unless the form displays a currently valid OMB co |
United States |
0 |
3407246 |
0 |
0 |
3407246 |
11 % |
02/02/2022 |
| 95-1411037 |
Delaware |
2923551 |
0 |
2923555 |
0 |
13 |
4.5 % |
10/05/2021 |
| 95-1411037 |
Delaware |
6987245 |
0 |
7091219 |
0 |
13 |
10.8 % |
10/02/2021 |
| 95-1411037 |
Delaware |
6206779 |
0 |
6311001 |
0 |
13 |
9.6 % |
10/02/2021 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Stichting Administratiekantoor Abchrys |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Stichting Administratiekantoor Penulata |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Van Herk Investments THI B.V. |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Van Herk Investments B.V. |
The Netherlands |
4893235 |
0 |
4893235 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Adrianus van Herk |
The Netherlands |
0 |
4893235 |
0 |
0 |
4893235 |
7.5 % |
29/01/2021 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Van Herk Investments THI B.V. |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Stichting Administratiekantoor Penulata |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Adrianus van Herk |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Stichting Administratiekantoor Abchrys |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
6071472 |
0 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Van Herk Investments B.V. |
The Netherlands |
6071472 |
0 |
6071472 |
0 |
6071472 |
9.4 % |
14/02/2020 |
| Wellington Management Group LLP |
Massachusetts |
0 |
2557289 |
0 |
0 |
2752374 |
4.26 % |
27/01/2020 |
| Wellington Group Holdings LLP |
Massachusetts |
0 |
2557289 |
0 |
0 |
2752374 |
4.26 % |
27/01/2020 |
| Wellington Investment Advisors Holdings LLP |
Massachusetts |
0 |
2557289 |
0 |
0 |
2752374 |
4.26 % |
27/01/2020 |
| Van Herk Investments B.V. |
The Netherlands |
5792737 |
0 |
5792737 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Stichting Administratiekantoor Abchrys |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Adrianus van Herk |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Stichting Administratiekantoor Penulata |
The Netherlands |
0 |
5792737 |
0 |
0 |
5792737 |
10.6 % |
17/07/2019 |
| Wellington Management Group LLP |
Massachusetts |
0 |
1948416 |
0 |
0 |
3427128 |
6.29 % |
12/02/2019 |
| Wellington Group Holdings LLP |
Delaware |
0 |
1948416 |
0 |
0 |
3427128 |
6.29 % |
12/02/2019 |
| Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
1948416 |
0 |
0 |
3427128 |
6.29 % |
12/02/2019 |
| Wellington Management Company LLP |
Delaware |
0 |
1930633 |
0 |
0 |
3337594 |
6.13 % |
12/02/2019 |
| Sands Capital Management, LLC |
Delaware, United States |
2056455 |
0 |
2894535 |
0 |
2894535 |
5.3 % |
10/01/2019 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Adrianus van Herk |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Stichting Administratiekantoor Abchrys |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Stichting Administratiekantoor Penulata |
The Netherlands |
0 |
5400228 |
0 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Van Herk Investments B.V. |
The Netherlands |
5400228 |
0 |
5400228 |
0 |
5400228 |
9.9 % |
23/11/2018 |
| Stichting Administratiekantoor Penulata |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| Adrianus van Herk |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| Van Herk Investments B.V. |
The Netherlands |
5133958 |
0 |
5133958 |
0 |
5133958 |
10 % |
12/06/2018 |
| Stichting Administratiekantoor Abchrys |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
5133958 |
0 |
0 |
5133958 |
10 % |
12/06/2018 |
| Gilead Therapeutics A1 Unlimited Company |
Ireland |
0 |
6760701 |
0 |
0 |
6760701 |
13.3 % |
08/03/2018 |
| Gilead Sciences, Inc. |
Ireland |
0 |
6760701 |
0 |
0 |
6760701 |
13.3 % |
08/03/2018 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Stichting Administratiekantoor Penulata |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Van Herk Investments B.V. |
The Netherlands |
4457147 |
0 |
4457147 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Stichting Administratiekantoor Abchrys |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Adrianus van Herk |
The Netherlands |
0 |
4457147 |
0 |
0 |
4457147 |
8.8 % |
15/02/2018 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
3943150 |
0 |
0 |
3943150 |
8.5 % |
15/02/2017 |
| Adrianus van Herk |
The Netherlands |
0 |
3943150 |
0 |
0 |
3943150 |
8.5 % |
15/02/2017 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
3943150 |
0 |
0 |
3943150 |
8.5 % |
15/02/2017 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
3943150 |
0 |
0 |
3943150 |
8.5 % |
15/02/2017 |
| Van Herk Investments B.V. |
The Netherlands |
3943150 |
0 |
3943150 |
0 |
3943150 |
8.5 % |
15/02/2017 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
3943150 |
0 |
0 |
3943150 |
8.5 % |
15/02/2017 |
| Wellington Investment Advisors Holdings LLP |
Massachusetts |
0 |
1199309 |
0 |
0 |
1333317 |
2.88 % |
09/02/2017 |
| Wellington Group Holdings LLP |
Massachusetts |
0 |
1199309 |
0 |
0 |
1333317 |
2.88 % |
09/02/2017 |
| Wellington Management Group LLP |
Massachusetts |
0 |
1199309 |
0 |
0 |
1333317 |
2.88 % |
09/02/2017 |
| J. Christopher Donahue |
Citizenship or place of Organization |
0 |
2127873 |
0 |
2127873 |
2127873 |
4.61 % |
10/08/2016 |
| Federated Investors, Inc. |
Citizenship or place of Organization |
2127873 |
0 |
2127873 |
0 |
2127873 |
4.61 % |
10/08/2016 |
| John F. Donahue |
Citizenship or place of Organization |
0 |
2127873 |
0 |
2127873 |
2127873 |
4.61 % |
10/08/2016 |
| Voting Shares Irrevocable Trust |
Citizenship or place of Organization |
2127873 |
0 |
2127873 |
0 |
2127873 |
4.61 % |
10/08/2016 |
| Rhodora J. Donahue |
Citizenship or place of Organization |
0 |
2127873 |
0 |
2127873 |
2127873 |
4.61 % |
10/08/2016 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
3423363 |
0 |
0 |
3423363 |
8.8 % |
16/02/2016 |
| Van Herk Investments B.V. |
The Netherlands |
3423363 |
0 |
3423363 |
0 |
3423363 |
8.8 % |
16/02/2016 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
3423363 |
0 |
0 |
3423363 |
8.8 % |
16/02/2016 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
3423363 |
0 |
0 |
3423363 |
8.8 % |
16/02/2016 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
3423363 |
0 |
0 |
3423363 |
8.8 % |
16/02/2016 |
| Adrianus van Herk |
The Netherlands |
0 |
3423363 |
0 |
0 |
3423363 |
8.8 % |
16/02/2016 |
| Wellington Management Group LLP |
Massachusetts |
0 |
2185242 |
0 |
0 |
2359857 |
6.04 % |
11/02/2016 |
| Wellington Group Holdings LLP |
Massachusetts |
0 |
2185242 |
0 |
0 |
2359857 |
6.04 % |
11/02/2016 |
| Wellington Investment Advisors Holdings LLP |
Massachusetts |
0 |
2185242 |
0 |
0 |
2359857 |
6.04 % |
11/02/2016 |
| Wellington Management Company LLP |
Massachusetts |
0 |
2092499 |
0 |
0 |
2226170 |
5.7 % |
11/02/2016 |
| J. Christopher Donahue |
Citizenship or place of Organization |
0 |
2528773 |
0 |
2528773 |
2528773 |
6.47 % |
11/02/2016 |
| John F. Donahue |
Citizenship or place of Organization |
0 |
2528773 |
0 |
2528773 |
2528773 |
6.47 % |
11/02/2016 |
| Rhodora J. Donahue |
Citizenship or place of Organization |
0 |
2528773 |
0 |
2528773 |
2528773 |
6.47 % |
11/02/2016 |
| Federated Investors, Inc. |
Citizenship or place of Organization |
2528773 |
0 |
2528773 |
0 |
2528773 |
6.47 % |
11/02/2016 |
| Voting Shares Irrevocable Trust |
Citizenship or place of Organization |
2528773 |
0 |
2528773 |
0 |
2528773 |
6.47 % |
11/02/2016 |
| Page 2 of 2 Pages |
State of Delaware |
6760701 |
0 |
6760701 |
0 |
6760701 |
12 % |
27/01/2016 |
| Van Herk Investments B.V. |
The Netherlands |
1997221 |
0 |
1997221 |
0 |
1997221 |
5.2 % |
18/06/2015 |
| Van Herk Private Equity Investments B.V. |
The Netherlands |
0 |
1997221 |
0 |
0 |
1997221 |
5.2 % |
18/06/2015 |
| A. van Herk Holding B.V. |
The Netherlands |
0 |
1997221 |
0 |
0 |
1997221 |
5.2 % |
18/06/2015 |
| Adrianus van Herk |
The Netherlands |
0 |
1997221 |
0 |
0 |
1997221 |
5.2 % |
18/06/2015 |
| Van Herk Management Services B.V. |
The Netherlands |
0 |
1997221 |
0 |
0 |
1997221 |
5.2 % |
18/06/2015 |
| Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V. |
The Netherlands |
0 |
1997221 |
0 |
0 |
1997221 |
5.2 % |
18/06/2015 |