NanoString Technologies, Inc. NSTG
Trading inactive
| Name of reporting person | Citizenship or organization | Sole voting power | Shared voting power | Sole dispositive power | Shared dispositive power | Amount beneficially owned | Percent of class | Accepted date |
|---|---|---|---|---|---|---|---|---|
| Platinum Investment Management Limited | Sydney Australia | 0 | 0 | 0 | 0 | 0 | 0 % | 06/11/2024 |
| Farallon Capital Institutional Partners II, L.P. | California | 0 | 253300 | 0 | 253300 | 253300 | 0.5 % | 17/05/2024 |
| Farallon Capital Institutional Partners III, L.P. | Delaware | 0 | 79875 | 0 | 79875 | 79875 | 0.2 % | 17/05/2024 |
| John R. Warren | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Daniel S. Short | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| William Seybold | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Edric C. Saito | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Thomas G. Roberts, Jr. | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Rajiv A. Patel | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Michael G. Linn | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| David T. Kim | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Nicolas Giauque | France | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Varun N. Gehani | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Richard B. Fried | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Hannah E. Dunn | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Philip D. Dreyfuss | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Joshua J. Dapice | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Farallon F5 | Delaware | 0 | 262600 | 0 | 262600 | 262600 | 0.5 % | 17/05/2024 |
| Farallon Institutional | Delaware | 0 | 172100 | 0 | 172100 | 172100 | 0.4 % | 17/05/2024 |
| Farallon Partners, L.L.C. | Delaware | 0 | 4129341 | 0 | 4129341 | 4129341 | 8.6 % | 17/05/2024 |
| Farallon Capital | Delaware | 0 | 165500 | 0 | 165500 | 165500 | 0.3 % | 17/05/2024 |
| Farallon Capital Partners, L.P. | California | 0 | 1028600 | 0 | 1028600 | 1028600 | 2.1 % | 17/05/2024 |
| Farallon Capital F5 Master I, L.P. | Cayman Islands | 0 | 262600 | 0 | 262600 | 262600 | 0.5 % | 17/05/2024 |
| Farallon Capital Offshore Investors II, L.P. | Cayman Islands | 0 | 1736866 | 0 | 1736866 | 1736866 | 3.6 % | 17/05/2024 |
| Four Crossings Institutional Partners V, L.P. | Delaware | 0 | 172100 | 0 | 172100 | 172100 | 0.4 % | 17/05/2024 |
| Andrew J. M. Spokes | United Kingdom | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Mark C. Wehrly | United States | 0 | 4391941 | 0 | 4391941 | 4391941 | 9.1 % | 17/05/2024 |
| Farallon Capital Institutional Partners, L.P. | California | 0 | 693100 | 0 | 693100 | 693100 | 1.4 % | 17/05/2024 |
| Pura Vida Investments, LLC | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 14/02/2024 |
| Efrem Kamen | USA | 0 | 0 | 0 | 0 | 0 | 0 % | 14/02/2024 |
| RA Capital Healthcare Fund, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 14/02/2024 |
| Rajeev Shah | United States of America | 0 | 0 | 0 | 0 | 0 | 0 % | 14/02/2024 |
| Peter Kolchinsky | United States of America | 0 | 0 | 0 | 0 | 0 | 0 % | 14/02/2024 |
| RA Capital Management, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 14/02/2024 |
| Barclays PLC | England, United Kingdom | 3364657 | 46750 | 3364657 | 46750 | 3411407 | 7.09 % | 14/02/2024 |
| Barclays Bank PLC | England, United Kingdom | 3364657 | 0 | 3364657 | 0 | 3364657 | 6.99 % | 14/02/2024 |
| Barclays Capital Securities Ltd | England, United Kingdom | 0 | 46750 | 0 | 46750 | 46750 | 0.1 % | 14/02/2024 |
| Platinum Investment Management Limited | Sydney Australia | 2744734 | 0 | 2775853 | 0 | 2775853 | 5.77 % | 12/02/2024 |
| Platinum Investment Management Limited | Sydney Australia | 2744734 | 0 | 2775853 | 0 | 2775853 | 5.77 % | 12/02/2024 |
| BlackRock, Inc. | Delaware | 3513704 | 0 | 3574938 | 0 | 3574938 | 7.4 % | 26/01/2024 |
| Eric Varma, MD | USA | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Titanite Investment Management GP LLC | Delaware | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Titanite Investment Management LP | Delaware | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Titanite Master Fund Ltd. | Cayman Islands | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Titanite Investment Management LP | Delaware | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Titanite Investment Management GP LLC | Delaware | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Eric Varma, MD | USA | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Titanite Master Fund Ltd. | Cayman Islands | 1800000 | 0 | 1800000 | 0 | 1800000 | 3.7 % | 25/01/2024 |
| Prosight Management, LP | Delaware | 0 | 3150000 | 0 | 3150000 | 3150000 | 6.6 % | 01/09/2023 |
| Prosight Plus Fund, LP | Delaware | 0 | 824548 | 0 | 824548 | 824548 | 1.7 % | 01/09/2023 |
| Prosight Partners, LLC | Delaware | 0 | 3150000 | 0 | 3150000 | 3150000 | 6.6 % | 01/09/2023 |
| W. Lawrence Hawkins | United States of America | 0 | 3150000 | 0 | 3150000 | 3150000 | 6.6 % | 01/09/2023 |
| Prosight Fund, LP | Delaware | 0 | 279974 | 0 | 279974 | 279974 | 0.6 % | 01/09/2023 |
| Titanite Investment Management GP LLC | Delaware | 2800000 | 0 | 2800000 | 0 | 2800000 | 5.9 % | 21/08/2023 |
| Titanite Investment Management LP | Delaware | 2800000 | 0 | 2800000 | 0 | 2800000 | 5.9 % | 21/08/2023 |
| Eric Varma, MD | USA | 2800000 | 0 | 2800000 | 0 | 2800000 | 5.9 % | 21/08/2023 |
| Titanite Master Fund Ltd. | Cayman Islands | 2800000 | 0 | 2800000 | 0 | 2800000 | 5.9 % | 21/08/2023 |
| Polar Capital LLP | United Kingdom | 3778731 | 0 | 3778731 | 0 | 3778731 | 8.1 % | 13/07/2023 |
| Polar Capital Funds PLC Biotechnology Fund | United Kingdom | 3250000 | 0 | 3250000 | 0 | 3250000 | 6.9 % | 13/07/2023 |
| Polar Capital LLP | United Kingdom | 3778731 | 0 | 3778731 | 0 | 3778731 | 8.1 % | 13/07/2023 |
| Polar Capital Holdings Plc | United Kingdom | 3778731 | 0 | 3778731 | 0 | 3778731 | 8.1 % | 13/07/2023 |
| Polar Capital Holdings Plc | United Kingdom | 3778731 | 0 | 3778731 | 0 | 3778731 | 8.1 % | 13/07/2023 |
| Polar Capital Funds PLC Biotechnology Fund | United Kingdom | 3250000 | 0 | 3250000 | 0 | 3250000 | 6.9 % | 13/07/2023 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 1969961 | 0 | 2342561 | 2342561 | 4.95 % | 09/06/2023 |
| Wellington Management Group LLP | Massachusetts | 0 | 1969961 | 0 | 2342561 | 2342561 | 4.95 % | 09/06/2023 |
| Wellington Group Holdings LLP | Delaware | 0 | 1969961 | 0 | 2342561 | 2342561 | 4.95 % | 09/06/2023 |
| Avidity Partners Management LLC | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Partners Management LP | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Partners Management LLC | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Capital Partners Fund LP | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Capital Partners LLC | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Master Fund LP | Cayman Islands | 0 | 2670285 | 0 | 2670285 | 2670285 | 5.6 % | 25/05/2023 |
| David Witzke | United States America | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Michael Gregory | United States America | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| David Witzke | United States America | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Master Fund LP | Cayman Islands | 0 | 2670285 | 0 | 2670285 | 2670285 | 5.6 % | 25/05/2023 |
| Avidity Capital Partners LLC | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Michael Gregory | United States America | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Partners Management LP | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Avidity Capital Partners Fund LP | Delaware | 0 | 2950000 | 0 | 2950000 | 2950000 | 6.2 % | 25/05/2023 |
| Peter Kolchinsky | United States of America | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| RA Capital Healthcare Fund, L.P. | Delaware | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| Rajeev Shah | United States of America | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| Peter Kolchinsky | United States of America | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| RA Capital Management, L.P. | Delaware | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| RA Capital Healthcare Fund, L.P. | Delaware | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| Rajeev Shah | United States of America | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| RA Capital Management, L.P. | Delaware | 0 | 2577373 | 0 | 2577373 | 2577373 | 5.5 % | 10/04/2023 |
| Efrem Kamen | USA | 0 | 3045900 | 0 | 3045900 | 3045900 | 6.53 % | 14/02/2023 |
| Pura Vida Investments, LLC | Delaware | 0 | 3045900 | 0 | 3045900 | 3045900 | 6.53 % | 14/02/2023 |
| Efrem Kamen | USA | 0 | 3045900 | 0 | 3045900 | 3045900 | 6.53 % | 14/02/2023 |
| Pura Vida Investments, LLC | Delaware | 0 | 3045900 | 0 | 3045900 | 3045900 | 6.53 % | 14/02/2023 |
| The Vanguard Group | Pennsylvania | 0 | 71666 | 2478214 | 114665 | 2592879 | 5.56 % | 09/02/2023 |
| Wellington Management Group LLP | Massachusetts | 0 | 5782714 | 0 | 6453874 | 6453874 | 13.84 % | 06/02/2023 |
| Wellington Management Company LLP | Delaware | 0 | 5734178 | 0 | 6025033 | 6025033 | 12.92 % | 06/02/2023 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 5782714 | 0 | 6453874 | 6453874 | 13.84 % | 06/02/2023 |
| Wellington Group Holdings LLP | Delaware | 0 | 5782714 | 0 | 6453874 | 6453874 | 13.84 % | 06/02/2023 |
| BlackRock, Inc. | Delaware | 4655606 | 0 | 4879306 | 0 | 4879306 | 10.5 % | 23/01/2023 |
| Alger Associates, Inc. | New York | 432675 | 0 | 432675 | 0 | 432675 | 0.9 % | 12/12/2022 |
| Alger Associates, Inc. | New York | 432675 | 0 | 432675 | 0 | 432675 | 0.9 % | 12/12/2022 |
| FMR LLC | Delaware | 404453 | 0 | 405757 | 0 | 405757 | 0.868 % | 12/12/2022 |
| Abigail P. Johnson | United States of America | 0 | 0 | 405757 | 0 | 405757 | 0.868 % | 12/12/2022 |
| Abigail P. Johnson | United States of America | 0 | 0 | 405757 | 0 | 405757 | 0.868 % | 12/12/2022 |
| FMR LLC | Delaware | 404453 | 0 | 405757 | 0 | 405757 | 0.868 % | 12/12/2022 |
| BlackRock, Inc. | Delaware | 4574849 | 0 | 4798539 | 0 | 4798539 | 10.3 % | 07/12/2022 |
| Efrem Kamen | USA | 0 | 2369500 | 0 | 2369500 | 2369500 | 5.08 % | 09/11/2022 |
| Efrem Kamen | USA | 0 | 2369500 | 0 | 2369500 | 2369500 | 5.08 % | 09/11/2022 |
| Pura Vida Investments, LLC | Delaware | 0 | 2369500 | 0 | 2369500 | 2369500 | 5.08 % | 09/11/2022 |
| Pura Vida Investments, LLC | Delaware | 0 | 2369500 | 0 | 2369500 | 2369500 | 5.08 % | 09/11/2022 |
| FMR LLC | Delaware | 4548431 | 0 | 4549787 | 0 | 4549787 | 9.769 % | 11/10/2022 |
| Abigail P. Johnson | United States of America | 0 | 0 | 4549787 | 0 | 4549787 | 9.769 % | 11/10/2022 |
| Abigail P. Johnson | United States of America | 0 | 0 | 4549787 | 0 | 4549787 | 9.769 % | 11/10/2022 |
| FMR LLC | Delaware | 4548431 | 0 | 4549787 | 0 | 4549787 | 9.769 % | 11/10/2022 |
| RA Capital Management, L.P. | Delaware | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| RA Capital Management, L.P. | Delaware | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| RA Capital Healthcare Fund, L.P. | Delaware | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| Rajeev Shah | United States of America | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| RA Capital Healthcare Fund, L.P. | Delaware | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| Peter Kolchinsky | United States of America | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| Peter Kolchinsky | United States of America | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| Rajeev Shah | United States of America | 0 | 3517694 | 0 | 3517694 | 3517694 | 7.7 % | 28/04/2022 |
| Alger Associates, Inc. | New York | 3081660 | 0 | 3081660 | 0 | 3081660 | 6.8 % | 14/02/2022 |
| Alger Associates, Inc. | New York | 3081660 | 0 | 3081660 | 0 | 3081660 | 6.8 % | 14/02/2022 |
| The Vanguard Group | Pennsylvania For | 0 | 81243 | 3305937 | 120567 | 3426504 | 7.51 % | 10/02/2022 |
| Wellington Group Holdings LLP | Delaware | 0 | 4921306 | 0 | 5557968 | 5557968 | 12.17 % | 04/02/2022 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 4921306 | 0 | 5557968 | 5557968 | 12.17 % | 04/02/2022 |
| Wellington Management Group LLP | Massachusetts | 0 | 4921306 | 0 | 5557968 | 5557968 | 12.17 % | 04/02/2022 |
| Wellington Management Company LLP | Delaware | 0 | 4876470 | 0 | 5256208 | 5256208 | 11.51 % | 04/02/2022 |
| BlackRock, Inc. | Delaware | 4302942 | 0 | 4428403 | 0 | 4428403 | 9.7 % | 02/02/2022 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 4155022 | 0 | 4663339 | 4663339 | 10.24 % | 10/11/2021 |
| Wellington Management Company LLP | Delaware | 0 | 4121759 | 0 | 4438190 | 4438190 | 9.75 % | 10/11/2021 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 4155022 | 0 | 4663339 | 4663339 | 10.24 % | 10/11/2021 |
| Wellington Group Holdings LLP | Delaware | 0 | 4155022 | 0 | 4663339 | 4663339 | 10.24 % | 10/11/2021 |
| Wellington Management Group LLP | Massachusetts | 0 | 4155022 | 0 | 4663339 | 4663339 | 10.24 % | 10/11/2021 |
| Wellington Management Group LLP | Massachusetts | 0 | 4155022 | 0 | 4663339 | 4663339 | 10.24 % | 10/11/2021 |
| Wellington Group Holdings LLP | Delaware | 0 | 4155022 | 0 | 4663339 | 4663339 | 10.24 % | 10/11/2021 |
| Wellington Management Company LLP | Delaware | 0 | 4121759 | 0 | 4438190 | 4438190 | 9.75 % | 10/11/2021 |
| Morgan Stanley | Delaware. | 0 | 1009776 | 0 | 1009930 | 1009930 | 2.2 % | 09/11/2021 |
| Morgan Stanley Investment Management Inc. | Delaware. | 0 | 1009776 | 0 | 1009930 | 1009930 | 2.2 % | 09/11/2021 |
| Efrem Kamen | United States America | 0 | 1204664 | 0 | 1204664 | 1204664 | 2.72 % | 16/02/2021 |
| Pura Vida Investments LLC | Delaware | 0 | 1204664 | 0 | 1204664 | 1204664 | 2.72 % | 16/02/2021 |
| Pura Vida Investments LLC | Delaware | 0 | 1204664 | 0 | 1204664 | 1204664 | 2.72 % | 16/02/2021 |
| Efrem Kamen | United States America | 0 | 1204664 | 0 | 1204664 | 1204664 | 2.72 % | 16/02/2021 |
| Alger Group Holdings, LLC | Delaware | 2533689 | 0 | 2533689 | 0 | 2533689 | 5.75 % | 16/02/2021 |
| Fred Alger Management, LLC | Delaware | 2533689 | 0 | 2533689 | 0 | 2533689 | 5.75 % | 16/02/2021 |
| Alger Associates, Inc. | New York | 2533689 | 0 | 2533689 | 0 | 2533689 | 5.75 % | 16/02/2021 |
| Fred Alger Management, LLC | Delaware | 2533689 | 0 | 2533689 | 0 | 2533689 | 5.75 % | 16/02/2021 |
| Alger Group Holdings, LLC | Delaware | 2533689 | 0 | 2533689 | 0 | 2533689 | 5.75 % | 16/02/2021 |
| Alger Associates, Inc. | New York | 2533689 | 0 | 2533689 | 0 | 2533689 | 5.75 % | 16/02/2021 |
| ARK Investment Management LLC | Delaware, United States | 3465066 | 447044 | 3917273 | 0 | 3917273 | 8.89 % | 16/02/2021 |
| Eric Bannasch | United States of America | 0 | 0 | 0 | 0 | 0 | 0 % | 12/02/2021 |
| Cadian Capital Management GP, LLC | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 12/02/2021 |
| Cadian Capital Management, LP | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 12/02/2021 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 1245673 | 0 | 1330140 | 1330140 | 3.02 % | 11/02/2021 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 1245673 | 0 | 1330140 | 1330140 | 3.02 % | 11/02/2021 |
| The Vanguard Group | Pennsylvania | 0 | 94347 | 2174789 | 128178 | 2302967 | 5.23 % | 10/02/2021 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 1330140 | 0 | 1330140 | 1330140 | 3.02 % | 05/02/2021 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 1330140 | 0 | 1330140 | 1330140 | 3.02 % | 05/02/2021 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 1330140 | 0 | 1330140 | 1330140 | 3.02 % | 05/02/2021 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 1330140 | 0 | 1330140 | 1330140 | 3.02 % | 05/02/2021 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 2101948 | 0 | 2333190 | 2333190 | 5.29 % | 11/01/2021 |
| Wellington Group Holdings LLP | Delaware | 0 | 2101948 | 0 | 2333190 | 2333190 | 5.29 % | 11/01/2021 |
| Wellington Management Company LLP | Delaware | 0 | 2093393 | 0 | 2252812 | 2252812 | 5.11 % | 11/01/2021 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 2101948 | 0 | 2333190 | 2333190 | 5.29 % | 11/01/2021 |
| Wellington Group Holdings LLP | Delaware | 0 | 2101948 | 0 | 2333190 | 2333190 | 5.29 % | 11/01/2021 |
| Wellington Management Group LLP | Massachusetts | 0 | 2101948 | 0 | 2333190 | 2333190 | 5.29 % | 11/01/2021 |
| Wellington Management Group LLP | Massachusetts | 0 | 2101948 | 0 | 2333190 | 2333190 | 5.29 % | 11/01/2021 |
| Wellington Management Company LLP | Delaware | 0 | 2093393 | 0 | 2252812 | 2252812 | 5.11 % | 11/01/2021 |
| BlackRock, Inc. | Delaware | 4333483 | 0 | 4450774 | 0 | 4450774 | 10.1 % | 08/01/2021 |
| ARK Investment Management LLC | Delaware, United States | 3405367 | 408251 | 3822106 | 0 | 3822106 | 10.06 % | 09/10/2020 |
| ARK Investment Management LLC | Delaware, United States | 3405367 | 408251 | 3822106 | 0 | 3822106 | 10.06 % | 09/10/2020 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 1920550 | 0 | 1920550 | 1920550 | 5.06 % | 09/10/2020 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 1920550 | 0 | 1920550 | 1920550 | 5.06 % | 09/10/2020 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 1920550 | 0 | 1920550 | 1920550 | 5.06 % | 09/10/2020 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 1920550 | 0 | 1920550 | 1920550 | 5.06 % | 09/10/2020 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 1730935 | 0 | 1920550 | 1920550 | 5.06 % | 08/10/2020 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 1730935 | 0 | 1920550 | 1920550 | 5.06 % | 08/10/2020 |
| Wellington Management Company LLP | Delaware | 0 | 3503710 | 0 | 3803710 | 3803710 | 10.08 % | 10/08/2020 |
| Wellington Group Holdings LLP | Delaware | 0 | 3522811 | 0 | 3944506 | 3944506 | 10.45 % | 10/08/2020 |
| Wellington Management Company LLP | Delaware | 0 | 3503710 | 0 | 3803710 | 3803710 | 10.08 % | 10/08/2020 |
| Wellington Management Group LLP | Massachusetts | 0 | 3522811 | 0 | 3944506 | 3944506 | 10.45 % | 10/08/2020 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 3522811 | 0 | 3944506 | 3944506 | 10.45 % | 10/08/2020 |
| Wellington Group Holdings LLP | Delaware | 0 | 3522811 | 0 | 3944506 | 3944506 | 10.45 % | 10/08/2020 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 3522811 | 0 | 3944506 | 3944506 | 10.45 % | 10/08/2020 |
| Wellington Management Group LLP | Massachusetts | 0 | 3522811 | 0 | 3944506 | 3944506 | 10.45 % | 10/08/2020 |
| Abigail P. Johnson | United States of America | 0 | 0 | 4069962 | 0 | 4069962 | 10.778 % | 10/06/2020 |
| FMR LLC | Delaware | 336563 | 0 | 4069962 | 0 | 4069962 | 10.778 % | 10/06/2020 |
| Abigail P. Johnson | United States of America | 0 | 0 | 4069962 | 0 | 4069962 | 10.778 % | 10/06/2020 |
| FMR LLC | Delaware | 336563 | 0 | 4069962 | 0 | 4069962 | 10.778 % | 10/06/2020 |
| ARK Investment Management LLC | Delaware, United States | 2839195 | 204603 | 3055316 | 0 | 3055316 | 8.55 % | 14/02/2020 |
| ARK Investment Management LLC | Delaware United States | 2839195 | 204603 | 3055316 | 0 | 3055316 | 8.55 % | 14/02/2020 |
| Morgan Stanley # | Delaware | 0 | 4128446 | 0 | 4128646 | 4128646 | 11.6 % | 14/02/2020 |
| Morgan Stanley Investment Management Inc. # | Delaware | 0 | 4128446 | 0 | 4128646 | 4128646 | 11.6 % | 14/02/2020 |
| Morgan Stanley Insight Fund # | Massachusetts | 0 | 2184022 | 0 | 2184022 | 2187022 | 6.1 % | 14/02/2020 |
| Cadian Capital Management, LP | Delaware | 0 | 1851434 | 0 | 1851434 | 1851434 | 5.2 % | 13/02/2020 |
| Eric Bannasch | United States America | 0 | 1851434 | 0 | 1851434 | 1851434 | 5.2 % | 13/02/2020 |
| Cadian Capital Management GP, LLC | Delaware | 0 | 1851434 | 0 | 1851434 | 1851434 | 5.2 % | 13/02/2020 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 3023350 | 0 | 3830602 | 3830602 | 10.72 % | 12/02/2020 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 3023350 | 0 | 3830602 | 3830602 | 10.72 % | 12/02/2020 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 3830602 | 0 | 3830602 | 3830602 | 10.72 % | 12/02/2020 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 3830929 | 0 | 3830929 | 3830929 | 10.72 % | 12/02/2020 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 3830929 | 0 | 3830929 | 3830929 | 10.72 % | 12/02/2020 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 3830602 | 0 | 3830602 | 3830602 | 10.72 % | 12/02/2020 |
| The Vanguard Group | Pennsylvania | 65737 | 2515 | 1780215 | 64542 | 1844757 | 5.16 % | 11/02/2020 |
| Efrem Kamen | United States of America | 0 | 1963401 | 0 | 1963401 | 1963401 | 5.37 % | 17/01/2020 |
| Pura Vida Investments, LLC | Delaware | 0 | 1963401 | 0 | 1963401 | 1963401 | 5.37 % | 17/01/2020 |
| Pura Vida Investments, LLC | Delaware | 0 | 1963401 | 0 | 1963401 | 1963401 | 5.37 % | 17/01/2020 |
| Efrem Kamen | United States of America | 0 | 1963401 | 0 | 1963401 | 1963401 | 5.37 % | 17/01/2020 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 630782 | 0 | 699772 | 699772 | 1.96 % | 08/01/2020 |
| Wellington Management Group LLP | Massachusetts | 0 | 630782 | 0 | 699772 | 699772 | 1.96 % | 08/01/2020 |
| Wellington Group Holdings LLP | Delaware | 0 | 630782 | 0 | 699772 | 699772 | 1.96 % | 08/01/2020 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 630782 | 0 | 699772 | 699772 | 1.96 % | 08/01/2020 |
| Wellington Management Group LLP | Massachusetts | 0 | 630782 | 0 | 699772 | 699772 | 1.96 % | 08/01/2020 |
| Wellington Group Holdings LLP | Delaware | 0 | 630782 | 0 | 699772 | 699772 | 1.96 % | 08/01/2020 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 3904451 | 0 | 3904451 | 3904451 | 11.02 % | 10/10/2019 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 3917182 | 0 | 3917182 | 3917182 | 11.05 % | 10/10/2019 |
| Sumitomo Mitsui Trust Holdings, Inc. (“SMTH”) | Japan | 0 | 3917182 | 0 | 3917182 | 3917182 | 11.05 % | 10/10/2019 |
| Nikko Asset Management Co., Ltd. (“NAM”) | Japan | 0 | 3904451 | 0 | 3904451 | 3904451 | 11.02 % | 10/10/2019 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 3077468 | 0 | 3904451 | 3904451 | 11.02 % | 09/10/2019 |
| Nikko Asset Management Americas, Inc. | USA | 0 | 3077468 | 0 | 3904451 | 3904451 | 11.02 % | 09/10/2019 |
| Morgan Stanley Insight Fund | Massachusetts. | 0 | 1954357 | 0 | 1954357 | 1954357 | 5.5 % | 12/08/2019 |
| Morgan Stanley | Delaware. | 0 | 3949261 | 0 | 3949461 | 3949461 | 11.1 % | 12/08/2019 |
| Morgan Stanley Investment Management Inc. | Delaware. | 0 | 3949261 | 0 | 3949461 | 3949461 | 11.1 % | 12/08/2019 |
| ARK Investment Management LLC | Delaware, United States | 3140420 | 91512 | 3140420 | 98272 | 3238692 | 10.5 % | 14/02/2019 |
| Morgan Stanley | Delaware. | 376187 | 0 | 415055 | 416674 | 1.3 % | 09/11/2018 | |
| Wellington Management Company LLP | Delaware | 0 | 1309193 | 0 | 1419729 | 1419729 | 5.58 % | 10/04/2018 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 1309193 | 0 | 1448480 | 1448480 | 5.69 % | 10/04/2018 |
| Wellington Group Holdings LLP | Delaware | 0 | 1309193 | 0 | 1448480 | 1448480 | 5.69 % | 10/04/2018 |
| Wellington Management Group LLP | Massachusetts | 0 | 1309193 | 0 | 1448480 | 1448480 | 5.69 % | 10/04/2018 |
| Wellington Management Company LLP | Delaware | 0 | 1309193 | 0 | 1419729 | 1419729 | 5.58 % | 10/04/2018 |
| Wellington Group Holdings LLP | Delaware | 0 | 1309193 | 0 | 1448480 | 1448480 | 5.69 % | 10/04/2018 |
| Wellington Management Group LLP | Massachusetts | 0 | 1309193 | 0 | 1448480 | 1448480 | 5.69 % | 10/04/2018 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 1309193 | 0 | 1448480 | 1448480 | 5.69 % | 10/04/2018 |
| Integrated Assets, Ltd. | 121023 | 0.5 % | 20/03/2018 | |||||
| Integrated Assets II LLC | 349211 | 1.4 % | 20/03/2018 | |||||
| Integrated Core Strategies (US) LLC | 552754 | 2.2 % | 20/03/2018 | |||||
| ICS Opportunities, Ltd. | 45922 | 0.2 % | 20/03/2018 | |||||
| Integrated Core Strategies (US) LLC | 552754 | 2.2 % | 20/03/2018 | |||||
| Integrated Assets II LLC | 349211 | 1.4 % | 20/03/2018 | |||||
| Integrated Assets, Ltd. | 121023 | 0.5 % | 20/03/2018 | |||||
| Millennium International Management LP | 166945 | 0.7 % | 20/03/2018 | |||||
| Millennium Management LLC | 1068910 | 4.2 % | 20/03/2018 | |||||
| Millennium Group Management LLC | 1068910 | 4.2 % | 20/03/2018 | |||||
| Israel A. Englander | 1068910 | 4.2 % | 20/03/2018 | |||||
| Israel A. Englander | 1068910 | 4.2 % | 20/03/2018 | |||||
| Millennium Group Management LLC | 1068910 | 4.2 % | 20/03/2018 | |||||
| Millennium Management LLC | 1068910 | 4.2 % | 20/03/2018 | |||||
| Millennium International Management LP | 166945 | 0.7 % | 20/03/2018 | |||||
| ICS Opportunities, Ltd. | 45922 | 0.2 % | 20/03/2018 | |||||
| Morgan Stanley Capital Services LLC | Delaware. | 0 | 1210798 | 0 | 1210798 | 1210798 | 4.7 % | 13/02/2018 |
| Morgan Stanley | Delaware. | 0 | 1605651 | 0 | 1602375 | 1606251 | 6.3 % | 13/02/2018 |
| Foresite Capital Fund III, L.P. | Delaware | 0 | 5 | 0 | 7 | 0 | 0 % | 13/02/2018 |
| James Tananbaum | United States | 0 | 5 | 0 | 7 | 0 | 0 % | 13/02/2018 |
| Foresite Capital Fund II, L.P. | Delaware | 0 | 5 | 0 | 7 | 0 | 0 % | 13/02/2018 |
| Foresite Capital Management II, LLC | Delaware | 0 | 5 | 0 | 7 | 0 | 0 % | 13/02/2018 |
| Foresite Capital Management III, LLC | Delaware | 0 | 5 | 0 | 7 | 0 | 0 % | 13/02/2018 |
| Wellington Management Company LLP | Delaware | 0 | 3036012 | 0 | 3432347 | 3432347 | 13.52 % | 08/02/2018 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 3036012 | 0 | 3535435 | 3535435 | 13.93 % | 08/02/2018 |
| Wellington Management Group LLP | Massachusetts | 0 | 3036012 | 0 | 3535435 | 3535435 | 13.93 % | 08/02/2018 |
| Wellington Group Holdings LLP | Delaware | 0 | 3036012 | 0 | 3535435 | 3535435 | 13.93 % | 08/02/2018 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 707477 | 0 | 1050851 | 1050851 | 4.1 % | 24/01/2018 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 24/01/2018 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 24/01/2018 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 707477 | 0 | 1050851 | 1050851 | 4.1 % | 24/01/2018 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 24/01/2018 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 24/01/2018 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 707477 | 0 | 1050851 | 1050851 | 4.1 % | 24/01/2018 |
| S LCS, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 24/01/2018 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 24/01/2018 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 707477 | 0 | 1050851 | 1050851 | 4.1 % | 24/01/2018 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 24/01/2018 |
| S LCS, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 24/01/2018 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 18/10/2017 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 18/10/2017 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 18/10/2017 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 18/10/2017 |
| S LCS, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 18/10/2017 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 1137001 | 0 | 1532697 | 1532697 | 6.1 % | 18/10/2017 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 1137001 | 0 | 1532697 | 1532697 | 6.1 % | 18/10/2017 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 1137001 | 0 | 1532697 | 1532697 | 6.1 % | 18/10/2017 |
| S LCS, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 18/10/2017 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 18/10/2017 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 1137001 | 0 | 1532697 | 1532697 | 6.1 % | 18/10/2017 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 18/10/2017 |
| Wellington Group Holdings LLP | Delaware | 0 | 2655920 | 0 | 3057535 | 3057535 | 12.13 % | 10/10/2017 |
| Wellington Management Company LLP | Delaware | 0 | 2655920 | 0 | 2978585 | 2978585 | 11.82 % | 10/10/2017 |
| Wellington Management Group LLP | Massachusetts | 0 | 2655920 | 0 | 3057535 | 3057535 | 12.13 % | 10/10/2017 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 2655920 | 0 | 3057535 | 3057535 | 12.13 % | 10/10/2017 |
| Wellington Investment Advisors Holdings LLP | Delaware | 0 | 2655920 | 0 | 3057535 | 3057535 | 12.13 % | 10/10/2017 |
| Wellington Group Holdings LLP | Delaware | 0 | 2655920 | 0 | 3057535 | 3057535 | 12.13 % | 10/10/2017 |
| Wellington Management Group LLP | Massachusetts | 0 | 2655920 | 0 | 3057535 | 3057535 | 12.13 % | 10/10/2017 |
| Wellington Management Company LLP | Delaware | 0 | 2655920 | 0 | 2978585 | 2978585 | 11.82 % | 10/10/2017 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 02/10/2017 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 899464 | 0 | 1233778 | 1233778 | 4.9 % | 02/10/2017 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 02/10/2017 |
| S LCS, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 02/10/2017 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 899464 | 0 | 1233778 | 1233778 | 4.9 % | 02/10/2017 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 02/10/2017 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 02/10/2017 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 899464 | 0 | 1233778 | 1233778 | 4.9 % | 02/10/2017 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 899464 | 0 | 1233778 | 1233778 | 4.9 % | 02/10/2017 |
| S LCS, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 02/10/2017 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 02/10/2017 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 02/10/2017 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 812685 | 0 | 1098126 | 1098126 | 5.1 % | 09/06/2017 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 09/06/2017 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 09/06/2017 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 09/06/2017 |
| S John A. Levin | United States America | 0 | 0 | 0 | 0 | 10 | 0 % | 09/06/2017 |
| S LCS L/S, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 09/06/2017 |
| S LCS Event Partners, LLC | A Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 09/06/2017 |
| S LCS, LLC | A Delaware | 0 | 41338 | 0 | 41338 | 41338 | 1 % | 09/06/2017 |
| S Levin Capital Strategies GP, LLC | Delaware | 0 | 812685 | 0 | 1098126 | 1098126 | 5.1 % | 09/06/2017 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 812685 | 0 | 1098126 | 1098126 | 5.1 % | 09/06/2017 |
| S Levin Capital Strategies, L.P. | A Delaware | 0 | 812685 | 0 | 1098126 | 1098126 | 5.1 % | 09/06/2017 |
| S LCS, LLC | A Delaware | 0 | 41338 | 0 | 41338 | 41338 | 1 % | 09/06/2017 |
| GERARD H. LANGELER | United States of America | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| BILL FUNCANNON | United States of America | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| CHARLES P. WAITE, JR. | United States of America | 29750 | 0 | 29750 | 0 | 29750 | 0.1 % | 15/02/2017 |
| OVMC VII, L.L.C. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| OVMC VI, L.L.C. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| OVP VII ENTREPRENEURS FUND, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| OVP VENTURE PARTNERS VII, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| OVP VI ENTREPRENEURS FUND, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| OVP VENTURE PARTNERS VI, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 15/02/2017 |
| Foresite Capital Fund II, L.P. | Delaware | 679033 | 679033 | 679033 | 679033 | 679033 | 3.2 % | 13/02/2017 |
| Foresite Capital Management III, LLC | Delaware | 438133 | 438133 | 438133 | 438133 | 438133 | 2.1 % | 13/02/2017 |
| Foresite Capital Fund III, L.P. | Delaware | 438133 | 438133 | 438133 | 438133 | 438133 | 2.1 % | 13/02/2017 |
| Foresite Capital Management II, LLC | Delaware | 679033 | 679033 | 679033 | 679033 | 679033 | 3.2 % | 13/02/2017 |
| James Tananbaum | United States | 1117166 | 1117166 | 1117166 | 1117166 | 1117166 | 5.3 % | 13/02/2017 |
| Cadian Capital Management, LP | Delaware | 0 | 1985592 | 0 | 1985592 | 1985592 | 9.5 % | 13/02/2017 |
| Cadian Capital Management GP, LLC | Delaware | 0 | 1985592 | 0 | 1985592 | 1985592 | 9.5 % | 13/02/2017 |
| Eric Bannasch | United States America | 0 | 1985592 | 0 | 1985592 | 1985592 | 9.5 % | 13/02/2017 |
| Morgan Stanley # | organization is Delaware | 1588780 | 59522 | 0 | 1652242 | 1652242 | 7.8 % | 13/02/2017 |
| Morgan Stanley Capital Services LLC #133292567 | organization is Delaware | 1195787 | 0 | 0 | 1195787 | 1195787 | 5.6 % | 13/02/2017 |
| Draper Fisher Jurvetson Fund VII, L.P. | Cayman Islands | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| Draper Fisher Jurvetson Fund VII Partners, L.P. | Cayman Islands | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| DFJ Fund VII, Ltd. | Cayman Islands | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| Draper Fisher Jurvetson Partners VII, LLC | California | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| Draper Associates, L.P. | California | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| Draper Associates, Inc. | California | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| Timothy C. Draper | California | 0 | 15079 | 0 | 15079 | 15079 | 0.07 % | 31/01/2017 |
| Draper Associates Riskmasters Fund II, LLC | California | 0 | 12905 | 0 | 12905 | 12905 | 0.06 % | 31/01/2017 |
| Draper Associates Riskmasters Fund, LLC | California | 0 | 2174 | 0 | 2174 | 2174 | 0.01 % | 31/01/2017 |
| John H. N. Fisher | United States | 0 | 0 | 0 | 0 | 0 | 0 % | 31/01/2017 |
| Stephen T. Jurvetson | United States | 9660 | 0 | 9660 | 0 | 9660 | 0.05 % | 31/01/2017 |
| John Fisher and Jennifer Caldwell Living Trust dated 1/7/00, as amended and restated 3/27/08 | United States | 0 | 16135 | 0 | 16135 | 16135 | 0.08 % | 31/01/2017 |
| Foresite Capital Management II, LLC | Delaware | 727857 | 727857 | 727857 | 727857 | 727857 | 3.7 % | 18/07/2016 |
| Foresite Capital Fund II, L.P. | Delaware | 727857 | 727857 | 727857 | 727857 | 727857 | 3.7 % | 18/07/2016 |
| Foresite Capital Fund III, L.P. | Delaware | 434500 | 434500 | 434500 | 434500 | 434500 | 2.2 % | 18/07/2016 |
| Foresite Capital Management III, LLC | Delaware | 434500 | 434500 | 434500 | 434500 | 434500 | 2.2 % | 18/07/2016 |
| James Tananbaum | United States | 1162357 | 1162357 | 1162357 | 1162357 | 1162357 | 5.9 % | 18/07/2016 |
| Foresite Capital Management III, LLC | Delaware | 434500 | 434500 | 434500 | 434500 | 434500 | 2.2 % | 18/07/2016 |
| Foresite Capital Fund III, L.P. | Delaware | 434500 | 434500 | 434500 | 434500 | 434500 | 2.2 % | 18/07/2016 |
| Foresite Capital Management II, LLC | Delaware | 727857 | 727857 | 727857 | 727857 | 727857 | 3.7 % | 18/07/2016 |
| Foresite Capital Fund II, L.P. | Delaware | 727857 | 727857 | 727857 | 727857 | 727857 | 3.7 % | 18/07/2016 |
| James Tananbaum | United States | 1162357 | 1162357 | 1162357 | 1162357 | 1162357 | 5.9 % | 18/07/2016 |
| Redmile Group, LLC | DELAWARE | 1357692 | 0 | 1357692 | 0 | 1357692 | 6.96 % | 16/02/2016 |
| JEREMY C. GREEN | UNITED STATES | 0 | 1357692 | 0 | 1357692 | 1357692 | 6.96 % | 16/02/2016 |
| Redmile Group, LLC | DELAWARE | 1357692 | 0 | 1357692 | 0 | 1357692 | 6.96 % | 16/02/2016 |
| JEREMY C. GREEN | UNITED STATES | 0 | 1357692 | 0 | 1357692 | 1357692 | 6.96 % | 16/02/2016 |
| S Deerfield Special Situations International Master Fund, L.P. | British Virgin Islands | 0 | 0 | 0 | 0 | 0 | 0 % | 16/02/2016 |
| S Deerfield Management Company, L.P. | Delaware | 0 | 880622 | 0 | 880622 | 880622 | 4.51 % | 16/02/2016 |
| S Deerfield Special Situations Fund, L.P. | Delaware | 0 | 880622 | 0 | 880622 | 880622 | 4.51 % | 16/02/2016 |
| S James E. Flynn | United States | 0 | 880622 | 0 | 880622 | 880622 | 4.51 % | 16/02/2016 |
| S Deerfield Mgmt, L.P. | Delaware | 0 | 880622 | 0 | 880622 | 880622 | 4.51 % | 16/02/2016 |
| Eric Bannasch | United States of America | 0 | 1323102 | 0 | 1323102 | 1323102 | 6.8 % | 12/02/2016 |
| Cadian Capital Management GP, LLC | Delaware | 0 | 1323102 | 0 | 1323102 | 1323102 | 6.8 % | 12/02/2016 |
| Cadian Capital Management, LP | Delaware | 0 | 1323102 | 0 | 1323102 | 1323102 | 6.8 % | 12/02/2016 |
| Morgan Stanley | The state of organization is Delaware. | 85054 | 0 | 1598178 | 1598178 | 8.2 % | 05/02/2016 | |
| Morgan Stanley Capital Services LLC | The state of organization is Delaware. | 0 | 0 | 1163293 | 1163293 | 6 % | 05/02/2016 | |
| Draper Associates, Inc. | California | 0 | 32154 | 0 | 32154 | 32154 | 0.16 % | 28/01/2016 |
| Draper Fisher Jurvetson Fund VII Partners, L.P. | Cayman Islands | 0 | 1789450 | 0 | 1789450 | 1789450 | 9.17 % | 28/01/2016 |
| Draper Fisher Jurvetson Fund VII, L.P. | Cayman Islands | 0 | 1789450 | 0 | 1789450 | 1789450 | 9.17 % | 28/01/2016 |
| John H. N. Fisher | United States | 0 | 1815546 | 0 | 1815546 | 1815546 | 9.31 % | 28/01/2016 |
| Draper Associates Riskmasters Fund II, LLC | California | 0 | 12002 | 0 | 12002 | 12002 | 0.06 % | 28/01/2016 |
| Draper Associates, L.P. | California | 0 | 32154 | 0 | 32154 | 32154 | 0.16 % | 28/01/2016 |
| Draper Fisher Jurvetson Partners VII, LLC | California | 0 | 26096 | 0 | 26096 | 26096 | 0.13 % | 28/01/2016 |
| DFJ Fund VII, Ltd. | Cayman Islands | 0 | 1789450 | 0 | 1789450 | 1789450 | 9.17 % | 28/01/2016 |
| Draper Associates Riskmasters Fund, LLC | California | 0 | 2385 | 0 | 2385 | 2385 | 0.01 % | 28/01/2016 |
| Stephen T. Jurvetson | United States | 0 | 1815546 | 0 | 1815546 | 1815546 | 9.31 % | 28/01/2016 |
| Timothy C. Draper | California | 0 | 1862087 | 0 | 1862087 | 1862087 | 9.54 % | 28/01/2016 |
| Morgan Stanley | The state of organization is Delaware. | 908273 | 11757 | 0 | 922585 | 922585 | 5 % | 05/06/2015 |
| Eric Bannasch | United States of America | 0 | 1241736 | 0 | 1241736 | 1241736 | 6.7 % | 26/05/2015 |
| Cadian Fund, LP | Delaware | 0 | 710278 | 0 | 710278 | 710278 | 3.9 % | 26/05/2015 |
| Eric Bannasch | United States of America | 0 | 1241736 | 0 | 1241736 | 1241736 | 6.7 % | 26/05/2015 |
| Cadian Capital Management, LP | Delaware | 0 | 1241736 | 0 | 1241736 | 1241736 | 6.7 % | 26/05/2015 |
| Cadian Fund, LP | Delaware | 0 | 710278 | 0 | 710278 | 710278 | 3.9 % | 26/05/2015 |
| Cadian Capital Management, LP | Delaware | 0 | 1241736 | 0 | 1241736 | 1241736 | 6.7 % | 26/05/2015 |
| OVP VENTURE PARTNERS VII, L.P. | Delaware | 575625 | 5 | 575625 | 7 | 575625 | 3.1 % | 17/02/2015 |
| OVMC VI, L.L.C. | Delaware | 1063775 | 5 | 1063775 | 7 | 1063775 | 5.8 % | 17/02/2015 |
| OVP VENTURE PARTNERS VI, L.P. | Delaware | 1063775 | 5 | 1063775 | 7 | 1063775 | 5.8 % | 17/02/2015 |
| OVP VI ENTREPRENEURS FUND, L.P. | Delaware | 0 | 5 | 0 | 7 | 0 | 0 % | 17/02/2015 |
| OVP VII ENTREPRENEURS FUND, L.P. | Delaware | 1484 | 5 | 1484 | 7 | 1484 | 0 % | 17/02/2015 |
| BILL FUNCANNON | United States of America | 0 | 577109 | 0 | 577109 | 577109 | 3.2 % | 17/02/2015 |
| GERARD H. LANGELER | United States of America | 0 | 1640884 | 0 | 1640884 | 1640884 | 9 % | 17/02/2015 |
| CHARLES P. WAITE, JR. | United States of America | 13153 | 1640884 | 13153 | 1640884 | 1654037 | 9 % | 17/02/2015 |
| OVMC VII, L.L.C. | Delaware | 577109 | 5 | 577109 | 7 | 577109 | 3.2 % | 17/02/2015 |
| JEREMY C. GREEN | UNITED STATES | 0 | 1266538 | 0 | 1266538 | 1266538 | 6.96 % | 17/02/2015 |
| Redmile Group, LLC | DELAWARE | 1266538 | 0 | 1266538 | 0 | 1266538 | 6.96 % | 17/02/2015 |
| JEREMY C. GREEN | UNITED STATES | 0 | 1266538 | 0 | 1266538 | 1266538 | 6.96 % | 17/02/2015 |
| Redmile Group, LLC | DELAWARE | 1266538 | 0 | 1266538 | 0 | 1266538 | 6.96 % | 17/02/2015 |
| Deerfield Special Situations International Master Fund, L.P. | British Virgin Islands | 0 | 419213 | 0 | 419213 | 419213 | 2.3 % | 17/02/2015 |
| James E. Flynn | United States | 0 | 923378 | 0 | 923378 | 923378 | 5.07 % | 17/02/2015 |
| Deerfield Mgmt, L.P. | Delaware | 0 | 923378 | 0 | 923378 | 923378 | 5.07 % | 17/02/2015 |
| Deerfield Management Company, L.P. | Delaware | 0 | 923378 | 0 | 923378 | 923378 | 5.07 % | 17/02/2015 |
| Deerfield Partners, L.P. | Delaware | 0 | 0 | 0 | 0 | 0 | 0 % | 17/02/2015 |
| Deerfield Special Situations Fund, L.P. | Delaware | 0 | 504165 | 0 | 504165 | 504165 | 2.77 % | 17/02/2015 |
| Deerfield International Master Fund, L.P. | British Virgin Islands | 0 | 0 | 0 | 0 | 0 | 0 % | 17/02/2015 |
| Timothy C. Draper | California | 0 | 1861691 | 0 | 1861691 | 1861691 | 10.38 % | 12/02/2014 |
| Stephen T. Jurvetson | United States | 0 | 1815546 | 0 | 1815546 | 1815546 | 10.12 % | 12/02/2014 |
| Draper Fisher Jurvetson Fund VII, L.P. | Cayman Islands | 0 | 1789450 | 0 | 1789450 | 1789450 | 9.98 % | 12/02/2014 |
| DFJ Fund VII, Ltd. | Cayman Islands | 0 | 1789450 | 0 | 1789450 | 1789450 | 9.98 % | 12/02/2014 |
| Draper Fisher Jurvetson Fund VII Partners, L.P. | Cayman Islands | 0 | 1789450 | 0 | 1789450 | 1789450 | 9.98 % | 12/02/2014 |
| Draper Associates Riskmasters Fund, LLC | California | 0 | 1989 | 0 | 1989 | 1989 | 0.01 % | 12/02/2014 |
| Draper Associates Riskmasters Fund II, LLC | California | 0 | 12002 | 0 | 12002 | 12002 | 0.07 % | 12/02/2014 |
| Draper Associates, Inc. | California | 0 | 32154 | 0 | 32154 | 32154 | 0.18 % | 12/02/2014 |
| Draper Associates, L.P. | California | 0 | 32154 | 0 | 32154 | 32154 | 0.18 % | 12/02/2014 |
| Draper Fisher Jurvetson Partners VII, LLC | California | 0 | 26096 | 0 | 26096 | 26096 | 0.15 % | 12/02/2014 |
| John H. N. Fisher | United States | 0 | 1815546 | 0 | 1815546 | 1815546 | 10.12 % | 12/02/2014 |
| James E. Flynn | United States | 0 | 894240 | 0 | 894240 | 894240 | 5.08 % | 30/01/2014 |
| Deerfield Special Situations International Master Fund, L.P. | British Virgin Islands | 0 | 302363 | 0 | 302363 | 302363 | 1.72 % | 30/01/2014 |
| James E. Flynn | United States | 0 | 894240 | 0 | 894240 | 894240 | 5.08 % | 30/01/2014 |
| Deerfield Partners, L.P. | Delaware | 0 | 97381 | 0 | 97381 | 97381 | 0.55 % | 30/01/2014 |
| Deerfield Special Situations Fund, L.P. | Delaware | 0 | 372552 | 0 | 372552 | 372552 | 2.12 % | 30/01/2014 |
| Deerfield International Master Fund, L.P. | British Virgin Islands | 0 | 121944 | 0 | 121944 | 121944 | 0.69 % | 30/01/2014 |
| Deerfield Mgmt, L.P. | Delaware | 0 | 894240 | 0 | 894240 | 894240 | 5.08 % | 30/01/2014 |
| Deerfield Management Company, L.P. | Delaware | 0 | 894240 | 0 | 894240 | 894240 | 5.08 % | 30/01/2014 |
| Deerfield Partners, L.P. | Delaware | 0 | 97381 | 0 | 97381 | 97381 | 0.55 % | 30/01/2014 |
| Deerfield Special Situations Fund, L.P. | Delaware | 0 | 372552 | 0 | 372552 | 372552 | 2.12 % | 30/01/2014 |
| Deerfield International Master Fund, L.P. | British Virgin Islands | 0 | 121944 | 0 | 121944 | 121944 | 0.69 % | 30/01/2014 |
| Deerfield Mgmt, L.P. | Delaware | 0 | 894240 | 0 | 894240 | 894240 | 5.08 % | 30/01/2014 |
| Deerfield Management Company, L.P. | Delaware | 0 | 894240 | 0 | 894240 | 894240 | 5.08 % | 30/01/2014 |
| Deerfield Special Situations International Master Fund, L.P. | British Virgin Islands | 0 | 302363 | 0 | 302363 | 302363 | 1.72 % | 30/01/2014 |