INSM

Insmed Incorporated INSM

Individual Beneficiary

Name of reporting person Citizenship or organization Sole voting power Shared voting power Sole dispositive power Shared dispositive power Amount beneficially owned Percent of class Accepted date
Darwin Global Management, Ltd. Jersey 0 9717822 0 0 9717822 5.7 % 03/09/2024
Darwin Global Master Fund, Ltd. Cayman Islands 0 9314373 0 0 9314373 5.4 % 03/09/2024
Dr. Abhishek Trehan United Kingdom 0 9717822 0 0 9717822 5.7 % 03/09/2024
85-4328500 Maryland 8905742 0 33228754 0 5850606 4.1 % 14/02/2024
85-4328500 Maryland 2598627 0 8374675 0 8374675 6.2 % 14/02/2023
STATE STREET CORPORATION BOSTON, MASSACHUSETTS 0 6602948 0 6886687 6886687 5.08 % 03/02/2023
52-0556948 Maryland 1768896 0 9247165 0 9247165 7.7 % 10/08/2022
PAI LLC California 0 0 0 6025706 6025706 5.09 % 14/02/2022
Anthony Joonkyoo Yun, MD USA 0 0 0 6025706 6025706 5.09 % 14/02/2022
Palo Alto Investors LP California 0 0 0 6025706 6025706 5.09 % 14/02/2022
Patrick Lee, MD USA 0 0 0 6025706 6025706 5.09 % 14/02/2022
52-0556948 Maryland 3407995 0 15321204 0 15321204 12.9 % 14/02/2022
Janus Henderson Group plc Jersey, Channel Islands 0 7881558 0 7881558 7881558 6.7 % 10/02/2022
The Vanguard Group - 23-1945930 Pennsylvania For 0 223603 10791972 328458 11120430 9.39 % 10/02/2022
(1) BlackRock, Inc. Delaware 9213553 0 9318130 0 9318130 7.9 % 08/02/2022
Abigail P. Johnson Delaware 0 0 5969955 0 5969955 5.793 % 12/04/2021
FMR LLC Delaware 209997 0 5969955 0 5969955 5.793 % 12/04/2021
Patrick Lee, MD USA 0 0 0 6105980 6105980 5.99 % 16/02/2021
PAI LLC California 0 0 0 6105980 6105980 5.99 % 16/02/2021
Palo Alto Investors LP California 0 0 0 6105980 6105980 5.99 % 16/02/2021
Anthony Joonkyoo Yun, MD USA 0 0 0 6105980 6105980 5.99 % 16/02/2021
Janus Henderson Group plc Jersey, Channel Islands 0 5822413 0 5822413 5822413 5.7 % 11/02/2021
52-0556948 Maryland 2151339 0 10372426 0 10372426 10.1 % 10/02/2021
52-0556948 Maryland 2066008 0 9652304 0 9652304 9.4 % 10/02/2021
The Vanguard Group - 23-1945930 Pennsylvania 0 234946 9046541 316586 9363127 9.19 % 10/02/2021
FMR LLC Delaware 397297 0 12088544 0 12088544 11.866 % 08/02/2021
(1) BlackRock, Inc. Delaware 8103929 0 8241967 0 8241967 8.1 % 29/01/2021
52-0556948 Maryland 1353471 0 6530775 0 6530775 7.3 % 14/02/2020
The Vanguard Group - 23-1945930 Pennsylvania 185819 14985 7985282 190794 8176076 9.15 % 12/02/2020
FMR LLC Delaware 421846 0 13401528 0 13401528 14.999 % 07/02/2020
(1) BlackRock, Inc. Delaware 7225867 0 7456517 0 7456517 8.3 % 05/02/2020
PAI LLC California 0 7653617 0 7653617 7653617 9.93 % 14/02/2019
Anthony Joonkyoo Yun, MD U.S.A. 0 7653617 0 7653617 7653617 9.93 % 14/02/2019
Palo Alto Healthcare Master Fund II, L.P. Cayman Islands 0 4333318 0 4333318 4333318 5.62 % 14/02/2019
Patrick Lee, MD U.S.A. 0 7653617 0 7653617 7653617 9.93 % 14/02/2019
Palo Alto Investors LP California 0 7653617 0 7653617 7653617 9.93 % 14/02/2019
52-0556948 Maryland 1459277 0 8676398 0 8676398 11.2 % 14/02/2019
FMR LLC Delaware 414147 0 11563534 0 11563534 14.999 % 13/02/2019
(1) BlackRock, Inc. Delaware 7234641 0 7451397 0 7451397 9.7 % 04/02/2019
52-0556948 Maryland 1500673 0 8950794 0 8950794 11.6 % 13/11/2018
Patrick Lee, MD California 0 6718495 0 6718495 6718495 8.77 % 14/02/2018
52-0556948 Maryland 1890016 0 13028622 0 13028622 17 % 14/02/2018
OrbiMed Advisors LLC Delaware 0 859700 0 0 859700 1.12 % 13/02/2018
OrbiMed Capital LLC Delaware 0 637091 0 0 637091 0.83 % 13/02/2018
(1) BlackRock, Inc. Delaware 7668742 0 7830604 0 7830604 10.2 % 19/01/2018
(1) BlackRock, Inc. Delaware 7736857 0 8464327 0 8464327 11.1 % 09/11/2017
(1) BlackRock, Inc. Delaware 4441420 0 4570668 0 4570668 7.4 % 25/01/2017
Patrick Lee, MD U.S.A. 0 5446516 0 5446516 5446516 8.8 % 12/01/2017
Patrick Lee, MD U.S.A. 0 4790800 0 4790800 4790800 7.75 % 16/02/2016
Point72 Asset Management, L.P. Delaware 0 0 0 0 0 0 % 16/02/2016
Point72 Capital Advisors, Inc. Delaware 0 0 0 0 0 0 % 16/02/2016
Cubist Systematic Strategies, LLC Delaware 0 10365 0 0 10365 4 % 16/02/2016
Steven A. Cohen United States 0 10365 0 0 10365 4 % 16/02/2016
NAME OF REPORTING Delaware 0 1375200 0 1375200 2094700 3.39 % 12/02/2016
NAME OF REPORTING Delaware 0 1375200 0 1375200 3469900 5.61 % 12/02/2016
NAME OF REPORTING Delaware 0 1375200 0 1375200 1375200 2.23 % 12/02/2016
(1) BlackRock, Inc. Delaware 3957384 0 4091461 0 4091461 6.6 % 26/01/2016
Anthony Joonkyoo Yun, MD U.S.A. 0 4625648 0 4625648 4625648 9.31 % 17/02/2015
Palo Alto Investors, LLC California 0 4625648 0 4625648 4625648 9.31 % 17/02/2015
Patrick Lee, MD U.S.A. 0 4625648 0 4625648 4625648 9.31 % 17/02/2015
Point72 Asset Management, L.P. Delaware 0 2840830 0 0 2840830 5.7 % 17/02/2015
Steven A. Cohen United States 0 2840907 0 0 2840907 5.7 % 17/02/2015
EverPoint Asset Management, LLC Delaware 0 0 0 0 0 0 % 17/02/2015
Point72 Capital Advisors, Inc. Delaware 0 2840830 0 0 2840830 5.7 % 17/02/2015
Cubist Systematic Strategies, LLC Delaware 0 77 0 0 77 4 % 17/02/2015
Deerfield Partners, L.P. Delaware 0 1001675 0 0 1001675 2.02 % 17/02/2015
Deerfield International Master Fund, L.P. British Virgin Islands 0 1239956 0 0 1239956 2.5 % 17/02/2015
Deerfield Special Situations Fund, L.P. Delaware 0 0 0 0 0 0 % 17/02/2015
Deerfield Mgmt, L.P. Delaware 0 2241631 0 0 2241631 4.51 % 17/02/2015
Deerfield Management Company, L.P. Delaware 0 2241631 0 0 2241631 4.51 % 17/02/2015
James E. Flynn United States 0 2241631 0 0 2241631 4.51 % 17/02/2015
Deerfield Special Situations International Master Fund, L.P. British Virgin Islands 0 0 0 0 0 0 % 17/02/2015
Quaker BioVentures Capital II, L.P. Delaware 0 1975251 0 0 1975251 4 % 13/02/2015
Quaker BioVentures Capital II, LLC Delaware 0 1975251 0 0 1975251 4 % 13/02/2015
Quaker BioVentures II, L.P. Delaware 0 1975251 0 0 1975251 4 % 13/02/2015
FMR LLC United States of America 0 0 7449749 0 7449749 14.999 % 13/02/2015
(1) BlackRock, Inc. Delaware 3394918 0 3494507 0 3494507 7 % 29/01/2015
Millennium International Management LP Cayman Islands 0 638364 0 638364 638364 1.3 % 15/01/2015
Millennium International Management GP LLC Cayman Islands 0 638364 0 638364 638364 1.3 % 15/01/2015
Integrated Core Strategies (US) LLC Cayman Islands 0 438616 0 438616 438616 0.9 % 15/01/2015
Israel A. Englander Cayman Islands 0 1076980 0 1076980 1076980 2.2 % 15/01/2015
Integrated Assets, Ltd. Cayman Islands 0 98624 0 98624 98624 0.2 % 15/01/2015
ICS Opportunities, Ltd. Cayman Islands 0 539740 0 539740 539740 1.1 % 15/01/2015
Millennium Management LLC Cayman Islands 0 1076980 0 1076980 1076980 2.2 % 15/01/2015
Steven A. Cohen United States 0 2109014 0 0 2109014 5.4 % 11/08/2014
Point72 Capital Advisors, Inc. Delaware 0 2045392 0 0 2045392 5.2 % 11/08/2014
Point72 Asset Management, L.P. Delaware 0 2045392 0 0 2045392 5.2 % 11/08/2014
EverPoint Asset Management, LLC Delaware 0 50000 0 0 50000 0.1 % 11/08/2014
Cubist Systematic Strategies, LLC Delaware 0 13622 0 0 13622 4 % 11/08/2014
Point72 Capital Advisors, Inc. Delaware 0 2045392 0 0 2045392 5.2 % 31/07/2014
Steven A. Cohen United States 0 2109014 0 0 2109014 5.4 % 31/07/2014
Point72 Asset Management, L.P. Delaware 0 2045392 0 0 2045392 5.2 % 31/07/2014
Cubist Systematic Strategies, LLC Delaware 0 13622 0 0 13622 4 % 31/07/2014
EverPoint Asset Management, LLC Delaware 0 50000 0 0 50000 0.1 % 31/07/2014
James E. Flynn United States 0 3043026 0 0 3043026 7.75 % 10/04/2014
Deerfield Special Situations International Master Fund, L.P. British Virgin Islands 0 148564 0 0 148564 0.38 % 10/04/2014
Deerfield Partners, L.P. Delaware 0 1205534 0 0 1205534 3.07 % 10/04/2014
Deerfield Special Situations Fund, L.P. Delaware 0 183052 0 0 183052 0.47 % 10/04/2014
Deerfield Management Company, L.P. Delaware 0 3043026 0 0 3043026 7.75 % 10/04/2014
Deerfield Mgmt, L.P. Delaware 0 3043026 0 0 3043026 7.75 % 10/04/2014
Deerfield International Master Fund, L.P. British Virgin Islands 0 1505876 0 0 1505876 3.84 % 10/04/2014
RA Capital Healthcare Fund, L.P. Massachusetts 0 0 0 0 0 0 % 14/02/2014
Peter Kolchinsky Massachusetts 0 0 0 0 0 0 % 14/02/2014
RA Capital Management, LLC Massachusetts 0 0 0 0 0 0 % 14/02/2014
13G Delaware, United States of America 0 1069940 0 1069940 1069940 2.7 % 10/02/2014
13G Delaware, United States of America 0 1069940 0 1069940 1069940 2.7 % 10/02/2014
Millennium Management LLC Delaware 0 2025437 0 2025437 2025437 5.2 % 31/01/2014
Integrated Core Strategies (US) LLC Delaware 0 1419763 0 1419763 1419763 3.6 % 31/01/2014
ICS Opportunities, Ltd. Delaware 0 590229 0 590229 590229 1.5 % 31/01/2014
Integrated Assets, Ltd. Delaware 0 15445 0 15445 15445 0 % 31/01/2014
Israel A. Englander Delaware 0 2025437 0 2025437 2025437 5.2 % 31/01/2014
Millennium International Management LP Delaware 0 605674 0 605674 605674 1.5 % 31/01/2014
Millennium International Management GP LLC Delaware 0 605674 0 605674 605674 1.5 % 31/01/2014
(1) BlackRock, Inc. Delaware 2047453 0 2122048 0 2122048 5.4 % 29/01/2014
FMR LLC Delaware 29442 0 5866478 0 5866478 15 % 10/01/2014
FMR LLC Delaware 344675 0 3798566 0 3798566 9.756 % 12/08/2013
Edward C. Johnson 3d United States of America 0 0 3798566 0 3798566 9.756 % 12/08/2013
Edward C. Johnson 3d Delaware 0 0 4700346 0 4700346 14.992 % 11/03/2013
FMR LLC Delaware 1893146 0 4700346 0 4700346 14.992 % 11/03/2013
RA Capital Management, LLC United States 2433319 0 2433319 0 2433319 7.8 % 14/02/2013
FMR LLC Delaware 11394 0 2818594 0 2818594 8.99 % 14/02/2013
Edward C. Johnson 3d United States of America 0 0 2818594 0 2818594 8.99 % 14/02/2013
Quaker BioVentures Capital II, L.P. Delaware 0 2927094 0 0 2927094 9.3 % 14/02/2013
Quaker BioVentures II, L.P. Delaware 0 2927094 0 0 2927094 9.3 % 14/02/2013
Quaker BioVentures Capital II, LLC Delaware 0 2927094 0 0 2927094 9.3 % 14/02/2013
ACM Capital Partners, LLC Delaware 0 1541469 0 1541469 1541469 4.92 % 06/12/2012
Ayer Capital Partners Master Fund, L.P. Delaware 0 1423979 0 1423979 1423979 4.54 % 06/12/2012
Jay Venkatesan Delaware 0 1541469 0 1541469 1541469 4.92 % 06/12/2012
Ayer Capital Partners, LLC Delaware 0 1423979 0 1423979 1423979 4.54 % 06/12/2012
Ayer Capital Management, LP Delaware 0 1541469 0 1541469 1541469 4.92 % 06/12/2012
Edward C. Johnson 3d Delaware 0 0 4000652 0 4000652 12.76 % 13/11/2012
FMR LLC Delaware 1881752 0 4000652 0 4000652 12.76 % 13/11/2012
Ayer Capital Management, LP USA 0 3116100 0 3116100 3116100 9.99 % 03/10/2012
Ayer Capital Partners Master Fund, L.P. USA 0 2878384 0 2878384 2878384 9.23 % 03/10/2012
Ayer Capital Partners, LLC USA 0 2878384 0 2878384 2878384 9.23 % 03/10/2012
Jay Venkatesan USA 0 3116100 0 3116100 3116100 9.99 % 03/10/2012
ACM Capital Partners, LLC USA 0 3116100 0 3116100 3116100 9.99 % 03/10/2012
Peter Kolchinsky Citizenship or Place of Organization 2459039 0 2459039 0 2459039 7.9 % 03/10/2012
RA Capital Healthcare Fund, L.P. Citizenship or Place of Organization 1484029 0 1484029 0 1484029 4.8 % 03/10/2012
RA Capital Management, LLC Massachusetts 2459039 0 2459039 0 2459039 7.9 % 03/10/2012
(1) BlackRock, Inc. Delaware 412386 0 412386 0 412386 1.66 % 10/07/2012
Quaker BioVentures Capital II, L.P. Delaware 0 2189994 0 0 2189994 8.82 % 14/02/2012
Quaker BioVentures II, L.P. Delaware 0 2189994 0 0 2189994 8.82 % 14/02/2012
Quaker BioVentures Capital II, LLC Delaware 5469 2189994 5469 0 2195463 8.84 % 14/02/2012
Edward C. Johnson 3d United States of America 0 0 1881752 0 1881752 7.578 % 14/02/2012
FMR LLC Delaware 1881752 0 1881752 0 1881752 7.578 % 14/02/2012
(1) BlackRock, Inc. Delaware 1328167 0 1328167 0 1328167 5.35 % 09/02/2012
Quaker BioVentures Capital II, L.P. Delaware 0 1861494 0 0 1861494 8.07 % 11/03/2011
Quaker BioVentures II, L.P. Delaware 0 1861494 0 0 1861494 8.07 % 11/03/2011
Quaker BioVentures Capital II, LLC Delaware 0 1861494 0 0 1861494 8.07 % 11/03/2011
FMR LLC Delaware 1599487 0 1599487 0 1599487 6.935 % 10/03/2011
Edward C. Johnson 3d Delaware 0 0 1599487 0 1599487 6.935 % 10/03/2011
Prospect Venture Partners III, L.P. Delaware, United States of America 0 0 0 1604940 1604940 7 % 08/03/2011
Prospect Management Co. III, L.L.C. Delaware, United States of America 0 0 0 1604940 1604940 7 % 08/03/2011
C. TANG STATES 0 600537 0 0 600537 0.5 % 14/02/2008
CAPITAL MANAGEMENT, LLC DELAWARE 0 600537 0 0 600537 0.5 % 14/02/2008
CAPITAL PARTNERS, LP DELAWARE 0 600537 0 0 600537 0.5 % 14/02/2008
SAGAMORE HILL MANAGERS LLC DELAWARE 3549505 0 3549505 0 3549505 6.18 % 14/02/2006
STEVEN H. BLOOM UNITED STATES 3549505 0 3549505 0 3549505 6.18 % 14/02/2006
SAGAMORE HILL CAPITAL MANAGEMENT L.P. DELAWARE 3549505 0 3549505 0 3549505 6.18 % 14/02/2006
SAGAMORE HILL MANAGERS LLC DELAWARE 2992279 0 2992279 0 2972279 6.24 % 24/03/2005
STEVEN H. BLOOM UNITED STATES 2992279 0 2992279 0 2972279 6.24 % 24/03/2005
SAGAMORE HILL CAPITAL MANAGEMENT L.P. DELAWARE 2992279 0 2992279 0 2972279 6.24 % 24/03/2005
(: United States 0 3590734 0 0 3590734 7.4 % 23/03/2005
(: Delaware 0 3590734 0 0 3590734 7.4 % 23/03/2005
(: Delaware 0 3590734 0 0 3590734 7.4 % 23/03/2005
N.A. British Virgin Islands 0 0 0 0 1291560 3.94 % 16/02/2001
RS Investment Management, L.P. California 0 1805700 0 1805700 1805700 5.5 % 15/02/2001
RS Investment Management Co. LLC Delaware 0 1805700 0 1805700 1805700 5.5 % 15/02/2001

Senat trading

Bureau Date de la transaction Date de réception Type Amount Commentaire

Senat Divulgation

Représentant Date de la transaction Date de divulgation Type Amount District
Gilbert Cisneros 2025-10-03 2025-11-19 Sale $1,001 - $15,000 CA31
Gilbert Cisneros 2025-09-22 2025-10-13 Sale $1,001 - $15,000 CA31
Gilbert Cisneros 2025-08-08 2025-09-12 Sale (Partial) $1,001 - $15,000 CA31
Gilbert Cisneros 2025-07-07 2025-08-15 Sale $1,001 - $15,000 CA31
Josh Gottheimer 2025-06-16 2025-07-17 Purchase $1,001 - $15,000 NJ05
Josh Gottheimer 2025-04-09 2025-05-14 Sale (Partial) $1,001 - $15,000 NJ05
Josh Gottheimer 2024-06-21 2024-07-09 Sale $1,001 - $15,000 NJ05
Josh Gottheimer 2024-05-28 2024-06-08 Sale $1,001 - $15,000 NJ05
Josh Gottheimer 2022-12-06 2023-01-13 Purchase $1,001 - $15,000 NJ05