The Vanguard Group |
Pennsylvania |
0 |
67784 |
6475124 |
221458 |
6696582 |
12.49 % |
13/02/2024 |
T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
1312632 |
0 |
3518326 |
0 |
3518326 |
6.6 % |
14/02/2023 |
T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
1312632 |
0 |
3518326 |
0 |
3518326 |
6.6 % |
14/02/2023 |
The Vanguard Group |
Pennsylvania For |
0 |
29894 |
5570014 |
65350 |
5635364 |
10.49 % |
09/02/2023 |
BlackRock, Inc. |
Delaware |
5029710 |
0 |
5424991 |
0 |
5424991 |
10.1 % |
09/02/2023 |
BlackRock, Inc. |
Delaware |
4983934 |
0 |
5367883 |
0 |
5367883 |
9.99 % |
26/01/2023 |
BlackRock, Inc. |
Delaware |
0 |
0 |
0 |
0 |
5367883 |
9.99 % |
20/01/2023 |
T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
1557185 |
0 |
3344626 |
0 |
3344626 |
6.1 % |
14/02/2022 |
T. ROWE PRICE ASSOCIATES, INC. |
Maryland |
1557185 |
0 |
3344626 |
0 |
3344626 |
6.1 % |
14/02/2022 |
The Vanguard Group |
Pennsylvania |
0 |
26083 |
5382103 |
71303 |
5453406 |
10.02 % |
10/02/2022 |
The Vanguard Group |
Pennsylvania For |
0 |
26083 |
5382103 |
71303 |
5453406 |
10.02 % |
10/02/2022 |
The Vanguard Group |
Pennsylvania For |
0 |
25774 |
5360720 |
70173 |
5430893 |
9.98 % |
10/02/2022 |
American Century Investment Management, Inc. |
Delaware |
1695845 |
0 |
1778638 |
0 |
1778638 |
3.27 % |
04/02/2022 |
American Century Capital Portfolios, Inc. |
Maryland |
1267915 |
0 |
1267915 |
0 |
1267915 |
2.33 % |
04/02/2022 |
American Century Capital Portfolios, Inc. |
Maryland |
1267915 |
0 |
1267915 |
0 |
1267915 |
2.33 % |
04/02/2022 |
American Century Investment Management, Inc. |
Delaware |
1695845 |
0 |
1778638 |
0 |
1778638 |
3.27 % |
04/02/2022 |
American Century Companies, Inc. |
Delaware |
1695845 |
0 |
1778638 |
0 |
1778638 |
3.27 % |
04/02/2022 |
Stowers Institute for Medical Research |
Delaware |
1695845 |
0 |
1778638 |
0 |
1778638 |
3.27 % |
04/02/2022 |
Stowers Institute for Medical Research |
Delaware |
1695845 |
0 |
1778638 |
0 |
1778638 |
3.27 % |
04/02/2022 |
American Century Companies, Inc. |
Delaware |
1695845 |
0 |
1778638 |
0 |
1778638 |
3.27 % |
04/02/2022 |
BlackRock, Inc. |
Delaware |
4388216 |
0 |
4600724 |
0 |
4600724 |
8.5 % |
31/01/2022 |
Capital World Investors |
Delaware |
1835000 |
0 |
1835000 |
0 |
1835000 |
3.4 % |
16/02/2021 |
Capital World Investors |
Delaware |
1835000 |
0 |
1835000 |
0 |
1835000 |
3.4 % |
16/02/2021 |
American Century Investment Management, Inc. |
Delaware |
3749513 |
0 |
3855532 |
0 |
3855532 |
7.11 % |
11/02/2021 |
American Century Companies, Inc. |
Delaware |
3749513 |
0 |
3855532 |
0 |
3855532 |
7.11 % |
11/02/2021 |
Stowers Institute for Medical Research |
Delaware |
3749513 |
0 |
3855532 |
0 |
3855532 |
7.11 % |
11/02/2021 |
American Century Capital Portfolios, Inc. |
Maryland |
2730748 |
0 |
2730748 |
0 |
2730748 |
5.03 % |
11/02/2021 |
American Century Investment Management, Inc. |
Delaware |
3749513 |
0 |
3855532 |
0 |
3855532 |
7.11 % |
11/02/2021 |
American Century Capital Portfolios, Inc. |
Maryland |
2730748 |
0 |
2730748 |
0 |
2730748 |
5.03 % |
11/02/2021 |
American Century Companies, Inc. |
Delaware |
3749513 |
0 |
3855532 |
0 |
3855532 |
7.11 % |
11/02/2021 |
Stowers Institute for Medical Research |
Delaware |
3749513 |
0 |
3855532 |
0 |
3855532 |
7.11 % |
11/02/2021 |
The Vanguard Group |
Pennsylvania |
0 |
37135 |
5475725 |
79281 |
5555006 |
10.24 % |
10/02/2021 |
BlackRock, Inc. |
Delaware |
4509788 |
0 |
4731442 |
0 |
4731442 |
8.7 % |
29/01/2021 |
The Vanguard Group |
Pennsylvania |
29739 |
8405 |
5781582 |
31119 |
5812701 |
10.68 % |
11/02/2020 |
Stowers Institute for Medical Research |
Delaware |
3537112 |
0 |
3647434 |
0 |
3647434 |
6.71 % |
11/02/2020 |
American Century Investment Management, Inc. |
Delaware |
3537112 |
0 |
3647434 |
0 |
3647434 |
6.71 % |
11/02/2020 |
American Century Companies, Inc. |
Delaware |
3537112 |
0 |
3647434 |
0 |
3647434 |
6.71 % |
11/02/2020 |
Stowers Institute for Medical Research |
Delaware |
3537112 |
0 |
3647434 |
0 |
3647434 |
6.71 % |
11/02/2020 |
American Century Investment Management, Inc. |
Delaware |
3537112 |
0 |
3647434 |
0 |
3647434 |
6.71 % |
11/02/2020 |
American Century Companies, Inc. |
Delaware |
3537112 |
0 |
3647434 |
0 |
3647434 |
6.71 % |
11/02/2020 |
BlackRock, Inc. |
Delaware |
6152052 |
0 |
6560936 |
0 |
6560936 |
12.1 % |
04/02/2020 |
BlackRock, Inc. |
Delaware |
5440832 |
0 |
5717421 |
0 |
5717421 |
10.5 % |
08/03/2019 |
American Century Companies, Inc. |
Delaware |
4404967 |
0 |
4561528 |
0 |
4561528 |
8.34 % |
11/02/2019 |
Stowers Institute for Medical Research |
Delaware |
4404967 |
0 |
4561528 |
0 |
4561528 |
8.34 % |
11/02/2019 |
American Century Investment Management, Inc. |
Delaware |
4404967 |
0 |
4561528 |
0 |
4561528 |
8.34 % |
11/02/2019 |
American Century Capital Portfolios, Inc. |
Maryland |
3222020 |
0 |
3222020 |
0 |
3222020 |
5.89 % |
11/02/2019 |
American Century Capital Portfolios, Inc. |
Maryland |
3222020 |
0 |
3222020 |
0 |
3222020 |
5.89 % |
11/02/2019 |
American Century Investment Management, Inc. |
Delaware |
4404967 |
0 |
4561528 |
0 |
4561528 |
8.34 % |
11/02/2019 |
American Century Companies, Inc. |
Delaware |
4404967 |
0 |
4561528 |
0 |
4561528 |
8.34 % |
11/02/2019 |
Stowers Institute for Medical Research |
Delaware |
4404967 |
0 |
4561528 |
0 |
4561528 |
8.34 % |
11/02/2019 |
BlackRock, Inc. |
Delaware |
5164305 |
0 |
5423903 |
0 |
5423903 |
9.9 % |
04/02/2019 |
The Vanguard Group |
Pennsylvania |
28992 |
7435 |
5494703 |
30930 |
5525633 |
10.1 % |
10/01/2019 |
The Vanguard Group |
Pennsylvania |
28992 |
7435 |
5494703 |
30930 |
5525633 |
10.1 % |
10/01/2019 |
The Vanguard Group |
Pennsylvania |
29739 |
6135 |
4638609 |
31717 |
4670326 |
8.53 % |
09/02/2018 |
BlackRock, Inc. |
Delaware |
4749581 |
0 |
5081849 |
0 |
5081849 |
9.3 % |
25/01/2018 |
The Vanguard Group |
Pennsylvania |
31225 |
5735 |
4220397 |
34149 |
4254546 |
7.68 % |
13/02/2017 |
BlackRock, Inc. |
Delaware |
3727868 |
0 |
3959337 |
0 |
3959337 |
7.2 % |
23/01/2017 |
BlackRock, Inc. |
Delaware |
3601894 |
0 |
3813750 |
0 |
3813750 |
7.5 % |
10/03/2016 |
Phillip Gross |
United States |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2016 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2016 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2016 |
Adage Capital Partners, L.P. |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2016 |
Robert Atchinson |
United States |
0 |
0 |
0 |
0 |
0 |
0 % |
16/02/2016 |
Capital World Investors |
Delaware |
3430000 |
0 |
3430000 |
0 |
3430000 |
5.9 % |
12/02/2016 |
The Vanguard Group |
Pennsylvania |
39456 |
2700 |
3584175 |
39156 |
3623331 |
6.26 % |
11/02/2016 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
17/02/2015 |
Adage Capital Partners, L.P. |
Delaware |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
17/02/2015 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
17/02/2015 |
Phillip Gross |
United States |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
17/02/2015 |
Robert Atchinson |
United States |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
17/02/2015 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
3838283 |
0 |
3838283 |
7.398 % |
13/02/2015 |
FMR LLC |
Delaware |
15015 |
0 |
3838283 |
0 |
3838283 |
7.398 % |
13/02/2015 |
Abigail P. Johnson |
United States of America |
0 |
0 |
3838283 |
0 |
3838283 |
7.398 % |
13/02/2015 |
BlackRock, Inc. |
Delaware |
3168804 |
0 |
3398428 |
0 |
3398428 |
6.6 % |
29/01/2015 |
FMR LLC |
Delaware |
9151 |
0 |
3249219 |
0 |
3249219 |
6.255 % |
10/10/2014 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
3249219 |
0 |
3249219 |
6.255 % |
10/10/2014 |
Abigail P. Johnson |
United States of America |
0 |
0 |
3249219 |
0 |
3249219 |
6.255 % |
10/10/2014 |
FMR LLC |
Delaware |
276829 |
0 |
5881009 |
0 |
5881009 |
11.322 % |
14/02/2014 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
5881009 |
0 |
5881009 |
11.322 % |
14/02/2014 |
Capital World Investors |
Delaware |
3430000 |
0 |
3430000 |
0 |
3430000 |
6.6 % |
13/02/2014 |
Adage Capital Partners, L.P. |
Delaware |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
05/02/2014 |
Adage Capital Partners GP, L.L.C. |
Delaware |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
05/02/2014 |
Phillip Gross |
United States |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
05/02/2014 |
Robert Atchinson |
United States |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
05/02/2014 |
Adage Capital Advisors, L.L.C. |
Delaware |
0 |
584532 |
0 |
584532 |
584532 |
8.16 % |
05/02/2014 |
BlackRock, Inc. |
Delaware |
3031272 |
0 |
3309533 |
0 |
3309533 |
6.4 % |
29/01/2014 |
FMR LLC |
Delaware |
288492 |
0 |
5686824 |
0 |
5686824 |
10.906 % |
10/09/2013 |
Edward C. Johnson 3d |
United States of America |
0 |
0 |
5686824 |
0 |
5686824 |
10.906 % |
10/09/2013 |
ZFIC, Inc. |
Wisconsin |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
Artisan Partners Funds, Inc. |
Wisconsin |
0 |
1907180 |
0 |
1907180 |
1907180 |
3.7 % |
08/02/2013 |
Carlene M. Ziegler |
U.S.A. |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
Andrew A. Ziegler |
U.S.A. |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
Artisan Investments GP LLC |
Delaware |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
Artisan Partners Limited Partnership |
Delaware |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
Artisan Investment Corporation |
Wisconsin |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
Artisan Partners Holdings LP |
Delaware |
0 |
2492232 |
0 |
2593032 |
2593032 |
5 % |
08/02/2013 |
BlackRock, Inc. |
Delaware |
5181032 |
0 |
5181032 |
0 |
5181032 |
9.94 % |
31/01/2013 |
BlackRock, Inc. |
Delaware |
5235331 |
0 |
5235331 |
0 |
5235331 |
10.03 % |
09/10/2012 |
BlackRock, Inc. |
Delaware |
4453690 |
0 |
4453690 |
0 |
4453690 |
8.6 % |
10/02/2012 |
Artisan Investments GP LLC |
Delaware |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
Carlene M. Ziegler |
U.S.A. |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
Artisan Funds, Inc. |
Wisconsin |
0 |
2635900 |
0 |
2635900 |
2635900 |
5 % |
11/02/2011 |
Artisan Partners Limited Partnership |
Delaware |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
Andrew A. Ziegler |
U.S.A. |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
ZFIC, Inc. |
Wisconsin |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
Artisan Investment Corporation |
Wisconsin |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
Artisan Partners Holdings LP |
Delaware |
0 |
3858551 |
0 |
3936851 |
3936851 |
7.5 % |
11/02/2011 |
BlackRock, Inc. |
Delaware |
4020257 |
0 |
4020257 |
0 |
4020257 |
7.61 % |
04/02/2011 |
Kenneth M. Garschina |
United States |
0 |
362337 |
0 |
362337 |
362337 |
5.1 % |
14/12/2010 |
Michael E. Martino |
United States |
0 |
362337 |
0 |
362337 |
362337 |
5.1 % |
14/12/2010 |
Mason Capital Management LLC, in its capacity as investment manager for certain investment funds and managed accounts |
Delaware |
362337 |
0 |
362337 |
0 |
362337 |
5.1 % |
14/12/2010 |