PRTK

Paratek Pharmaceuticals, Inc. PRTK

Trading inactive

Individual Beneficiary

Name of reporting person Citizenship or organization Sole voting power Shared voting power Sole dispositive power Shared dispositive power Amount beneficially owned Percent of class Accepted date
Continental General Holdings LLC Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Michael Gorzynski Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Continental Insurance Group, Ltd. Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Michael Gorzynski Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Continental General Insurance Company Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Continental General Insurance Company Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Continental Insurance Group, Ltd. Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
Continental General Holdings LLC Texas 0 0 0 3693981 3693981 6.4 % 05/09/2023
NexPoint Asset Management, L.P. Delaware 0 2445770 0 2445770 2445770 4.27 % 30/03/2023
NexPoint Advisors, L.P. Delaware 0 50000 0 50000 50000 0.09 % 30/03/2023
The Dugaboy Investment Trust Delaware 0 2889060 0 2889060 2889060 5.05 % 30/03/2023
NexPoint Real Estate Opportunities, LLC 0 50000 0 50000 50000 0.09 % 30/03/2023
James D. Dondero 0 6692447 0 6692447 6692447 11.69 % 30/03/2023
Nancy Marie Dondero 0 2889060 0 2889060 2889060 5.05 % 30/03/2023
The Dugaboy Investment Trust 0 2889060 0 2889060 2889060 5.05 % 30/03/2023
NexPoint Advisors, L.P. 0 50000 0 50000 50000 0.09 % 30/03/2023
NexPoint Asset Management, L.P. 0 2445770 0 2445770 2445770 4.27 % 30/03/2023
NexPoint Climate Tech Fund Massachusetts 0 64770 0 64770 64770 0.11 % 30/03/2023
Nancy Marie Dondero United States 0 2889060 0 2889060 2889060 5.05 % 30/03/2023
NexPoint Climate Tech Fund 0 64770 0 64770 64770 0.11 % 30/03/2023
NexPoint Event Driven Fund 0 225000 0 225000 225000 0.39 % 30/03/2023
Drugcrafters, LP 0 1307617 0 1307617 1307617 2.28 % 30/03/2023
NexPoint Real Estate Opportunities, LLC Delaware 0 50000 0 50000 50000 0.09 % 30/03/2023
Highland Global Allocation Fund 0 2156000 0 2156000 2156000 3.76 % 30/03/2023
Drugcrafters, LP Delaware 0 1307617 0 1307617 1307617 2.28 % 30/03/2023
James D. Dondero United States 0 6692447 0 6692447 6692447 11.69 % 30/03/2023
NexPoint Event Driven Fund Delaware 0 225000 0 225000 225000 0.39 % 30/03/2023
Highland Global Allocation Fund Massachusetts 0 2156000 0 2156000 2156000 3.76 % 30/03/2023
(1) BlackRock, Inc. Delaware 868262 0 869224 0 869224 1.6 % 08/07/2022
Identification Nos. of above persons (. Maryland 3887172 0 3887172 0 3887172 7.7 % 07/07/2022
27-4413262 Maryland 3887172 0 3887172 0 3887172 7.7 % 07/07/2022
27-4413262 Maryland 3887172 0 3887172 0 3887172 7.7 % 07/07/2022
Identification Nos. of above persons (. States 3887172 0 3887172 0 3887172 7.7 % 07/07/2022
Laurence W. Lytton USA 3209552 1000 3209552 1000 9 5.9 % 18/05/2022
Laurence W. Lytton USA 3209552 1000 3209552 1000 3210552 11 % 18/05/2022
Drugcrafters, LP Delaware 0 303367 0 303367 303367 0.6 % 11/03/2022
Highland Small-Cap Equity Fund Delaware 0 64770 0 64770 64770 0.13 % 11/03/2022
Drugcrafters, LP Delaware 0 303367 0 303367 303367 0.6 % 11/03/2022
The Dugaboy Investment Trust Delaware 0 2474060 0 2474060 2474060 4.93 % 11/03/2022
NexPoint Real Estate Opportunities, LLC Delaware 0 50000 0 50000 50000 0.01 % 11/03/2022
James D. Dondero Delaware 0 2892197 0 2892197 2892197 5.7 % 11/03/2022
Highland Small-Cap Equity Fund Delaware 0 64770 0 64770 64770 0.13 % 11/03/2022
The Dugaboy Investment Trust Delaware 0 2474060 0 2474060 2474060 4.93 % 11/03/2022
James D. Dondero Delaware 0 2892197 0 2892197 2892197 5.7 % 11/03/2022
NexPoint Real Estate Opportunities, LLC Delaware 0 50000 0 50000 50000 0.01 % 11/03/2022
Identification Nos. of above persons (. States 2820067 0 2820067 0 2820067 5.6 % 09/03/2022
Identification Nos. of above persons (. Maryland 2820067 0 2820067 0 2820067 5.6 % 09/03/2022
27-4413262 Maryland 2820067 0 2820067 0 2820067 5.6 % 09/03/2022
27-4413262 Maryland 2820067 0 2820067 0 2820067 5.6 % 09/03/2022
Highbridge Capital Management, LLC 0 2239937 0 0 2239937 4.27 % 11/02/2022
Highbridge Capital Management, LLC 0 2239937 0 0 2239937 4.27 % 11/02/2022
(1) BlackRock, Inc. Delaware 2953205 0 2977680 0 2977680 5.9 % 02/02/2022
James D. Dondero Delaware 0 2301555 0 0 2301555 5 % 12/02/2021
The Dugaboy Investment Trust Delaware 2161535 0 2161535 0 2161535 4.74 % 12/02/2021
Highland Capital Management Fund Advisors, L.P. 0 90020 0 0 90020 0.2 % 12/02/2021
NexPoint Advisors, L.P. 0 50000 0 0 50000 0.1 % 12/02/2021
Highland Capital Management Fund Advisors, L.P. Delaware 0 90020 0 0 90020 0.2 % 12/02/2021
James D. Dondero 0 2301555 0 0 2301555 5 % 12/02/2021
NexPoint Advisors, L.P. Delaware 0 50000 0 0 50000 0.1 % 12/02/2021
The Dugaboy Investment Trust 2161535 0 2161535 0 2161535 4.74 % 12/02/2021
Highland Capital Management, L.P. Delaware 0 779365 0 779365 779365 2.3 % 14/02/2020
The Dugaboy Investment Trust Delaware 2221535 0 2211535 0 2221535 6.6 % 14/02/2020
James D. Dondero Delaware 0 3178028 0 3178028 3178028 9.6 % 14/02/2020
Strand Advisors, Inc. Delaware 0 779365 0 779365 779365 2.3 % 14/02/2020
Strand Advisors, Inc. Delaware 0 779365 0 779365 779365 2.3 % 14/02/2020
The Dugaboy Investment Trust Delaware 2221535 0 2211535 0 2221535 6.6 % 14/02/2020
James D. Dondero Delaware 0 3178028 0 3178028 3178028 9.6 % 14/02/2020
Highland Capital Management, L.P. Delaware 0 779365 0 779365 779365 2.3 % 14/02/2020
Armistice Capital Master Fund Ltd. Delaware 0 1258000 0 1258000 1258000 3.8 % 14/02/2020
Armistice Capital, LLC Delaware 0 1258000 0 1258000 1258000 3.8 % 14/02/2020
Steven Boyd Delaware 0 1258000 0 1258000 1258000 3.8 % 14/02/2020
Highbridge Capital Management, LLC Delaware 0 2378931 0 0 2378931 6.67 % 13/02/2020
as 1992 Tactical Credit Master Fund, L.P.) Delaware 0 2378931 0 0 2378931 6.67 % 13/02/2020
Highbridge Capital Management, LLC Delaware 0 2378931 0 0 2378931 6.67 % 13/02/2020
as 1992 Tactical Credit Master Fund, L.P.) Delaware 0 2378931 0 0 2378931 6.67 % 13/02/2020
(1) BlackRock, Inc. Delaware 2284660 0 2323912 0 2323912 7 % 05/02/2020
Baupost Group GP, L.L.C.82-3254604 Delaware 0 1552286 0 1552286 1552286 4.66 % 09/12/2019
Baupost Group GP, L.L.C.82-3254604 Delaware 0 1552286 0 1552286 1552286 4.66 % 09/12/2019
The Baupost Group, L.L.C.04-3402144 Delaware 0 1552286 0 1552286 1552286 4.66 % 09/12/2019
Seth A. Klarman Delaware 0 1552286 0 1552286 1552286 4.66 % 09/12/2019
Seth A. Klarman Delaware 0 1552286 0 1552286 1552286 4.66 % 09/12/2019
The Baupost Group, L.L.C.04-3402144 Delaware 0 1552286 0 1552286 1552286 4.66 % 09/12/2019
UBS Group AG directly and on behalf of certain subsidiaries Switzerland 0 2119933 0 2119933 2119933 6.6 % 15/02/2019
Strand Advisors, Inc. Delaware 0 2204865 0 2204865 2204865 6.9 % 14/02/2019
Strand Advisors, Inc. Delaware 0 2204865 0 2204865 2204865 6.9 % 14/02/2019
Highland Capital Management, L.P. Delaware 0 2204865 0 2204865 2204865 6.9 % 14/02/2019
James D. Dondero Delaware 0 3153028 0 3153028 3153028 9.8 % 14/02/2019
James D. Dondero Delaware 0 3153028 0 3153028 3153028 9.8 % 14/02/2019
Highland Capital Management, L.P. Delaware 0 2204865 0 2204865 2204865 6.9 % 14/02/2019
Highbridge Capital Management, LLC Delaware 0 2799479 0 0 2799479 8.04 % 14/02/2019
Steven Boyd Delaware 0 1672000 0 1672000 1672000 5.2 % 13/11/2018
Armistice Capital, LLC Delaware 0 1672000 0 1672000 1672000 5.2 % 13/11/2018
Armistice Capital, LLC Cayman Islands 0 1672000 0 1672000 1672000 5.2 % 13/11/2018
Armistice Capital Master Fund Ltd. Delaware 0 1672000 0 1672000 1672000 5.2 % 13/11/2018
Steven Boyd Cayman Islands 0 1672000 0 1672000 1672000 5.2 % 13/11/2018
Armistice Capital Master Fund Ltd. Cayman Islands 0 1672000 0 1672000 1672000 5.2 % 13/11/2018
Highbridge Capital Management, LLC State of Delaware 0 2201258 0 0 2201258 6.54 % 30/04/2018
Highbridge Capital Management, LLC State of Delaware 0 2201258 0 0 2201258 6.54 % 30/04/2018
VI, LP England 0 1041131 0 0 1041131 3.7 % 14/02/2018
98-051-8585 England 0 1041131 0 0 1041131 3.7 % 14/02/2018
Seth A. Klarman Delaware 0 2394498 0 2394498 2394498 8.57 % 13/02/2018
Seth A. Klarman Delaware 0 2394498 0 2394498 2394498 8.57 % 13/02/2018
The Baupost Group, L.L.C.04-3402144 Delaware 0 2394498 0 2394498 2394498 8.57 % 13/02/2018
Baupost Group GP, L.L.C.82-3254604 Delaware 0 2394498 0 2394498 2394498 8.57 % 13/02/2018
The Baupost Group, L.L.C.04-3402144 Delaware 0 2394498 0 2394498 2394498 8.57 % 13/02/2018
Baupost Group GP, L.L.C.82-3254604 Delaware 0 2394498 0 2394498 2394498 8.57 % 13/02/2018
HBM Healthcare Investments (Cayman) Ltd. Cayman Islands British West Indies 1353202 0 1353202 0 1353202 5.97 % 14/02/2017
Seth A. Klarman Commonwealth Massachusetts 0 2044498 0 2044498 2044498 9.04 % 14/02/2017
The Baupost Group, L.L.C.04-3402144 Commonwealth Massachusetts 0 2044498 0 2044498 2044498 9.04 % 14/02/2017
The Baupost Group, L.L.C.04-3402144 Commonwealth Massachusetts 0 2044498 0 2044498 2044498 9.04 % 14/02/2017
SAK Corporation04-3334541 Commonwealth Massachusetts 0 2044498 0 2044498 2044498 9.04 % 14/02/2017
(1) BlackRock, Inc. Delaware 1280676 0 1300022 0 1300022 5.7 % 30/01/2017
VI, LP England 0 1301413 0 0 1301413 7.4 % 16/02/2016
98-051-8585 England 0 1301413 0 0 1301413 7.4 % 16/02/2016
Seth A. Klarman Commonwealth Massachusetts 0 1544498 0 1544498 1544498 8.77 % 12/02/2016
SAK Corporation04-3334541 Commonwealth Massachusetts 0 1544498 0 1544498 1544498 8.77 % 12/02/2016
The Baupost Group, L.L.C.04-3402144 Commonwealth Massachusetts 0 1544498 0 1544498 1544498 8.77 % 12/02/2016
98-051-8585 England 0 1310482 0 0 1310482 9.1 % 06/02/2015
98-051-8585 England 0 1310482 0 0 1310482 9.1 % 06/02/2015
VI, LP England 0 1301413 0 0 1301413 9 % 06/02/2015
VI, LP England 0 1301413 0 0 1301413 9 % 06/02/2015
Seth A. Klarman Commonwealth Massachusetts 0 1735218 0 1735218 1735218 12.04 % 11/12/2014
SAK Corporation04-3334541 Commonwealth Massachusetts 0 1735218 0 1735218 1735218 12.04 % 11/12/2014
The Baupost Group, L.L.C.04-3402144 Commonwealth Massachusetts 0 1735218 0 1735218 1735218 12.04 % 11/12/2014
SAK Corporation04-3334541 Commonwealth Massachusetts 0 1735218 0 1735218 1735218 12.04 % 11/12/2014
Seth A. Klarman Commonwealth Massachusetts 0 1735218 0 1735218 1735218 12.04 % 11/12/2014
The Baupost Group, L.L.C.04-3402144 Commonwealth Massachusetts 0 1735218 0 1735218 1735218 12.04 % 11/12/2014
Edward C. Johnson 3d Delaware 0 0 1735218 0 1735218 12.035 % 10/12/2014
Edward C. Johnson 3d Delaware 0 0 1735218 0 1735218 12.035 % 10/12/2014
FMR LLC Delaware 0 0 1735218 0 1735218 12.035 % 10/12/2014
Abigail P. Johnson Delaware 0 0 1735218 0 1735218 12.035 % 10/12/2014
Select Biotechnology Portfolio Delaware 1336118 0 0 0 1336118 9.267 % 10/12/2014
Select Biotechnology Portfolio Delaware 1336118 0 0 0 1336118 9.267 % 10/12/2014
Abigail P. Johnson Delaware 0 0 1735218 0 1735218 12.035 % 10/12/2014
FMR LLC Delaware 0 0 1735218 0 1735218 12.035 % 10/12/2014
HBM Healthcare Investments (Cayman) Ltd. Cayman Islands, British West Indies 1771462 0 1771462 10 1771462 12.28 % 12/11/2014
James C. Roumell (“Roumell”) U.S.A. 130345 134989 130345 0 265334 8 % 10/11/2014
52-2145132 Maryland 128305 134989 128305 0 263294 8 % 10/11/2014
52-2145132 Maryland 128305 134989 128305 0 263294 8 % 10/11/2014
James C. Roumell (“Roumell”) Maryland 130345 134989 130345 0 265334 8 % 10/11/2014
EcoR1 Capital Fund, L.P. Delaware 0 478514 0 0 478514 2.5 % 29/08/2014
EcoR1 Capital Fund Qualified, L.P. Delaware 0 579686 0 0 579686 3 % 29/08/2014
Oleg Nodelman United States 0 1058200 0 0 1058200 5.5 % 29/08/2014
EcoR1 Capital Fund, L.P. Delaware 0 478514 0 0 478514 2.5 % 29/08/2014
Oleg Nodelman Delaware 0 1058200 0 0 1058200 5.5 % 29/08/2014
EcoR1 Capital, LLC Delaware 0 1058200 0 0 1058200 5.5 % 29/08/2014
EcoR1 Capital, LLC Delaware 0 1058200 0 0 1058200 5.5 % 29/08/2014
EcoR1 Capital Fund Qualified, L.P. Delaware 0 579686 0 0 579686 3 % 29/08/2014
Franklin Advisers, Inc. Maryland 300000 1882991 300000 1882991 12840000 10.5 % 18/12/2013
John T. Bird UNITED STATES OF AMERICA 0 1123381 0 0 1123381 6 % 14/08/2013
Peter M. Collery UNITED STATES OF AMERICA 0 1265365 0 0 1265365 6.7 % 14/08/2013
David A. Hurwitz UNITED STATES OF AMERICA 1750 1123381 1750 0 1125131 6 % 14/08/2013
SC Fundamental LLC NEW YORK 0 1123381 0 0 1123381 6 % 14/08/2013
Fundamental Value Fund, L.P. DELAWARE 0 1123381 0 0 1123381 6 % 14/08/2013
SC Fundamental LLC Employee Savings and Profit Sharing Plan UNITED STATES OF AMERICA 0 141984 0 0 141984 0.8 % 14/08/2013
Neil H. Koffler UNITED STATES OF AMERICA 0 1123381 0 0 1123381 6 % 14/08/2013
David A. Hurwitz Delaware 0 1123381 0 0 1123381 6 % 02/08/2013
SC Fundamental LLC Delaware 0 1123381 0 0 1123381 6 % 02/08/2013
Peter M. Collery Delaware 0 1265365 0 0 1265365 6.7 % 02/08/2013
Savings and Profit Sharing Plan Delaware 0 141984 0 0 141984 0.8 % 02/08/2013
SC Fundamental Value Fund, L.P. Delaware 0 1123381 0 0 1123381 6 % 02/08/2013
John T. Bird Delaware 0 1123381 0 0 1123381 6 % 02/08/2013
Neil H. Koffler Delaware 0 1123381 0 0 1123381 6 % 02/08/2013
Sabby Healthcare Volatility Master Fund, Ltd. Cayman Islands 0 1434976 0 1434976 1434976 7.74 % 08/06/2012
KEVIN C. TANG DELAWARE 0 1750000 0 1750000 1750000 9.5 % 04/05/2012
KEVIN C. TANG DELAWARE 0 1750000 0 1750000 1750000 9.5 % 04/05/2012
TANG CAPITAL MANAGEMENT, LLC DELAWARE 0 1750000 0 1750000 1750000 9.5 % 04/05/2012
TANG CAPITAL PARTNERS, LP DELAWARE 0 1750000 0 1750000 1750000 9.5 % 04/05/2012
TANG CAPITAL MANAGEMENT, LLC DELAWARE 0 1750000 0 1750000 1750000 9.5 % 04/05/2012
TANG CAPITAL PARTNERS, LP DELAWARE 0 1750000 0 1750000 1750000 9.5 % 04/05/2012
HealthCor Offshore GP, LLC Delaware 0 412993 0 412993 412993 2.97 % 30/03/2012
Arthur Cohen Delaware 0 700000 0 700000 700000 5.03 % 30/03/2012
HealthCor Hybrid Offshore GP, LLC Delaware 0 24867 0 24867 24867 0.18 % 30/03/2012
HealthCor Group, LLC Delaware 0 700000 0 700000 700000 5.03 % 30/03/2012
HealthCor Hybrid Offshore Master Fund, L.P. Delaware 0 24867 0 24867 24867 0.18 % 30/03/2012
HealthCor Associates, LLC Delaware 0 13 0 700000 700000 5.03 % 30/03/2012
HealthCor Offshore Master Fund, L.P. Delaware 0 412993 0 412993 412993 2.97 % 30/03/2012
HealthCor Management, L.P. Delaware 0 13 0 700000 700000 5.03 % 30/03/2012
HealthCor Long Master GP, LLC Delaware 0 13 0 100000 100000 0.72 % 30/03/2012
HealthCor Long Offshore Master Fund, L.P. Delaware 0 13 0 100000 100000 0.72 % 30/03/2012
Joseph Healey Delaware 0 13 0 700000 700000 5.03 % 30/03/2012
Arthur Cohen Delaware 0 13 0 700000 700000 5.03 % 30/03/2012
HealthCor, L.P. Delaware 0 13 0 162140 162140 1.17 % 30/03/2012
HealthCor Capital, L.P. Delaware 0 13 0 162140 162140 1.17 % 30/03/2012
HealthCor Group, LLC Delaware 0 13 0 13 700000 5.03 % 30/03/2012
HealthCor Hybrid Offshore GP, LLC Delaware 0 0 13 24867 24867 0.18 % 30/03/2012
HealthCor Hybrid Offshore Master Fund, L.P. Delaware 0 13 24867 24867 24867 0.18 % 30/03/2012
HealthCor Offshore GP, LLC Delaware 0 13 0 412993 412993 2.97 % 30/03/2012
HealthCor Offshore Master Fund, L.P. Delaware 0 13 0 412993 412993 2.97 % 30/03/2012
HealthCor Management, L.P. Delaware 0 700000 0 700000 700000 5.03 % 30/03/2012
HealthCor Associates, LLC Delaware 0 700000 0 700000 700000 5.03 % 30/03/2012
HealthCor Capital, L.P. Delaware 0 162140 0 162140 162140 1.17 % 30/03/2012
HealthCor, L.P. Delaware 0 162140 0 162140 162140 1.17 % 30/03/2012
HealthCor Long Master GP, LLC Delaware 0 100000 0 100000 100000 0.72 % 30/03/2012
HealthCor Long Offshore Master Fund, L.P. Delaware 0 100000 0 100000 100000 0.72 % 30/03/2012
Joseph Healey Delaware 0 700000 0 700000 700000 5.03 % 30/03/2012
Manish Chapekar United States 0 58178 0 10 58178 0.4 % 05/03/2010
Howard D. Palefsky United States 0 1265202 0 10 1265202 9.5 % 05/03/2010
Daniel K. Turner, III United States 0 1265202 0 10 1265202 9.5 % 05/03/2010
Montreux Equity Partners III SBIC, L.P. California 0 652318 0 10 652318 4.9 % 05/03/2010
Montreux Equity Partners II SBIC, L.P. California 0 554706 0 10 554706 4.2 % 05/03/2010
Montreux Equity Management II SBIC, LLC California 0 554706 0 10 554706 4.2 % 05/03/2010
Montreux IV Associates, L.L.C. California 0 58178 0 10 58178 0.4 % 05/03/2010
Montreux Equity Management III SBIC, LLC California 0 652318 0 10 652318 4.9 % 05/03/2010
Montreux Equity Management IV, LLC California 0 58178 0 10 58178 0.4 % 05/03/2010
John Savarese, M.D. United States 0 58178 0 10 58178 0.4 % 05/03/2010
Gilbert H. Kliman (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Thomas L. Rosch (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Harvey B. Cash (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
W. Stephen Holmes III (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Khaled A. Nasr (a Venture Member of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
InterWest Partners IX, LP United States 0 0 0 0 1251808 9.4 % 16/02/2010
Michael B. Sweeney (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
InterWest Management Partners IX, LLC (the General Partner of InterWest Partners IX, LP) United States 0 0 0 0 1251808 9.4 % 16/02/2010
Christopher B. Ehrlich (a Venture Member of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1255502 9.4 % 16/02/2010
Arnold L. Oronsky (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Philip T. Gianos (a Managing Director of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Linda S. Grais (a Venture Member of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Nina S. Kjellson (a Venture Member of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Bruce A. Cleveland (a Venture Member of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
Douglas A. Pepper (a Venture Member of InterWest Management Partners IX, LLC) United States 0 0 0 1251808 1251808 9.4 % 16/02/2010
DP V Associates, L.P. Delaware 0 0 0 0 0 0 % 19/01/2010
Domain Associates, L.L.C. Delaware 0 0 0 0 0 0 % 19/01/2010
Domain Partners V, L.P. Delaware 0 0 0 0 0 0 % 19/01/2010
Florian Schönharting Denmark 0 757688 0 757688 757688 5.78 % 13/10/2009
Christian Hansen Denmark 0 757688 0 757688 757688 5.78 % 13/10/2009
Cora Madsen United States 0 757688 0 757688 757688 5.78 % 13/10/2009
ApS Denmark 0 757688 0 757688 757688 5.78 % 13/10/2009
NB Public Equity K/S Denmark 0 757688 0 757688 757688 5.78 % 13/10/2009
WILLIAM J. LINK : 0 0 0 2074668 2074668 8.2 % 12/02/2008
SAMUEL D. COLELLA : 0 0 0 2074668 2074668 8.2 % 12/02/2008
CHARLES M. WARDEN : 0 0 0 2074668 2074668 8.2 % 12/02/2008
REBECCA B. ROBERTSON : 0 0 0 2074668 2074668 8.2 % 12/02/2008
VERSANT VENTURES CAPITAL II, L.P :: 0 0 0 0 2044744 8.1 % 12/02/2008
DONALD B. MILDER : 0 0 0 2074668 2074668 8.2 % 12/02/2008
CAMILLE D. SAMUELS : 0 0 0 2074668 2142881 8.5 % 12/02/2008
BARBARA N. LUBASH : 0 0 0 2074668 2074668 8.2 % 12/02/2008
BRADLEY J. BOLZON : 0 0 0 2074668 2074668 8.2 % 12/02/2008
BRIAN G. ATWOOD : 0 0 0 2074668 2074668 8.2 % 12/02/2008
VERSANT VENTURES II, LLC : 0 0 0 0 2074668 8.2 % 12/02/2008
VERSANT SIDE FUND II, L.P. : 0 0 0 0 16211 0.06 % 12/02/2008
VERSANT AFFILIATES FUND II-A, LP : 0 0 0 0 13713 0.05 % 12/02/2008
ROSS A. JAFFE : 0 0 0 2074668 2074668 8.2 % 12/02/2008
Sofinnova Venture Affiliates V, L.P. (“SVA V”) Delaware 50861 50861 50861 0 50861 0.2 % 11/02/2008
Sofinnova Venture Principals V, LP (“SVPr V”) Delaware 32451 32451 32451 0 32451 0.1 % 11/02/2008
Sofinnova Management V, L.L.C. (“SM V”) Delaware 83312 2135224 83312 0 2218536 8.9 % 11/02/2008
Sofinnova Management V 2005 L.L.C. (“SMV 2005”) Delaware 0 2135224 0 0 2135224 8.5 % 11/02/2008
Sofinnova Venture Partners V, L.P. (“SVP V”) Delaware 2135224 0 2135224 0 2135224 8.5 % 11/02/2008
ACCIPITER LIFE SCIENCES FUND II, LP DELAWARE 5012 0 5012 0 5012 0.02 % 21/12/2007
FUND II (QP), LP DELAWARE 5767 0 5767 0 5767 0.02 % 21/12/2007
LP DELAWARE 717877 0 717877 0 717877 2.9 % 21/12/2007
CAPITAL, LLC DELAWARE 0 728656 0 0 728656 2.9 % 21/12/2007
ACCIPITER LIFE SCIENCES FUND (OFFSHORE), LTD. CAYMAN ISLANDS 716132 0 716132 0 716132 2.8 % 21/12/2007
HOFFMAN USA 0 1454689 0 0 1454689 5.8 % 21/12/2007
CAPITAL MANAGEMENT, LLC DELAWARE 0 726033 0 0 726033 2.9 % 21/12/2007
ACCIPITER LIFE SCIENCES FUND II (OFFSHORE), LTD. CAYMAN ISLANDS 9901 0 9901 0 9901 0.04 % 21/12/2007
(ii) Bermuda 0 800000 0 800000 800000 3.4 % 11/06/2007
(ii) Bermuda 0 1168159 0 1168159 1168159 5.1 % 20/04/2007
Edward C. Johnson 3d United States of America 0 0 1678163 0 1678163 7.241 % 14/02/2007
FMR Corp. Delaware 0 0 1678163 0 1678163 7.241 % 14/02/2007
EIN No.: : 0 0 0 0 1662864 7.18 % 14/02/2007
EIN No.: : 0 0 0 0 1662864 7.18 % 14/02/2007
VERSANT VENTURE CAPITAL II, L.P : 0 0 0 0 2044744 8.9 % 09/02/2007
BRADLEY J. BOLZON : 0 0 0 2074668 2074668 9.1 % 09/02/2007
BRIAN G. ATWOOD : 0 0 0 2074668 2074668 9.1 % 09/02/2007
CHARLES M. WARDEN : 0 0 0 2074668 2074668 9.1 % 09/02/2007
BARBARA N. LUBASH : 0 0 0 2074668 2074668 9.1 % 09/02/2007
WILLIAM J. LINK : 0 0 0 2074668 2074668 9.1 % 09/02/2007
ROSS A. JAFFE : 0 0 0 2074668 2074668 9.1 % 09/02/2007
SAMUEL D. COLELLA : 0 0 0 2074668 2074668 9.1 % 09/02/2007
REBECCA B. ROBERTSON : 0 0 0 2074668 2074668 9.1 % 09/02/2007
VERSANT VENTURES II, LLC : 0 0 0 0 2074668 9.1 % 09/02/2007
DONALD B. MILDER : 0 0 0 2074668 2074668 9.1 % 09/02/2007
VERSANT SIDE FUND II, L.P. : 0 0 0 0 16211 0.07 % 09/02/2007
VERSANT AFFILIATES FUND II-A, LP : 0 0 0 0 13713 0.06 % 09/02/2007
CAMILLE D. SAMUELS : 0 0 0 2074668 2130381 9.3 % 09/02/2007

Senat trading

Bureau Date de la transaction Date de réception Type Amount Commentaire

Senat Divulgation

Représentant Date de la transaction Date de divulgation Type Amount District