| JPMORGAN CHASE & CO.13-2624428 |
Delaware |
4943665 |
0 |
5287819 |
39 |
5296395 |
5 % |
10/10/2024 |
| Wellington Management Group LLP |
Massachusetts |
0 |
5152705 |
0 |
0 |
5409685 |
5.71 % |
06/02/2023 |
| Wellington Group Holdings LLP |
Delaware |
0 |
5152705 |
0 |
0 |
5409685 |
5.71 % |
06/02/2023 |
| Wellington Management Company LLP |
Delaware |
0 |
5121657 |
0 |
0 |
5260610 |
5.55 % |
06/02/2023 |
| Wellington Investment Advisors Holdings LLP |
Delaware |
0 |
5152705 |
0 |
0 |
5409685 |
5.71 % |
06/02/2023 |
| Wasatch Advisors, Inc. 87-0319391 |
|
8235768 |
0 |
8235768 |
0 |
8235768 |
10.1 % |
10/02/2022 |
| (1) BlackRock, Inc. |
Delaware |
5640630 |
0 |
5721766 |
0 |
5721766 |
7 % |
03/02/2022 |
| BB Biotech AG |
|
0 |
3538419 |
0 |
3538419 |
3538419 |
4.4 % |
12/02/2021 |
| Biotech Target N.V. |
|
0 |
3538419 |
0 |
3538419 |
3538419 |
4.4 % |
12/02/2021 |
| The Vanguard Group - 23-1945930 |
Pennsylvania |
0 |
100311 |
6324408 |
156936 |
6481344 |
8.09 % |
10/02/2021 |
| Wasatch Advisors, Inc. 87-0319391 |
|
6333900 |
0 |
6333900 |
0 |
6333900 |
7.9 % |
09/02/2021 |
| Biotech Target N.V. |
Switzerland |
0 |
3458419 |
0 |
3458419 |
3458419 |
5.3 % |
06/02/2020 |
| BB Biotech AG |
Switzerland |
0 |
3458419 |
0 |
3458419 |
3458419 |
5.3 % |
06/02/2020 |
| (1) BlackRock, Inc. |
Delaware |
3897813 |
0 |
4004666 |
0 |
4004666 |
7.3 % |
04/02/2019 |
| The Sosland Foundation |
United States of America |
552548 |
0 |
552548 |
0 |
552548 |
1 % |
01/02/2018 |
| The Sosland Family Trust B Partnership |
United States of America |
1558554 |
0 |
1558554 |
0 |
1558554 |
2.9 % |
01/02/2018 |
| David N. Sosland Trust A |
United States of America |
527287 |
0 |
527287 |
0 |
527287 |
1 % |
01/02/2018 |
| Morton I. Sosland |
United States of America |
2638389 |
0 |
2638389 |
0 |
2638389 |
4.8 % |
01/02/2018 |
| (1) BlackRock, Inc. |
Delaware |
3926039 |
0 |
4002920 |
0 |
4002920 |
7.3 % |
25/01/2018 |
| 2. |
Switzerland |
0 |
2200000 |
0 |
2200000 |
2200000 |
5.1 % |
23/08/2017 |
| 10. |
Switzerland |
0 |
2200000 |
0 |
2200000 |
2200000 |
5.1 % |
23/08/2017 |
| (1) BlackRock, Inc. |
Delaware |
3471670 |
0 |
3528846 |
0 |
3528846 |
8.2 % |
26/01/2016 |
| (1) BlackRock, Inc. |
Delaware |
2149225 |
0 |
0 |
2182868 |
2182868 |
7.4 % |
10/04/2015 |
| Morton I. Sosland |
United States of America |
3388389 |
0 |
3388389 |
0 |
3388389 |
15.3 % |
09/09/2013 |
| The Sosland Foundation |
United States of America |
732548 |
0 |
732548 |
0 |
732548 |
3.3 % |
09/09/2013 |
| Sosland Family Trust B Partnership |
United States of America |
1948554 |
0 |
1948554 |
0 |
1948554 |
8.8 % |
09/09/2013 |
| David N. Sosland Trust A |
United States of America |
707287 |
0 |
707287 |
0 |
707287 |
3.2 % |
09/09/2013 |