| Finny Kuruvilla, M.D. Ph. D. |
United States |
0 |
7090108 |
0 |
0 |
7090108 |
9.97 % |
06/11/2024 |
| Eventide Asset Management, LLC |
Delaware |
7090108 |
0 |
7090108 |
0 |
7090108 |
9.97 % |
06/11/2024 |
| Robin C. John |
United States |
0 |
7090108 |
0 |
0 |
7090108 |
9.97 % |
06/11/2024 |
| Abigail P. Johnson |
United States of America |
0 |
0 |
5075837 |
0 |
5075837 |
7.138 % |
07/10/2024 |
| FMR LLC |
Delaware |
5071674 |
0 |
5075837 |
0 |
5075837 |
7.138 % |
07/10/2024 |
| FMR LLC |
Delaware |
5071674 |
0 |
5075837 |
0 |
5075837 |
7.138 % |
07/10/2024 |
| Abigail P. Johnson |
Delaware |
0 |
0 |
5075837 |
0 |
5075837 |
7.138 % |
07/10/2024 |
| 2. |
Delaware |
0 |
3613178 |
0 |
0 |
10 |
5.1 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3613178 |
0 |
0 |
10 |
5.1 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3613178 |
0 |
0 |
10 |
5.1 % |
17/11/2023 |
| 2. |
Delaware |
0 |
143312 |
0 |
0 |
10 |
0.2 % |
17/11/2023 |
| 2. |
Delaware |
0 |
226651 |
0 |
0 |
10 |
0.3 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3839829 |
0 |
0 |
10 |
5.4 % |
17/11/2023 |
| 2. |
Delaware |
0 |
226651 |
0 |
0 |
10 |
0.3 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3839829 |
0 |
0 |
10 |
5.4 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3613178 |
0 |
0 |
10 |
5.1 % |
17/11/2023 |
| 2. |
Delaware |
0 |
226651 |
0 |
0 |
10 |
0.3 % |
17/11/2023 |
| 2. |
Delaware |
0 |
143312 |
0 |
0 |
10 |
0.2 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3613178 |
0 |
0 |
10 |
5.1 % |
17/11/2023 |
| 2. |
Delaware |
0 |
3613178 |
0 |
0 |
10 |
5.1 % |
17/11/2023 |
| 2. |
Delaware |
0 |
226651 |
0 |
0 |
10 |
0.3 % |
17/11/2023 |
| Finny Kuruvilla, M.D. Ph. D. |
Delaware |
0 |
7814039 |
0 |
0 |
7814039 |
11.07 % |
10/10/2023 |
| Robin C. John |
Delaware |
0 |
7814039 |
0 |
0 |
7814039 |
11.07 % |
10/10/2023 |
| Robin C. John |
Delaware |
0 |
7814039 |
0 |
0 |
7814039 |
11.07 % |
10/10/2023 |
| Finny Kuruvilla, M.D. Ph. D. |
Delaware |
0 |
7814039 |
0 |
0 |
7814039 |
11.07 % |
10/10/2023 |
| Eventide Asset Management, LLC |
Delaware |
7814039 |
0 |
7814039 |
0 |
7814039 |
11.07 % |
10/10/2023 |
| Eventide Asset Management, LLC |
Delaware |
7814039 |
0 |
7814039 |
0 |
7814039 |
11.07 % |
10/10/2023 |
| VISWANATHAN KRISHNAN |
United Kingdom |
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| TYBOURNE CAPITAL MANAGEMENT (HK) LIMITED |
|
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| TYBOURNE KESARI LIMITED |
|
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| TYBOURNE KESARI LIMITED |
Cayman Islands |
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| TYBOURNE CAPITAL MANAGEMENT (HK) LIMITED |
Hong Kong |
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| TYBOURNE CAPITAL MANAGEMENT LIMITED |
|
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| VISWANATHAN KRISHNAN |
|
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| TYBOURNE CAPITAL MANAGEMENT LIMITED |
Cayman Islands |
0 |
2231427 |
0 |
2231427 |
2231427 |
3.9 % |
14/02/2023 |
| 95-1411037 |
Delaware |
3048182 |
0 |
3048182 |
0 |
13 |
5.3 % |
13/02/2023 |
| 95-1411037 |
Delaware |
3048182 |
0 |
3048182 |
0 |
13 |
5.3 % |
13/02/2023 |
| STATE STREET CORPORATION |
|
0 |
3004971 |
0 |
3084137 |
3084137 |
5.4 % |
07/02/2023 |
| Wellington Management Company LLP |
Massachusetts |
0 |
3160910 |
0 |
0 |
3492649 |
6.12 % |
06/02/2023 |
| Wellington Investment Advisors Holdings LLP |
Massachusetts |
0 |
3179876 |
0 |
0 |
3618493 |
6.34 % |
06/02/2023 |
| Wellington Management Group LLP |
Massachusetts |
0 |
3179876 |
0 |
0 |
3618493 |
6.34 % |
06/02/2023 |
| Wellington Group Holdings LLP |
Massachusetts |
0 |
3179876 |
0 |
0 |
3618493 |
6.34 % |
06/02/2023 |
| Wellington Group Holdings LLP |
Massachusetts |
0 |
3179876 |
0 |
0 |
3618493 |
6.34 % |
06/02/2023 |
| Wellington Management Group LLP |
Massachusetts |
0 |
3179876 |
0 |
0 |
3618493 |
6.34 % |
06/02/2023 |
| Wellington Investment Advisors Holdings LLP |
Massachusetts |
0 |
3179876 |
0 |
0 |
3618493 |
6.34 % |
06/02/2023 |
| Wellington Management Company LLP |
Massachusetts |
0 |
3160910 |
0 |
0 |
3492649 |
6.12 % |
06/02/2023 |
| David E. Goel |
United States of America |
0 |
9199973 |
0 |
10 |
9199973 |
16.45 % |
03/06/2022 |
| Matrix Capital Management Company LP |
State of Delaware |
0 |
9199973 |
0 |
10 |
9199973 |
16.45 % |
03/06/2022 |
| David E. Goel |
|
0 |
9199973 |
0 |
11 |
9199973 |
16.45 % |
03/06/2022 |
| Matrix Capital Management Company LP |
|
0 |
9199973 |
0 |
11 |
9199973 |
16.45 % |
03/06/2022 |
| Redmile Group, LLC |
|
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2022 |
| Jeremy C. Green |
|
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2022 |
| Jeremy C. Green |
United Kingdom |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2022 |
| Redmile Group, LLC |
Delaware |
0 |
0 |
0 |
0 |
0 |
0 % |
14/02/2022 |
| 52-0556948 |
Maryland |
865677 |
0 |
4382881 |
0 |
4382881 |
9.6 % |
14/02/2022 |
| 52-0556948 |
Maryland |
865677 |
0 |
4382881 |
0 |
4382881 |
9.6 % |
14/02/2022 |
| TYBOURNE CAPITAL MANAGEMENT (HK) LIMITED |
|
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| TYBOURNE CAPITAL MANAGEMENT (HK) LIMITED |
Hong Kong |
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| TYBOURNE CAPITAL MANAGEMENT LIMITED |
Cayman Islands |
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| TYBOURNE KESARI LIMITED |
Cayman Islands |
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| TYBOURNE CAPITAL MANAGEMENT LIMITED |
|
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| VISWANATHAN KRISHNAN |
United Kingdom |
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| TYBOURNE KESARI LIMITED |
|
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| VISWANATHAN KRISHNAN |
|
0 |
2628409 |
0 |
2628409 |
2628409 |
5.8 % |
14/02/2022 |
| Matrix Capital Management Company LP |
|
4349279 |
0 |
4349279 |
0 |
4349279 |
9.6 % |
14/02/2022 |
| David E. Goel |
|
4349279 |
0 |
4349279 |
0 |
4349279 |
9.6 % |
14/02/2022 |
| David E. Goel |
United States |
4349279 |
0 |
4349279 |
0 |
4349279 |
9.6 % |
14/02/2022 |
| Matrix Capital Management Company LP |
State of Delaware |
4349279 |
0 |
4349279 |
0 |
4349279 |
9.6 % |
14/02/2022 |
| Anthony Y. Sun |
United States |
1442825 |
1416552 |
1442825 |
0 |
2859377 |
6.2 % |
10/02/2022 |
| (1) BlackRock, Inc. |
Delaware |
2818370 |
0 |
2842945 |
0 |
2842945 |
6.3 % |
03/02/2022 |
| Avidity Master Fund LP |
Delaware |
0 |
2445405 |
0 |
2445405 |
2445405 |
5.4 % |
01/02/2022 |
| David Witzke |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Michael Gregory |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Partners Management LP |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Capital Partners (GP) LLC |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Capital Partners Fund (GP) LP |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Capital Partners (GP) LLC |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Partners Management (GP) LLC |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Michael Gregory |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Capital Partners Fund (GP) LP |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Master Fund LP |
Delaware |
0 |
2445405 |
0 |
2445405 |
2445405 |
5.4 % |
01/02/2022 |
| Avidity Partners Management (GP) LLC |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Avidity Partners Management LP |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| David Witzke |
Delaware |
0 |
3022790 |
0 |
3022790 |
3022790 |
6.7 % |
01/02/2022 |
| Redmile Group, LLC |
Delaware |
0 |
2416406 |
0 |
0 |
2416406 |
6 % |
16/02/2021 |
| Jeremy C. Green |
Delaware |
0 |
2416406 |
0 |
0 |
2416406 |
6 % |
16/02/2021 |
| Jeremy C. Green |
Delaware |
0 |
2416406 |
0 |
0 |
2416406 |
6 % |
16/02/2021 |
| Redmile Group, LLC |
Delaware |
0 |
2416406 |
0 |
0 |
2416406 |
6 % |
16/02/2021 |
| Matrix Capital Management Company LP |
State of Delaware |
3821739 |
0 |
3821739 |
0 |
3821739 |
9.41 % |
16/02/2021 |
| David E. Goel |
Delaware |
3821739 |
0 |
3821739 |
0 |
3821739 |
9.41 % |
16/02/2021 |
| Matrix Capital Management Company LP |
Delaware |
3821739 |
0 |
3821739 |
0 |
3821739 |
9.41 % |
16/02/2021 |
| David E. Goel |
United States |
3821739 |
0 |
3821739 |
0 |
3821739 |
9.41 % |
16/02/2021 |
| Viking Global Investors LP |
Delaware |
0 |
3011284 |
0 |
3011284 |
3011284 |
7.4 % |
12/02/2021 |
| The Vanguard Group - 23-1945930 |
Pennsylvania For |
0 |
0 |
0 |
68767 |
2346137 |
5.78 % |
10/02/2021 |
| The Vanguard Group - 23-1945930 |
Pennsylvania For |
0 |
0 |
0 |
68767 |
2346137 |
5.78 % |
10/02/2021 |
| Anthony Y. Sun |
United States |
1804005 |
1187902 |
1804005 |
0 |
2991907 |
7.3 % |
03/02/2021 |
| (1) BlackRock, Inc. |
Delaware |
2252561 |
0 |
2275149 |
0 |
2275149 |
5.6 % |
02/02/2021 |
| FMR LLC |
Delaware |
700889 |
0 |
5006172 |
0 |
5006172 |
12.323 % |
10/11/2020 |
| FMR LLC |
Delaware |
700889 |
0 |
5006172 |
0 |
5006172 |
12.323 % |
10/11/2020 |
| TYBOURNE CAPITAL MANAGEMENT (HK) LIMITED |
Hong Kong |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| VISWANATHAN KRISHNAN |
Hong Kong |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| TYBOURNE KESARI LIMITED |
Cayman Islands |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| VISWANATHAN KRISHNAN |
United Kingdom |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| TYBOURNE KESARI LIMITED |
Hong Kong |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| TYBOURNE CAPITAL MANAGEMENT LIMITED |
Cayman Islands |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| TYBOURNE CAPITAL MANAGEMENT (HK) LIMITED |
Hong Kong |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| TYBOURNE CAPITAL MANAGEMENT LIMITED |
Hong Kong |
0 |
2664409 |
0 |
2664409 |
2664409 |
7.4 % |
29/05/2020 |
| Viking Global Investors LP |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Andreas Halvorsen |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities Illiquid Investments Sub-Master LP |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities GP LLC |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities Portfolio GP LLC |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| C. Ott |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Investors LP |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities GP LLC |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities Portfolio GP LLC |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities Illiquid Investments Sub-Master LP |
Cayman Islands |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Andreas Halvorsen |
Norway |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| C. Ott |
United States |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| S. Shabet |
United States |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities Liquid Portfolio Sub-Master LP |
Cayman Islands |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Viking Global Opportunities Liquid Portfolio Sub-Master LP |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| S. Shabet |
Delaware |
0 |
4443284 |
0 |
0 |
4443284 |
13 % |
14/04/2020 |
| Citadel Advisors Holdings LP |
Delaware |
0 |
2129766 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Citadel GP LLC |
Delaware |
0 |
2129766 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| CALC IV LP |
Delaware |
0 |
198 |
0 |
0 |
10 |
12 % |
09/04/2020 |
| Citadel Securities GP LLC |
Delaware |
0 |
198 |
0 |
0 |
10 |
12 % |
09/04/2020 |
| CALC IV LP |
Delaware |
0 |
198 |
0 |
0 |
10 |
12 % |
09/04/2020 |
| Citadel Advisors Holdings LP |
Delaware |
0 |
2129766 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Citadel Advisors LLC |
Delaware |
0 |
2129766 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Kenneth Griffin |
Delaware |
0 |
2129964 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Citadel Securities GP LLC |
Delaware |
0 |
198 |
0 |
0 |
10 |
12 % |
09/04/2020 |
| Kenneth Griffin |
Delaware |
0 |
2129964 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Citadel Securities LLC |
Delaware |
0 |
198 |
0 |
0 |
10 |
12 % |
09/04/2020 |
| Citadel GP LLC |
Delaware |
0 |
2129766 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Citadel Advisors LLC |
Delaware |
0 |
2129766 |
0 |
0 |
10 |
5.9 % |
09/04/2020 |
| Citadel Securities LLC |
Delaware |
0 |
198 |
0 |
0 |
10 |
12 % |
09/04/2020 |